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anti-S100A6 antibody :: Rabbit S100 Calcium Binding Protein A6 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS617365 anti-S100A6 antibody
Unit / Price
0.25 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

S100 Calcium Binding Protein A6 (S100A6), Polyclonal Antibody

 Also Known As   

S100 Calcium Binding Protein A6 (Calcyclin, Prolactin Receptor Associated Protein)

 Product Synonym Names    Anti -S100 Calcium Binding Protein A6 (Calcyclin, Prolactin Receptor Associated Protein)
 Product Gene Name   

anti-S100A6 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 1; NC_000001.10 (153507076..153508717, complement). Location: 1q21
 OMIM    114110
 3D Structure    ModBase 3D Structure for P06703
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Bovine, Canine, Equine, Feline, Human, Mouse, Rat
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 Specificity    Recognizes human S100A6. Species Crossreactivity: Mouse, Rat, Bovine, Equine, Feline and Canine.
 Purity/Purification    Serum
Serum.
 Form/Format    Supplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA and 0.09% sodium azide.
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 Immunogen    Purified recombinant human S100A6 monomer expressed in E. coli. Cellular Localization: Cytoplasmic.
 Positive Control    Tonsil
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-S100A6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-S100A6 antibody

   S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein is also expressed in the antigen presenting cells such as the Langerhans cells in skin and interdigitating reticulum cells in the paracortex of lymph nodes.
 Product Categories/Family for anti-S100A6 antibody    Antibodies; Abs to Binding Proteins
 Applications Tested/Suitable for anti-S100A6 antibody   

Immunohistochemistry (IHC)

 Application Notes for anti-S100A6 antibody    Suitable for use in Immunohistochemistry.
Dilution: Immunohistology (Formalin/paraffin): 1:50-1:100 for 30min at RT. Staining of formalin-fixed tissues REQUIRES boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min. Optimal dilutions to be determined by the researcher.
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NCBI/Uniprot data below describe general gene information for S100A6. It may not necessarily be applicable to this product.
 NCBI GI #    12655153
 NCBI GeneID    6277
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 UniProt Primary Accession #    P06703 [Other Products]
 UniProt Secondary Accession #    Q5RHS4; D3DV39 [Other Products]
 UniProt Related Accession #    P06703 [Other Products]
 Molecular Weight    10,180 Da [Similar Products]
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 NCBI Official Full Name    S100 calcium binding protein A6
 NCBI Official Synonym Full Names    S100 calcium binding protein A6
 NCBI Official Symbol    S100A6 [Similar Products]
 NCBI Official Synonym Symbols   
2A9; PRA; 5B10; CABP; CACY
[Similar Products]
 NCBI Protein Information    protein S100-A6; MLN 4; calcyclin; OTTHUMP00000015472; growth factor-inducible protein 2A9; prolactin receptor-associated protein; S100 calcium-binding protein A6 (calcyclin)
 UniProt Protein Name    Protein S100-A6
 UniProt Synonym Protein Names   
Calcyclin; Growth factor-inducible protein 2A9; MLN 4; Prolactin receptor-associated protein; PRA; S100 calcium-binding protein A6
 Protein Family    Protein
 UniProt Gene Name    S100A6 [Similar Products]
 UniProt Synonym Gene Names    CACY [Similar Products]
 UniProt Entry Name    S10A6_HUMAN
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 NCBI Summary for S100A6    The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq]
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 UniProt Comments for S100A6    S100A6: May function as calcium sensor and contribute to cellular calcium signaling (Potential). May function by interacting with other proteins and indirectly play a role in the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative. Belongs to the S-100 family.

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: ruffle; extrinsic to internal side of plasma membrane; perinuclear region of cytoplasm; cytoplasm; nuclear envelope; nucleus; cytosol

Molecular Function: protein binding; protein homodimerization activity; zinc ion binding; ion transmembrane transporter activity; calcium ion binding; tropomyosin binding; calcium-dependent protein binding

Biological Process: positive regulation of fibroblast proliferation; axonogenesis; signal transduction
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 Research Articles on S100A6    1. In melanocytic neoplasms composed of small spindle cells, patchy S100A6 staining should not be interpreted as evidence of supporting a diagnosis of melanoma
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-S100A6 antibodyPathways associated with anti-S100A6 antibody
 Reference Product  PubMed Publications
 S100B antibody  >60 publications with S100A6 and S100B
 CACYBP antibody  >20 publications with S100A6 and CACYBP
 ANXA2 antibody  >3 publications with S100A6 and ANXA2
 SUGT1 antibody  >2 publications with S100A6 and SUGT1
 GAPDH antibody  >2 publications with S100A6 and GAPDH
 ANXA11 antibody  >1 publications with S100A6 and ANXA11
 Products by Pathway  Pathway Diagram
 Prostaglandin Synthesis And Regulation Pathway antibodies  Prostaglandin Synthesis And Regulation Pathway Diagram
Diseases associated with anti-S100A6 antibodyOrgans/Tissues associated with anti-S100A6 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >142 publications with S100A6 and Neoplasms
 Carcinoma Antibodies  >66 publications with S100A6 and Carcinoma
 Skin Diseases Antibodies  >36 publications with S100A6 and Skin Diseases
 Adenocarcinoma Antibodies  >26 publications with S100A6 and Adenocarcinoma
 Skin Neoplasms Antibodies  >22 publications with S100A6 and Skin Neoplasms
 Melanoma Antibodies  >21 publications with S100A6 and Melanoma
 Neoplasm Metastasis Antibodies  >18 publications with S100A6 and Neoplasm Metastasis
 Endocrine Gland Neoplasms Antibodies  >18 publications with S100A6 and Endocrine Gland Neoplasms
 Head and Neck Neoplasms Antibodies  >15 publications with S100A6 and Head and Neck Neoplasms
 Central Nervous System Diseases Antibodies  >13 publications with S100A6 and Central Nervous System Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >42 publications with S100A6 and Brain
 Skin Antibodies  >38 publications with S100A6 and Skin
 Muscle Antibodies  >31 publications with S100A6 and Muscle
 Lung Antibodies  >26 publications with S100A6 and Lung
 Blood Antibodies  >23 publications with S100A6 and Blood
 Liver Antibodies  >20 publications with S100A6 and Liver
 Ascites Antibodies  >15 publications with S100A6 and Ascites
 Stomach Antibodies  >14 publications with S100A6 and Stomach
 Vascular Antibodies  >14 publications with S100A6 and Vascular
 Intestine Antibodies  >14 publications with S100A6 and Intestine
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