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anti-S100A4 antibody :: Rabbit anti-Human S100A4 / FSP1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS242231
Immunohistochemistry (IHC)
Unit / Price
0.25 mL  /  $530 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

S100A4 / FSP1, Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit Polyclonal to Human S100A4 / FSP1

 Product Synonym Names    Anti-S100A4 / FSP1 Antibody IHC-plus; S100A4; 42A; 18A2; Fibroblast-specific protein-1; FSP1; MTS1; PEL98; Protein Mts1; Calvasculin; CAPL; Metastasin; p9KA; Protein S100-A4; Human S100A4; FSP1
 Product Gene Name   

anti-S100A4 antibody

[Similar Products]
 Product Synonym Gene Name    FSP1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    114210
 3D Structure    ModBase 3D Structure for P26447
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Immunoaffinity Purified
 Form/Format    10 mM PBS, pH 7.4, BSA, sodium azide.
 Concentration    0.2 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Recombinant protein encoding full length human S100A4.
 Immunogen Type    Recombinant protein
 Immunogen    S100A4 / FSP1 antibody was raised against recombinant protein encoding full length human S100A4.
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 Preparation and Storage    +4 degree C or -20 degree C, Avoid repeated freezing and thawing.
 Other Notes    Small volumes of anti-S100A4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-S100A4 antibody

   S100 Calcium Binding Protein A4 (S100A4) is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. S100A4 may function in motility, invasion, and tubulin polymerization.
 Applications Tested/Suitable for anti-S100A4 antibody   

Immunohistochemistry (IHC - Paraffin)

 Application Notes for anti-S100A4 antibody    IHC-P (10 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
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 Immunohistochemistry (IHC) of anti-S100A4 antibody    Anti-S100A4 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-S100A4 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for S100A4. It may not necessarily be applicable to this product.
 NCBI GI #    9845516
 NCBI GeneID    6275
 NCBI Accession #    NP_062427.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_019554.2 [Other Products]
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 UniProt Primary Accession #    P26447 [Other Products]
 UniProt Secondary Accession #    Q6ICP8; A8K7R8; D3DV46 [Other Products]
 UniProt Related Accession #    P26447 [Other Products]
 Molecular Weight    11,729 Da
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 NCBI Official Full Name    protein S100-A4
 NCBI Official Synonym Full Names    S100 calcium binding protein A4
 NCBI Official Symbol    S100A4 [Similar Products]
 NCBI Official Synonym Symbols   
42A; 18A2; CAPL; FSP1; MTS1; P9KA; PEL98
[Similar Products]
 NCBI Protein Information    protein S100-A4; protein Mts1; fibroblast-specific protein-1; placental calcium-binding protein; malignant transformation suppression 1; leukemia multidrug resistance associated protein; S100 calcium-binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog)
 UniProt Protein Name    Protein S100-A4
 UniProt Synonym Protein Names   
Calvasculin; Metastasin; Placental calcium-binding protein; Protein Mts1; S100 calcium-binding protein A4
 Protein Family    Protein
 UniProt Gene Name    S100A4 [Similar Products]
 UniProt Synonym Gene Names    CAPL; MTS1 [Similar Products]
 UniProt Entry Name    S10A4_HUMAN
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 NCBI Summary for S100A4    The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
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 UniProt Comments for S100A4    S100A4: is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: extracellular space; neuron projection; perinuclear region of cytoplasm; nucleus

Molecular Function: identical protein binding; protein binding; RAGE receptor binding; calcium ion binding; actin binding; calcium-dependent protein binding

Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; epithelial to mesenchymal transition
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 Research Articles on S100A4    1. Patients with positive expression of S100A4 appear to have a poorer OS compared with those with negative expression of S100A4
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-S100A4 antibodyDiseases associated with anti-S100A4 antibody
 Reference Product  PubMed Publications
 ANXA2 antibody  >16 publications with S100A4 and ANXA2
 TP53 antibody  >10 publications with S100A4 and TP53
 MDM2 antibody  >8 publications with S100A4 and MDM2
 MYH9 antibody  >5 publications with S100A4 and MYH9
 CDK4 antibody  >3 publications with S100A4 and CDK4
 METAP2 antibody  >2 publications with S100A4 and METAP2
 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >224 publications with S100A4 and Neoplasm Metastasis
 Neoplasm Invasiveness Antibodies  >115 publications with S100A4 and Neoplasm Invasiveness
 Fibrosis Antibodies  >94 publications with S100A4 and Fibrosis
 Disease Models, Animal Antibodies  >90 publications with S100A4 and Disease Models, Animal
 Breast Neoplasms Antibodies  >89 publications with S100A4 and Breast Neoplasms
 Lung Diseases Antibodies  >76 publications with S100A4 and Lung Diseases
 Inflammation Antibodies  >61 publications with S100A4 and Inflammation
 Lung Neoplasms Antibodies  >43 publications with S100A4 and Lung Neoplasms
 Pancreatic Neoplasms Antibodies  >40 publications with S100A4 and Pancreatic Neoplasms
 Kidney Diseases Antibodies  >37 publications with S100A4 and Kidney Diseases
Organs/Tissues associated with anti-S100A4 antibody
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >132 publications with S100A4 and Muscle
 Blood Antibodies  >105 publications with S100A4 and Blood
 Vascular Antibodies  >102 publications with S100A4 and Vascular
 Lung Antibodies  >92 publications with S100A4 and Lung
 Bone Antibodies  >71 publications with S100A4 and Bone
 Lymph Node Antibodies  >66 publications with S100A4 and Lymph Node
 Liver Antibodies  >65 publications with S100A4 and Liver
 Kidney Antibodies  >62 publications with S100A4 and Kidney
 Brain Antibodies  >45 publications with S100A4 and Brain
 Embryonic Tissue Antibodies  >37 publications with S100A4 and Embryonic Tissue
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