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anti-SAR1A antibody :: Rabbit anti-Human, Mouse SAR1A Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7044392
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SAR1A, Polyclonal Antibody

★Popular Item★
 Also Known As   

SAR1A Antibody

 Product Synonym Names    GTP-binding protein SAR1a; COPII-associated small GTPase; SAR1A; SAR1; SARA; SARA1
 Product Gene Name   

anti-SAR1A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    607691
 3D Structure    ModBase 3D Structure for Q9NR31
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human GTP-binding protein SAR1a protein (1-198AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-SAR1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SAR1A antibody

   Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).
 Applications Tested/Suitable for anti-SAR1A antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-SAR1A antibody    Western blot
All lanes: SAR1A antibody at 4.57ug/ml
Lane 1: Mouse lung tissue
Lane 2: NIH/3T3 whole cell lysate
Lane 3: A431 whole cell lysate
Lane 4: MCF7 whole cell lysate
Lane 5: Jurkat whole cell lysate
Lane 6: HepG-2 whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 23,18 kDa
Observed band size: 22 kDa

anti-SAR1A antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-SAR1A antibody    Immunohistochemistry of paraffin-embedded human liver tissue using MBS7044392 at dilution 1:100
anti-SAR1A antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-SAR1A antibody    Immunohistochemistry of paraffin-embedded human small intestine tissue using MBS7044392 at dilution 1:100
anti-SAR1A antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for SAR1A. It may not necessarily be applicable to this product.
 NCBI GI #    217416369
 NCBI GeneID    56681
 NCBI Accession #    NP_001136120.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001142648.1 [Other Products]
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 UniProt Primary Accession #    Q9NR31 [Other Products]
 UniProt Secondary Accession #    B4DQ19 [Other Products]
 UniProt Related Accession #    Q9NR31 [Other Products]
 Molecular Weight    17,500 Da
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 NCBI Official Full Name    GTP-binding protein SAR1a
 NCBI Official Synonym Full Names    secretion associated Ras related GTPase 1A
 NCBI Official Symbol    SAR1A [Similar Products]
 NCBI Official Synonym Symbols   
SAR1; Sara; SARA1; masra2
[Similar Products]
 NCBI Protein Information    GTP-binding protein SAR1a
 UniProt Protein Name    GTP-binding protein SAR1a
 UniProt Synonym Protein Names   
COPII-associated small GTPase
 Protein Family    GTP-binding protein
 UniProt Gene Name    SAR1A [Similar Products]
 UniProt Synonym Gene Names    SAR1; SARA; SARA1 [Similar Products]
 UniProt Entry Name    SAR1A_HUMAN
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 UniProt Comments for SAR1A    SAR1A: Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES). Belongs to the small GTPase superfamily. SAR1 family.

Protein type: G protein, monomeric; G protein, monomeric, SAR1; G protein

Chromosomal Location of Human Ortholog: 10q22.1
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 Research Articles on SAR1A    1. Data indicate that hydroxyurea (HU) induces SAR1 protein expression, which in turn activates gamma-globin expression, predominantly through the Gialpha/JNK/Jun pathway.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-SAR1A antibodyDiseases associated with anti-SAR1A antibody
 Products by Pathway  Pathway Diagram
 COPII Complex Pathway antibodies  COPII Complex Pathway Diagram
 COPII Complex Pathway antibodies  COPII Complex Pathway Diagram
 Legionellosis Pathway antibodies  Legionellosis Pathway Diagram
 Legionellosis Pathway antibodies  Legionellosis Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 SREBP Signalling Pathway antibodies  SREBP Signalling Pathway Diagram
 Disease Name  Pubmed Publications
 Anemia Antibodies  >1 publications with SAR1A and Anemia
 Fibrosis Antibodies  >1 publications with SAR1A and Fibrosis
 Heart Diseases Antibodies  >1 publications with SAR1A and Heart Diseases
Organs/Tissues associated with anti-SAR1A antibody
 Organ/Tissue Name  Pubmed Publications
 Pituitary Gland Antibodies  >4 publications with SAR1A and Pituitary Gland
 Blood Antibodies  >4 publications with SAR1A and Blood
 Brain Antibodies  >4 publications with SAR1A and Brain
 Heart Antibodies  >3 publications with SAR1A and Heart
 Vascular Antibodies  >2 publications with SAR1A and Vascular
 Kidney Antibodies  >2 publications with SAR1A and Kidney
 Pancreas Antibodies  >2 publications with SAR1A and Pancreas
 Lung Antibodies  >2 publications with SAR1A and Lung
 Liver Antibodies  >1 publications with SAR1A and Liver
 Intestine Antibodies  >1 publications with SAR1A and Intestine
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