NP_006355.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
protein transport protein Sec23A
NCBI Official Synonym Full Names
Sec23 homolog A, coat complex II component
NCBI Official Synonym Symbols
NCBI Protein Information
protein transport protein Sec23A
UniProt Protein Name
Protein transport protein Sec23A
UniProt Synonym Protein Names
SEC23-related protein A
UniProt Entry Name
SC23A_HUMAN
NCBI Summary for SEC23A
The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It is part of a protein complex and found in the ribosome-free transitional face of the endoplasmic reticulum (ER) and associated vesicles. This protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The encoded protein is suggested to play a role in the ER-Golgi protein trafficking. [provided by RefSeq, Jul 2008]
UniProt Comments for SEC23A
SEC23A: Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex. COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1. Interacts with SEC23IP. Interacts with HTR4. Interacts with SLC6A4. Interacts with SEC16A. Belongs to the SEC23/SEC24 family. SEC23 subfamily.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 14q21.1
Cellular Component: COPII vesicle coat; cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; Golgi membrane; perinuclear region of cytoplasm; smooth endoplasmic reticulum membrane
Molecular Function: protein binding; zinc ion binding
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; COPII coating of Golgi vesicle; ER to Golgi vesicle-mediated transport; intracellular protein transport; vesicle-mediated transport
Disease: Craniolenticulosutural Dysplasia
Research Articles on SEC23A
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Products associated with anti-SEC23A antibody
Pathways associated with anti-SEC23A antibody
Diseases associated with anti-SEC23A antibody
Organs/Tissues associated with anti-SEC23A antibody
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