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anti-S100A9 antibody :: Goat S100A9 / MRP14 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS242631
Unit / Price
0.05 mg  /  $530 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

S100A9 / MRP14, Polyclonal Antibody

 Also Known As   

Goat Polyclonal to Human S100A9 / MRP14

 Product Synonym Names    Anti-S100A9 / MRP14 Antibody (Internal) IHC-plus; S100A9; 60B8AG; Calgranulin B; CFAG; CAGB; Calgranulin-B; Calprotectin L1H subunit; CGLB; L1Ag; MRP14; NIF; p14; Protein S100-A9; LIAG; MAC387; MRP-14; Human S100A9; MRP14
 Product Gene Name   

anti-S100A9 antibody

[Similar Products]
 Product Synonym Gene Name    MRP14 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    123886
 3D Structure    ModBase 3D Structure for P06702
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Gibbon, Gorilla, Human
Predicted Reactivity: Monkey, Bovine, Hamster, Horse, Pig, Rabbit (at least 90% immunogen sequence identity)
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 Specificity    Human S100A9.
 Purity/Purification    Immunoaffinity Purified
 Form/Format    Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
 Concentration    0.5 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Synthetic peptide C-DTNADKQLSFEEF from an internal region of human S100A9 (NP_002956.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Hamster, Bovine, Rabbit, Horse, Pig (92%); Panda (85%).
 Immunogen Type    Synthetic peptide
 Immunogen    S100A9 / MRP14 antibody was raised against synthetic peptide C-DTNADKQLSFEEF from an internal region of human S100A9 (NP_002956.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Hamster, Bovine, Rabbit, Horse, Pig (92%); Panda (85%).
 Antigen Modification    Internal
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 Preparation and Storage    Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
 Other Notes    Small volumes of anti-S100A9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-S100A9 antibody

   Also known as S100 calcium-binding protein A9 and migration inhibitory factor-related protein 14.
 Applications Tested/Suitable for anti-S100A9 antibody   

Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)

 Application Notes for anti-S100A9 antibody    ELISA (1:8000, 0.3 - 1 ug/ml), IHC-P (2.5 ug/ml), WB (0.3 - 1 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
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 Immunohistochemistry (IHC) of anti-S100A9 antibody    Anti-S100A9 / MRP14 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
anti-S100A9 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-S100A9 antibody    Anti-S100A9 / MRP14 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
anti-S100A9 antibody Immunohistochemistry (IHC) (IHC) image
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 Western Blot (WB) of anti-S100A9 antibody    Antibody (0.5 ug/ml) staining of Human Peripheral Mononucleocytes lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-S100A9 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for S100A9. It may not necessarily be applicable to this product.
 NCBI GI #    4506773
 NCBI GeneID    6280
 NCBI Accession #    NP_002956.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002965.3 [Other Products]
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 UniProt Primary Accession #    P06702 [Other Products]
 UniProt Secondary Accession #    Q6FGA1; Q9NYM0; Q9UCJ1; D3DV36 [Other Products]
 UniProt Related Accession #    P06702 [Other Products]
 Molecular Weight    13,242 Da
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 NCBI Official Full Name    protein S100-A9
 NCBI Official Synonym Full Names    S100 calcium binding protein A9
 NCBI Official Symbol    S100A9 [Similar Products]
 NCBI Official Synonym Symbols   
MIF; NIF; P14; CAGB; CFAG; CGLB; L1AG; LIAG; MRP14; 60B8AG; MAC387
[Similar Products]
 NCBI Protein Information    protein S100-A9; MRP-14; calgranulin B; calgranulin-B; calprotectin L1H subunit; leukocyte L1 complex heavy chain; migration inhibitory factor-related protein 14; S100 calcium-binding protein A9 (calgranulin B)
 UniProt Protein Name    Protein S100-A9
 UniProt Synonym Protein Names   
Calgranulin-B; Calprotectin L1H subunit; Leukocyte L1 complex heavy chain; Migration inhibitory factor-related protein 14; MRP-14; p14; S100 calcium-binding protein A9
 Protein Family    Protein
 UniProt Gene Name    S100A9 [Similar Products]
 UniProt Synonym Gene Names    CAGB; CFAG; MRP14; MRP-14; p14 [Similar Products]
 UniProt Entry Name    S10A9_HUMAN
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 NCBI Summary for S100A9    The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis. This antimicrobial protein exhibits antifungal and antibacterial activity. [provided by RefSeq, Nov 2014]
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 UniProt Comments for S100A9    S100A9: a calcium-binding regulatory protein of the S-100 family expressed by macrophages in acutely inflammated tissues and in chronic inflammations. May be an inhibitor of protein kinases. Also expressed in epithelial cells constitutively or induced during dermatoses. May interact with components of the intermediate filaments in monocytes and epithelial cells. Interacts with CEACAM3 in a calcium-dependent manner.

Protein type: Calcium-binding

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: extracellular space; cytoskeleton; extracellular region; plasma membrane; nucleus; cytosol

Molecular Function: arachidonic acid binding; antioxidant activity; RAGE receptor binding; protein binding; signal transducer activity; zinc ion binding; microtubule binding; calcium ion binding

Biological Process: caspase activation; neutrophil chemotaxis; chemokine production; chronic inflammatory response; cytokine production; response to lipopolysaccharide; positive regulation of peptide secretion; signal transduction; positive regulation of cell growth; leukocyte migration during inflammatory response; activation of NF-kappaB transcription factor; sequestering of zinc ion; response to ethanol; cell-cell signaling; response to zinc ion; defense response to bacterium; actin cytoskeleton reorganization; autophagy; innate immune response; regulation of integrin biosynthetic process; inflammatory response; defense response to fungus; regulation of cytoskeleton organization and biogenesis; positive regulation of inflammatory response
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 Research Articles on S100A9    1. Expression of S100A9 and EGFR closely correlates with cisplatin chemoresistance in bladder cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-S100A9 antibodyDiseases associated with anti-S100A9 antibody
 Reference Product  PubMed Publications
 S100A8 antibody  >731 publications with S100A9 and S100A8
 S100A12 antibody  >86 publications with S100A9 and S100A12
 TLR4 antibody  >52 publications with S100A9 and TLR4
 MYD88 antibody  >9 publications with S100A9 and MYD88
 MAPK1 antibody  >4 publications with S100A9 and MAPK1
 PARP1 antibody  >2 publications with S100A9 and PARP1
 TIRAP antibody  >2 publications with S100A9 and TIRAP
 IRAK1 antibody  >1 publications with S100A9 and IRAK1
 LY96 antibody  >1 publications with S100A9 and LY96
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >390 publications with S100A9 and Inflammation
 Skin Diseases Antibodies  >119 publications with S100A9 and Skin Diseases
 Disease Models, Animal Antibodies  >96 publications with S100A9 and Disease Models, Animal
 Lung Diseases Antibodies  >81 publications with S100A9 and Lung Diseases
 Nervous System Diseases Antibodies  >76 publications with S100A9 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >75 publications with S100A9 and Cardiovascular Diseases
 Necrosis Antibodies  >70 publications with S100A9 and Necrosis
 Carcinoma, Squamous Cell Antibodies  >50 publications with S100A9 and Carcinoma, Squamous Cell
 Fibrosis Antibodies  >48 publications with S100A9 and Fibrosis
 Brain Diseases Antibodies  >47 publications with S100A9 and Brain Diseases
Organs/Tissues associated with anti-S100A9 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >453 publications with S100A9 and Blood
 Skin Antibodies  >113 publications with S100A9 and Skin
 Lung Antibodies  >105 publications with S100A9 and Lung
 Vascular Antibodies  >86 publications with S100A9 and Vascular
 Brain Antibodies  >58 publications with S100A9 and Brain
 Bone Antibodies  >53 publications with S100A9 and Bone
 Liver Antibodies  >46 publications with S100A9 and Liver
 Muscle Antibodies  >44 publications with S100A9 and Muscle
 Bone Marrow Antibodies  >44 publications with S100A9 and Bone Marrow
 Kidney Antibodies  >39 publications with S100A9 and Kidney
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