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anti-SERPINB3 antibody :: Rabbit anti-Human SERPINB3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS628628 anti-SERPINB3 antibody
Unit / Price
0.2 mL  /  $550 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SERPINB3, Polyclonal Antibody

★Popular Item★
 Also Known As   

SERPINB3, NT (Serpin B3, Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3, Squamous Cell Carcinoma Antigen 1, SCCA-1, Protein T4-A, SCCA1, SCCA, SPB3)

 Product Synonym Names    Anti -SERPINB3, NT (Serpin B3, Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3, Squamous Cell Carcinoma Antigen 1, SCCA-1, Protein T4-A, SCCA1, SCCA, SPB3)
 Product Gene Name   

anti-SERPINB3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 18; NC_000018.9 (61322431..61329197, complement). Location: 18q21.3
 OMIM    600517
 3D Structure    ModBase 3D Structure for P29508
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    Recognizes human SERPINB3.
 Purity/Purification    Purified
Purified by ammonium sulfate precipitation.
 Form/Format    Supplied as a liquid in PBS, 0.09% sodium azide.
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 Immunogen    Synthetic peptide corresponding to aa47-77 at the N-terminal region of human SERPINB3, conjugated to KLH.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
 Other Notes    Small volumes of anti-SERPINB3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SERPINB3 antibody

   SPB3 may act as a protease inhibitor to modulate the host immune response against tumor cells.
 Product Categories/Family for anti-SERPINB3 antibody    Antibodies; Abs to Protease Inhibitors
 Applications Tested/Suitable for anti-SERPINB3 antibody   

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)

 Application Notes for anti-SERPINB3 antibody    Suitable for use in ELISA, Western Blot, Immunohistochemistry and Flow Cytometry.
Dilution: ELISA: 1:1000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:50-1:100
Flow Cytometry: 1:10-1:50
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NCBI/Uniprot data below describe general gene information for SERPINB3. It may not necessarily be applicable to this product.
 NCBI GI #    5902072
 NCBI GeneID    6317
 NCBI Accession #    NP_008850.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006919.2 [Other Products]
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 UniProt Primary Accession #    P29508 [Other Products]
 UniProt Secondary Accession #    Q53H28; Q53YB5; Q86VF3; Q86W04; Q8IWL4; Q8IXI3; Q96J21; Q9BYF8; A6NDM2; B2RBT5 [Other Products]
 UniProt Related Accession #    P29508; Q5K634; Q5K684; Q9BYH9 [Other Products]
 Molecular Weight    44,565 Da [Similar Products]
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 NCBI Official Full Name    serpin B3
 NCBI Official Synonym Full Names    serpin peptidase inhibitor, clade B (ovalbumin), member 3
 NCBI Official Symbol    SERPINB3 [Similar Products]
 NCBI Official Synonym Symbols   
SCC; T4-A; SCCA1; SCCA-1; HsT1196; SCCA-PD
[Similar Products]
 NCBI Protein Information    serpin B3; protein T4-A; OTTHUMP00000066804; OTTHUMP00000066805; squamous cell carcinoma antigen 1; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3
 UniProt Protein Name    Serpin B3
 UniProt Synonym Protein Names   
Protein T4-A; Squamous cell carcinoma antigen 1
 Protein Family    Serpin
 UniProt Gene Name    SERPINB3 [Similar Products]
 UniProt Synonym Gene Names    SCCA; SCCA1 [Similar Products]
 UniProt Entry Name    SPB3_HUMAN
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 UniProt Comments for SERPINB3    SERPINB3: May act as a protease inhibitor to modulate the host immune response against tumor cells. Belongs to the serpin family. Ov-serpin subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 18q21.3

Cellular Component: extracellular space; cytoplasm; cytoplasmic vesicle; nucleus; vesicle

Molecular Function: viral receptor activity; serine-type endopeptidase inhibitor activity; protease binding; cysteine protease inhibitor activity

Biological Process: negative regulation of proteolysis; negative regulation of JNK activity; entry of virus into host cell; positive regulation of cell proliferation; negative regulation of catalytic activity; negative regulation of peptidase activity; positive regulation of cell migration
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 Research Articles on SERPINB3    1. In conclusion, the single amino acid substitution G351Ain the SERPINB3 reactive site loop improves the functional activity of the isoform.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-SERPINB3 antibodyDiseases associated with anti-SERPINB3 antibody
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Disease Name  Pubmed Publications
 Carcinoma, Squamous Cell Antibodies  >15 publications with SERPINB3 and Carcinoma, Squamous Cell
 Neoplasms Antibodies  >8 publications with SERPINB3 and Neoplasms
 Asthma Antibodies  >3 publications with SERPINB3 and Asthma
 Carcinoma, Hepatocellular Antibodies  >2 publications with SERPINB3 and Carcinoma, Hepatocellular
 Head and Neck Neoplasms Antibodies  >2 publications with SERPINB3 and Head and Neck Neoplasms
 Skin Neoplasms Antibodies  >2 publications with SERPINB3 and Skin Neoplasms
 Fibrosis Antibodies  >2 publications with SERPINB3 and Fibrosis
 Liver Neoplasms Antibodies  >1 publications with SERPINB3 and Liver Neoplasms
 Liver Neoplasms, Experimental Antibodies  >1 publications with SERPINB3 and Liver Neoplasms, Experimental
 Autoimmune Diseases Antibodies  >1 publications with SERPINB3 and Autoimmune Diseases
Organs/Tissues associated with anti-SERPINB3 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >8 publications with SERPINB3 and Blood
 Mouth Antibodies  >2 publications with SERPINB3 and Mouth
 Lung Antibodies  >2 publications with SERPINB3 and Lung
 Larynx Antibodies  >1 publications with SERPINB3 and Larynx
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