Q16585.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Beta-sarcoglycan
NCBI Official Synonym Full Names
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
NCBI Protein Information
beta-sarcoglycan; 43DAG; beta-SG; 43 kDa dystrophin-associated glycoprotein; limb girdle muscular dystrophy 2E (non-linked families); beta-sarcoglycan(43kD dystrophin-associated glycoprotein)
UniProt Protein Name
Beta-sarcoglycan
UniProt Synonym Protein Names
43 kDa dystrophin-associated glycoprotein; 43DAG; A3b
UniProt Synonym Gene Names
UniProt Entry Name
SGCB_HUMAN
NCBI Summary for SGCB
This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.[provided by RefSeq, Oct 2008]
UniProt Comments for SGCB
SGCB: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. Defects in SGCB are the cause of limb-girdle muscular dystrophy type 2E (LGMD2E). LGMD2E is an autosomal recessive disorder. Belongs to the sarcoglycan beta/delta/gamma/zeta family.
Protein type: Dystrophin complex; Membrane protein, integral
Chromosomal Location of Human Ortholog: 4q12
Cellular Component: dystrophin-associated glycoprotein complex; cytoskeleton; integral to plasma membrane; cytoplasm; sarcoglycan complex; sarcolemma
Biological Process: muscle development; cardiac muscle cell development; muscle fiber development
Disease: Muscular Dystrophy, Limb-girdle, Type 2e
Research Articles on SGCB
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Products associated with anti-SGCB antibody
Pathways associated with anti-SGCB antibody
Diseases associated with anti-SGCB antibody
Organs/Tissues associated with anti-SGCB antibody
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