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anti-SENP1 antibody :: Rabbit anti-Human, Mouse SENP1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS611921 anti-SENP1 antibody
Unit / Price
0.2 mL  /  $435 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SENP1, Polyclonal Antibody

 Also Known As   

SENP1 (Sentrin, SUMO-specific protease 1)

 Product Synonym Names    Anti -SENP1 (Sentrin, SUMO-specific protease 1)
 Product Gene Name   

anti-SENP1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 12; NC_000012.11 (48436757..48499641, complement). Location: 12q13.1
 3D Structure    ModBase 3D Structure for Q6N001
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Specificity    Recognizes human and mouse SENP1.
 Form/Format    Supplied as a liquid in PBS containing 0.2% gelatin and 0.05% sodium azide.
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 Immunogen    Synthetic peptide corresponding to aa 578-590 of human SENP1 (sentrin-specific protease 1).
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 Preparation and Storage    -20 degree C
 Other Notes    Small volumes of anti-SENP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-SENP1 antibody    Antibodies; Abs to Ubiquitin
 Applications Tested/Suitable for anti-SENP1 antibody   

Western Blot (WB)

 Application Notes for anti-SENP1 antibody    Western Blot (1:500-1:1'000)
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NCBI/Uniprot data below describe general gene information for SENP1. It may not necessarily be applicable to this product.
 NCBI GI #    7657550
 NCBI GeneID    29843
 NCBI Accession #    NP_055369.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_014554.2 [Other Products]
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 UniProt Primary Accession #    Q6N001 [Other Products]
 UniProt Related Accession #    Q6N001; Q7Z3G1; Q9P0U3 [Other Products]
 Molecular Weight    17,790 Da [Similar Products]
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 NCBI Official Full Name    sentrin-specific protease 1
 NCBI Official Synonym Full Names    SUMO1/sentrin specific peptidase 1
 NCBI Official Symbol    SENP1 [Similar Products]
 NCBI Official Synonym Symbols   
SuPr-2
[Similar Products]
 NCBI Protein Information    sentrin-specific protease 1; SUMO1/sentrin specific protease 1; sentrin/SUMO-specific protease SENP1
 UniProt Protein Name    Putative uncharacterized protein DKFZp686L1432
 Protein Family    Sentrin-specific protease
 UniProt Gene Name    DKFZp686L1432 [Similar Products]
 UniProt Synonym Gene Names    SENP1 [Similar Products]
 UniProt Entry Name    Q6N001_HUMAN
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 NCBI Summary for SENP1    The covalent modification of proteins by the small ubiquitin (UBB; MIM 191339)-like protein SUMO (see SUMO1, MIM 601912) is implicated in the regulation of nucleocytoplasmic transport, genomic stability, gene transcription, and other processes. Sumoylation is catalyzed on target lysine residues by a multienzyme process and is reversed by desumoylating enzymes such as SENP1 (Yamaguchi et al., 2005 [PubMed 15923632]).[supplied by OMIM]
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 UniProt Comments for SENP1    SENP1: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1, which decreases its transcriptional repression activity. Belongs to the peptidase C48 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protease; Nuclear receptor co-regulator; EC 3.4.22.68

Chromosomal Location of Human Ortholog: 12q13.1

Cellular Component: nucleoplasm; nuclear membrane; focal adhesion; cytoplasm; nucleus

Molecular Function: protein binding; endopeptidase activity; SUMO-specific protease activity

Biological Process: protein desumoylation; caspase activation; protein sumoylation; cellular protein metabolic process; positive regulation of transcription from RNA polymerase II promoter; proteolysis; post-translational protein modification; negative regulation of proteasomal ubiquitin-dependent protein catabolic process
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 Research Articles on SENP1    1. Could use the urinary hTERT, SENP1, PPP1CA, and MCM5 mRNA to detect bladder cancer recurrence.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to SENP1 (Sentrin, SUMO-specific protease 1)
 Catalog #  Product Name  Catalog #  Product Name
 MBS7051445  SENP1 Antibody  MBS612189  SENP1 (Sentrin, SUMO-specific protease 1)
 MBS7603945  SENP1 Rabbit Polyclonal  MBS9202497  SENP1 Antibody (N-term)
 MBS1425616  Recombinant Human Sentrin-specific protease 1 (SENP1)  MBS611921  SENP1 (Sentrin, SUMO-specific protease 1)
 MBS9219019  SENP1 Antibody (N-term) Blocking Peptide  MBS824415  SENP1 Blocking Peptide
 MBS2522295  SENP1 Polyclonal Antibody  MBS2526223  SENP1 Polyclonal Antibody
Products associated with anti-SENP1 antibodyPathways associated with anti-SENP1 antibody
 Reference Product  PubMed Publications
 HDAC1 antibody  >1 publications with SENP1 and HDAC1
 Products by Pathway  Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Regulation Of Androgen Receptor Activity Pathway antibodies  Regulation Of Androgen Receptor Activity Pathway Diagram
Diseases associated with anti-SENP1 antibodyOrgans/Tissues associated with anti-SENP1 antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >5 publications with SENP1 and Carcinoma
 Inflammation Antibodies  >2 publications with SENP1 and Inflammation
 Anemia Antibodies  >2 publications with SENP1 and Anemia
 Urinary Bladder Neoplasms Antibodies  >1 publications with SENP1 and Urinary Bladder Neoplasms
 Arthritis, Experimental Antibodies  >1 publications with SENP1 and Arthritis, Experimental
 Adenoma Antibodies  >1 publications with SENP1 and Adenoma
 Colorectal Neoplasms Antibodies  >1 publications with SENP1 and Colorectal Neoplasms
 Drug Toxicity Antibodies  >1 publications with SENP1 and Drug Toxicity
 Thyroid Neoplasms Antibodies  >1 publications with SENP1 and Thyroid Neoplasms
 Colonic Neoplasms Antibodies  >1 publications with SENP1 and Colonic Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >7 publications with SENP1 and Prostate
 Brain Antibodies  >6 publications with SENP1 and Brain
 Vascular Antibodies  >4 publications with SENP1 and Vascular
 Kidney Antibodies  >4 publications with SENP1 and Kidney
 Liver Antibodies  >3 publications with SENP1 and Liver
 Pancreas Antibodies  >2 publications with SENP1 and Pancreas
 Bone Antibodies  >2 publications with SENP1 and Bone
 Placenta Antibodies  >1 publications with SENP1 and Placenta
 Eye Antibodies  >1 publications with SENP1 and Eye
 Skin Antibodies  >1 publications with SENP1 and Skin
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