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anti-S100A14 antibody :: Rabbit anti-Human S100A14 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7046551
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

S100A14, Polyclonal Antibody

★Popular Item★
 Also Known As   

S100A14 Antibody

 Product Synonym Names    Protein S100-A14; S100 calcium-binding protein A14; S114; S100A14; S100A15
 Product Gene Name   

anti-S100A14 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    607986
 3D Structure    ModBase 3D Structure for Q9HCY8
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human Protein S100-A14 protein (1-104AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-S100A14 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-S100A14 antibody

   Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.
 Applications Tested/Suitable for anti-S100A14 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-S100A14 antibody    Western blot
All lanes: S100A14 antibody at 4.11 ug/ml+ A431 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 12 kDa
Observed band size: 12 kDa

anti-S100A14 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-S100A14 antibody    Immunohistochemistry of paraffin-embedded human colon cancer using MBS7046551 at dilution of 1:100
anti-S100A14 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-S100A14 antibody    Immunohistochemistry of paraffin-embedded human skin tissue using MBS7046551 at dilution of 1:100
anti-S100A14 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for S100A14. It may not necessarily be applicable to this product.
 NCBI GI #    10190712
 NCBI GeneID    57402
 NCBI Accession #    NP_065723.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_020672.2 [Other Products]
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 UniProt Primary Accession #    Q9HCY8 [Other Products]
 UniProt Secondary Accession #    Q5RHT0 [Other Products]
 UniProt Related Accession #    Q9HCY8 [Other Products]
 Molecular Weight    11,662 Da
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 NCBI Official Full Name    protein S100-A14
 NCBI Official Synonym Full Names    S100 calcium binding protein A14
 NCBI Official Symbol    S100A14 [Similar Products]
 NCBI Official Synonym Symbols   
BCMP84; S100A15
[Similar Products]
 NCBI Protein Information    protein S100-A14
 UniProt Protein Name    Protein S100-A14
 UniProt Synonym Protein Names   
S100 calcium-binding protein A14; S114
 Protein Family    Protein
 UniProt Gene Name    S100A14 [Similar Products]
 UniProt Synonym Gene Names    S100A15; S114 [Similar Products]
 UniProt Entry Name    S10AE_HUMAN
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 NCBI Summary for S100A14    This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828). [provided by RefSeq, Dec 2011]
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 UniProt Comments for S100A14    S100A14: a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828). [provided by RefSeq, Dec 2011]

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: cell junction; cytoplasm; microtubule cytoskeleton; nucleoplasm; perinuclear region of cytoplasm; plasma membrane

Molecular Function: chemokine receptor binding; protein binding

Biological Process: defense response to bacterium; response to lipopolysaccharide; toll-like receptor 4 signaling pathway
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 Research Articles on S100A14    1. Co-expression of S100A14 and S100A16 correlates with a poor prognosis in human breast cancer and promotes cancer cell invasion
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-S100A14 antibodyOrgans/Tissues associated with anti-S100A14 antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >10 publications with S100A14 and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >9 publications with S100A14 and Neoplasm Metastasis
 Adenocarcinoma Antibodies  >6 publications with S100A14 and Adenocarcinoma
 Cell Transformation, Neoplastic Antibodies  >3 publications with S100A14 and Cell Transformation, Neoplastic
 Inflammation Antibodies  >3 publications with S100A14 and Inflammation
 Liver Neoplasms Antibodies  >2 publications with S100A14 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >2 publications with S100A14 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >2 publications with S100A14 and Liver Diseases
 Fibrosis Antibodies  >1 publications with S100A14 and Fibrosis
 Neoplasms, Experimental Antibodies  >1 publications with S100A14 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Lymph Node Antibodies  >5 publications with S100A14 and Lymph Node
 Mouth Antibodies  >5 publications with S100A14 and Mouth
 Lung Antibodies  >3 publications with S100A14 and Lung
 Liver Antibodies  >2 publications with S100A14 and Liver
 Uterus Antibodies  >2 publications with S100A14 and Uterus
 Kidney Antibodies  >1 publications with S100A14 and Kidney
 Brain Antibodies  >1 publications with S100A14 and Brain
 Ovary Antibodies  >1 publications with S100A14 and Ovary
 Stomach Antibodies  >1 publications with S100A14 and Stomach
 Prostate Antibodies  >1 publications with S100A14 and Prostate
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