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Add To Compare List anti-SAMHD1 antibody :: Rabbit anti-Human SAMHD1 Polyclonal Antibody Catalog # MBS668775 Unit / Price 0.025 mg / $185 +1 FREE 8GB USB 0.1 mg / $340 +1 FREE 8GB USB 5x0.1 mg / $1,380 +1 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name SAMHD1, Polyclonal Antibody Full Product Name Polyclonal Antibody to SAMHD1 Product Synonym Names SAMHD1; MOP5; Dendritic cell-derived IFNG-induced protein; MOP-5, Monocyte protein 5; SAM domain and HD domain-containing protein 1; Antibody to SAMHD1; Anti-SAMHD1 Antibody; SAMHD1 Antibody Product Gene Name anti-SAMHD1 antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM AF228421 mRNA 3D Structure ModBase 3D Structure for Q9Y3Z3 Clonality Polyclonal Isotype IgG Host Rabbit Species Reactivity Human Purity/Purification PurifiedProtein A Chromatography Form/Format 25 ug in 50 ul/100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. Immunogen Information A partial length recombinant SAMHD1 protein (amino acids 380-520) was used as the immunogen for this antibody. Antigen SAMHD1 Preparation and Storage Store the antibody at 4 degree C, stable for 6 months.For long-term storage, store at -20 degree C.Avoid repeated freeze and thaw cycles. Other Notes Small volumes of anti-SAMHD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Product Categories/Family for anti-SAMHD1 antibody Antibodies; Immunology Applications Tested/Suitable for anti-SAMHD1 antibody Western Blot (WB) Application Notes for anti-SAMHD1 antibody WB: 2-4 ug/ml Western Blot (WB) of anti-SAMHD1 antibody Fig-1: Western blot analysis of SAMHD1. Anti-SAMHD1 antibody (11-4052) was used at 4 ug/ml on Liver lysate. TOP NCBI/Uniprot data below describe general gene information for SAMHD1. It may not necessarily be applicable to this product. NCBI GI # 22257047 NCBI GeneID 25939 NCBI Accession # Q9Y3Z3.2 [Other Products] UniProt Primary Accession # Q9Y3Z3 [Other Products] UniProt Secondary Accession # Q5JXG8; Q8N491; Q9H004; Q9H005; Q9H3U9; B4E2A5; E1P5V2[Other Products] UniProt Related Accession # Q9Y3Z3[Other Products] Molecular Weight 68,122 Da TOP NCBI Official Full Name Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 NCBI Official Synonym Full Names SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 NCBI Official Symbol SAMHD1 [Similar Products] NCBI Official Synonym Symbols DCIP; CHBL2; HDDC1; MOP-5; SBBI88 [Similar Products] NCBI Protein Information deoxynucleoside triphosphate triphosphohydrolase SAMHD1 UniProt Protein Name Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 UniProt Synonym Protein Names Dendritic cell-derived IFNG-induced protein; DCIP; Monocyte protein 5; MOP-5; SAM domain and HD domain-containing protein 1 Protein Family Deoxynucleoside triphosphate triphosphohydrolase UniProt Gene Name SAMHD1 [Similar Products] UniProt Synonym Gene Names MOP5; dNTPase; DCIP; MOP-5 [Similar Products] TOP NCBI Summary for SAMHD1 This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010] TOP UniProt Comments for SAMHD1 SAMHD1: a protein induced by interferon gamma.Protein type: EC 3.1.4.-Chromosomal Location of Human Ortholog: 20q11.23Cellular Component: nucleoplasm; nucleus; plasma membraneMolecular Function: dGTP binding; dGTPase activity; nucleic acid binding; protein binding; RNA binding; zinc ion bindingBiological Process: dATP catabolic process; defense response to virus; dGTP catabolic process; protein homotetramerization; regulation of innate immune responseDisease: Aicardi-goutieres Syndrome 5; Chilblain Lupus 2 Research Articles on SAMHD1 1. This study reviewed that Neurologic Phenotypes Associated with Mutations in SAMHD1 in patients with Aicardi-Goutieres Syndrome. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. 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TOP Pathways associated with anti-SAMHD1 antibody Products by Pathway Pathway Diagram Cytokine Signaling In Immune System Pathway antibodies Cytokine Signaling In Immune System Pathway Diagram Immune System Pathway antibodies Immune System Pathway Diagram Interferon Signaling Pathway antibodies Interferon Signaling Pathway Diagram Interferon Alpha/beta Signaling Pathway antibodies Interferon Alpha/beta Signaling Pathway Diagram Diseases associated with anti-SAMHD1 antibody Disease Name Pubmed Publications Aicardi-Goutieres syndrome Antibodies >63 publications with SAMHD1 and Aicardi-Goutieres syndrome Nervous System Diseases Antibodies >47 publications with SAMHD1 and Nervous System Diseases Brain Diseases Antibodies >15 publications with SAMHD1 and Brain Diseases Inflammation Antibodies >9 publications with SAMHD1 and Inflammation Aicardi-Goutieres syndrome 5 Antibodies >8 publications with SAMHD1 and Aicardi-Goutieres syndrome 5 Necrosis Antibodies >5 publications with SAMHD1 and Necrosis Hemorrhage Antibodies >4 publications with SAMHD1 and Hemorrhage Liver Diseases Antibodies >2 publications with SAMHD1 and Liver Diseases Adenocarcinoma Antibodies >2 publications with SAMHD1 and Adenocarcinoma Fetal Growth Retardation Antibodies >1 publications with SAMHD1 and Fetal Growth Retardation Organs/Tissues associated with anti-SAMHD1 antibody Organ/Tissue Name Pubmed Publications Blood Antibodies >76 publications with SAMHD1 and Blood Brain Antibodies >13 publications with SAMHD1 and Brain Vascular Antibodies >10 publications with SAMHD1 and Vascular Skin Antibodies >7 publications with SAMHD1 and Skin Lung Antibodies >6 publications with SAMHD1 and Lung Ganglia Antibodies >5 publications with SAMHD1 and Ganglia Liver Antibodies >5 publications with SAMHD1 and Liver Lymph Antibodies >4 publications with SAMHD1 and Lymph Lymph Node Antibodies >4 publications with SAMHD1 and Lymph Node Eye Antibodies >4 publications with SAMHD1 and Eye TOP © 2006-24 MyBioSource.com. 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