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anti-S100A1 antibody :: Rabbit S100 calcium binding protein A1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS714729 anti-S100A1 antibody
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.15 mL  /  $500 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

S100 calcium binding protein A1 (S100A1), Polyclonal Antibody

 Also Known As   

Rabbit anti-human S100 calcium binding protein A1 polyclonal Antibody

 Product Synonym Names    S100 calcium binding protein A1; S100A1; S100; S100-alpha; S100A
 Product Gene Name   

anti-S100A1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    176940
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Immunogen    Human S100A1
 Storage Buffer    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7849-R
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 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-S100A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-S100A1 antibody   

ELISA (EIA), Western Blot (WB)

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NCBI/Uniprot data below describe general gene information for S100A1. It may not necessarily be applicable to this product.
 NCBI GI #    15680116
 NCBI GeneID    6271
 NCBI Accession #    AAH14392.1 [Other Products]
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 UniProt Secondary Accession #    Q5T7Y3; B2R5D9 [Other Products]
 UniProt Related Accession #    P23297 [Other Products]
 Molecular Weight    10,546 Da [Similar Products]
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 NCBI Official Full Name    S100 calcium binding protein A1
 NCBI Official Synonym Full Names    S100 calcium binding protein A1
 NCBI Official Symbol    S100A1 [Similar Products]
 NCBI Official Synonym Symbols   
S100; S100A; S100-alpha
[Similar Products]
 NCBI Protein Information    protein S100-A1; S100 alpha; S-100 protein alpha chain; S-100 protein subunit alpha; S100 calcium-binding protein A1; S100 protein, alpha polypeptide
 UniProt Protein Name    Protein S100-A1
 UniProt Synonym Protein Names   
S-100 protein alpha chain; S-100 protein subunit alpha; S100 calcium-binding protein A1
 Protein Family    Protein
 UniProt Gene Name    S100A1 [Similar Products]
 UniProt Synonym Gene Names    S100A [Similar Products]
 UniProt Entry Name    S10A1_HUMAN
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 NCBI Summary for S100A1    The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008]
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 UniProt Comments for S100A1    S100A1: Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Dimer of either two alpha chains, or two beta chains, or one alpha and one beta chain. Interacts with AGER and CAPZA1. Interacts with FKBP4. Interacts with RYR1 and RYR2. Highly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain. Belongs to the S-100 family.

Protein type: Endoplasmic reticulum; Calcium-binding

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: neuron projection; protein complex; sarcoplasmic reticulum; M band; nucleus; Z disc

Molecular Function: identical protein binding; protein binding; protein homodimerization activity; calcium ion binding; calcium-dependent protein binding; ATPase binding

Biological Process: substantia nigra development; negative regulation of transcription from RNA polymerase II promoter; regulation of heart contraction
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 Research Articles on S100A1    1. hypoxia-induced MiR-138 is an essential mediator of EC dysfunction via its ability to target the 3'UTR of S100A1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-S100A1 antibodyDiseases associated with anti-S100A1 antibody
 Reference Product  PubMed Publications
 S100B antibody  >92 publications with S100A1 and S100B
 S100A4 antibody  >39 publications with S100A1 and S100A4
 RYR1 antibody  >18 publications with S100A1 and RYR1
 S100P antibody  >16 publications with S100A1 and S100P
 GFAP antibody  >12 publications with S100A1 and GFAP
 TP53 antibody  >1 publications with S100A1 and TP53
 ATP2A2 antibody  >1 publications with S100A1 and ATP2A2
 ANXA6 antibody  >1 publications with S100A1 and ANXA6
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >49 publications with S100A1 and Cardiovascular Diseases
 Heart Diseases Antibodies  >42 publications with S100A1 and Heart Diseases
 Ischemia Antibodies  >17 publications with S100A1 and Ischemia
 Hypertrophy Antibodies  >16 publications with S100A1 and Hypertrophy
 Kidney Diseases Antibodies  >16 publications with S100A1 and Kidney Diseases
 Disease Models, Animal Antibodies  >16 publications with S100A1 and Disease Models, Animal
 Neoplasm Metastasis Antibodies  >15 publications with S100A1 and Neoplasm Metastasis
 Inflammation Antibodies  >10 publications with S100A1 and Inflammation
 Breast Neoplasms Antibodies  >9 publications with S100A1 and Breast Neoplasms
 Hyperplasia Antibodies  >5 publications with S100A1 and Hyperplasia
Organs/Tissues associated with anti-S100A1 antibody
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >99 publications with S100A1 and Muscle
 Heart Antibodies  >79 publications with S100A1 and Heart
 Brain Antibodies  >62 publications with S100A1 and Brain
 Skin Antibodies  >28 publications with S100A1 and Skin
 Kidney Antibodies  >21 publications with S100A1 and Kidney
 Embryonic Tissue Antibodies  >10 publications with S100A1 and Embryonic Tissue
 Lung Antibodies  >9 publications with S100A1 and Lung
 Connective Tissue Antibodies  >8 publications with S100A1 and Connective Tissue
 Bone Antibodies  >7 publications with S100A1 and Bone
 Eye Antibodies  >6 publications with S100A1 and Eye
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