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anti-AHCYL1 antibody :: Rabbit S-adenosylhomocysteine hydrolase-like 1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS710923 anti-AHCYL1 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

S-adenosylhomocysteine hydrolase-like 1 (AHCYL1), Polyclonal Antibody

 Also Known As   

Rabbit anti-human S-adenosylhomocysteine hydrolase-like 1 polyclonal Antibody

 Product Synonym Names    S-adenosylhomocysteine hydrolase-like 1; AHCYL1; DCAL; IRBIT; PRO0233; XPVKONA
 Product Gene Name   

anti-AHCYL1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    607826
 3D Structure    ModBase 3D Structure for O43865
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human AHCYL1
 Storage Buffer    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-162507
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-AHCYL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-AHCYL1 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for AHCYL1. It may not necessarily be applicable to this product.
 NCBI GI #    55665978
 NCBI GeneID    10768
 NCBI Accession #    CAH70966.1 [Other Products]
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 UniProt Primary Accession #    O43865 [Other Products]
 UniProt Secondary Accession #    Q2TAJ6; Q502W8; Q5VSM0; Q6P171; Q96PK4; Q9UG84; B4E168 [Other Products]
 UniProt Related Accession #    O43865 [Other Products]
 Molecular Weight    53,753 Da [Similar Products]
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 NCBI Official Full Name    S-adenosylhomocysteine hydrolase-like 1
 NCBI Official Synonym Full Names    adenosylhomocysteinase-like 1
 NCBI Official Symbol    AHCYL1 [Similar Products]
 NCBI Official Synonym Symbols   
DCAL; IRBIT; PPP1R78; PRO0233; XPVKONA
[Similar Products]
 NCBI Protein Information    putative adenosylhomocysteinase 2; adoHcyase 2; DC-expressed AHCY-like molecule; S-adenosyl-L-homocysteine hydrolase 2; S-adenosyl homocysteine hydrolase homolog; dendritic cell expressed AHCY-like protein; protein phosphatase 1, regulatory subunit 78; S-adenosylhomocysteine hydrolase-like protein 1; inositol 1,4,5-trisphosphate receptor-binding protein
 UniProt Protein Name    Putative adenosylhomocysteinase 2
 UniProt Synonym Protein Names   
DC-expressed AHCY-like molecule; S-adenosyl-L-homocysteine hydrolase 2; S-adenosylhomocysteine hydrolase-like protein 1
 Protein Family    Adenosylhomocysteinase
 UniProt Gene Name    AHCYL1 [Similar Products]
 UniProt Synonym Gene Names    DCAL; XPVKONA; AdoHcyase 2 [Similar Products]
 UniProt Entry Name    SAHH2_HUMAN
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 NCBI Summary for AHCYL1    The protein encoded by this gene interacts with inositol 1,4,5-trisphosphate receptor, type 1 and may be involved in the conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
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 UniProt Comments for AHCYL1    AHCYL1: an inositol 1,4,5-trisphosphate receptor 1 (IP3R1)-binding protein that inhibits IP3 binding to IP3R1 and IP3-induced intracellular Ca2 release. Suppresses the activation of IP3R1 via a phosphorylation-dependent mechanism. Also binds the Na/HCO3 cotransporter 1 (SLC4A4) and may play an important role in pH regulation. Contains a domain homologous to S-adenosylhomocysteine hydrolase (SAHH), although it is reported to possess no hydrolase activity. Its expression is induced in cultured monocytes when they are differentiated into dendritic cells (DC) by exposure to GM-CSF and IL-4.

Protein type: Amino Acid Metabolism - cysteine and methionine; Hydrolase; EC 3.3.1.1; Other Amino Acids Metabolism - selenoamino acid

Chromosomal Location of Human Ortholog: 1p13.2

Cellular Component: endoplasmic reticulum; cytosol

Molecular Function: protein binding; adenosylhomocysteinase activity

Biological Process: S-adenosylmethionine cycle; regulation of ion transmembrane transporter activity; mRNA polyadenylation; one-carbon compound metabolic process; protein export from nucleus; regulation of mRNA 3'-end processing
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 Research Articles on AHCYL1    1. IRBIT is a master regulator of ion channels and ion transporters. (Review)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-AHCYL1 antibodyPathways associated with anti-AHCYL1 antibody
 Reference Product  PubMed Publications
 ITPR1 antibody  >1 publications with AHCYL1 and ITPR1
 DNMT3A antibody  >1 publications with AHCYL1 and DNMT3A
 DNMT1 antibody  >1 publications with AHCYL1 and DNMT1
 DNMT3B antibody  >1 publications with AHCYL1 and DNMT3B
 BHMT antibody  >1 publications with AHCYL1 and BHMT
 Products by Pathway  Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Cysteine And Methionine Metabolism Pathway antibodies  Cysteine And Methionine Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Methionine Degradation Pathway antibodies  Methionine Degradation Pathway Diagram
 Methionine Degradation Pathway antibodies  Methionine Degradation Pathway Diagram
 Trans-sulfuration And One Carbon Metabolism Pathway antibodies  Trans-sulfuration And One Carbon Metabolism Pathway Diagram
 Cysteine Biosynthesis III (mammalia) Pathway antibodies  Cysteine Biosynthesis III (mammalia) Pathway Diagram
 Methionine Degradation I (to Homocysteine) Pathway antibodies  Methionine Degradation I (to Homocysteine) Pathway Diagram
 Superpathway Of Methionine Degradation antibodies  Superpathway Of Methionine Degradation Diagram
Diseases associated with anti-AHCYL1 antibodyOrgans/Tissues associated with anti-AHCYL1 antibody
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >2 publications with AHCYL1 and Adenocarcinoma
 Carcinoma, Hepatocellular Antibodies  >1 publications with AHCYL1 and Carcinoma, Hepatocellular
 Ovarian Neoplasms Antibodies  >1 publications with AHCYL1 and Ovarian Neoplasms
 Liver Diseases Antibodies  >1 publications with AHCYL1 and Liver Diseases
 Carcinoma Antibodies  >1 publications with AHCYL1 and Carcinoma
 Cell Transformation, Neoplastic Antibodies  >1 publications with AHCYL1 and Cell Transformation, Neoplastic
 Fibrosis Antibodies  >1 publications with AHCYL1 and Fibrosis
 Liver Neoplasms Antibodies  >1 publications with AHCYL1 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >2 publications with AHCYL1 and Liver
 Stomach Antibodies  >1 publications with AHCYL1 and Stomach
 Muscle Antibodies  >1 publications with AHCYL1 and Muscle
 Brain Antibodies  >1 publications with AHCYL1 and Brain
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