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anti-SLC5A2 antibody :: SGLT2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS821113
Western Blot (WB)
Unit / Price
0.03 mL  /  $155 +1 FREE 8GB USB
0.1 mL  /  $220 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SGLT2 (SLC5A2), Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-SGLT2 Antibody

 Product Synonym Names    SGLT2; Sodium/glucose cotransporter 2; Na(+)/glucose cotransporter 2; Low affinity sodium-glucose cotransporter; Solute carrier family 5 member 2
 Product Gene Name   

anti-SLC5A2 antibody

[Similar Products]
 Antibody/Peptide Pairs    SGLT2 peptide (MBS823010) is used for blocking the activity of SGLT2 antibody (MBS821113)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    gene 233100
 3D Structure    ModBase 3D Structure for P31639
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 Clonality    Polyclonal
 Species Reactivity    Human, Mouse, Rat
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 Specificity    Recognizes endogenous levels of SGLT2 protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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 Source    Rabbit
 Entrez Gene    6524 (Human); 246787 (Mouse); 64522 (Rat)
 SwissProt    P31639 (Human); Q923I7 (Mouse); P53792 (Rat)
 Immunogen    KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SGLT2. The exact sequence is proprietary.
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 Preparation and Storage    Shipped at 4C. Upon delivery aliquot and store at -20C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-SLC5A2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SLC5A2 antibody

   Rabbit polyclonal antibody to SGLT2
 Applications Tested/Suitable for anti-SLC5A2 antibody   

Western Blot (WB)

 Application Notes for anti-SLC5A2 antibody    WB (1/500 - 1/1000)
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 Western Blot (WB) of anti-SLC5A2 antibody    Western blot analysis of SGLT2 expression in HeLa (A), SP2/0 (B), H9C2 (C) whole cell lysates.
anti-SLC5A2 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for SLC5A2. It may not necessarily be applicable to this product.
 NCBI GI #    4507033
 NCBI GeneID    6524
 NCBI Accession #    NP_003032.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003041.3 [Other Products]
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 UniProt Primary Accession #    P31639 [Other Products]
 UniProt Secondary Accession #    A2RRD2 [Other Products]
 UniProt Related Accession #    P31639 [Other Products]
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 NCBI Official Full Name    sodium/glucose cotransporter 2
 NCBI Official Synonym Full Names    solute carrier family 5 (sodium/glucose cotransporter), member 2
 NCBI Official Symbol    SLC5A2 [Similar Products]
 NCBI Official Synonym Symbols   
SGLT2
[Similar Products]
 NCBI Protein Information    sodium/glucose cotransporter 2; Na(+)/glucose cotransporter 2; solute carrier family 5 member 2; low affinity sodium-glucose cotransporter; solute carrier family 5 (sodium/glucose transporter), member 2
 UniProt Protein Name    Sodium/glucose cotransporter 2
 UniProt Synonym Protein Names   
Low affinity sodium-glucose cotransporter; Solute carrier family 5 member 2
 Protein Family    Sodium/glucose cotransporter
 UniProt Gene Name    SLC5A2 [Similar Products]
 UniProt Synonym Gene Names    SGLT2; Na(+)/glucose cotransporter 2 [Similar Products]
 UniProt Entry Name    SC5A2_HUMAN
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 NCBI Summary for SLC5A2    This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. [provided by RefSeq, Sep 2009]
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 UniProt Comments for SLC5A2    SLC5A2: Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1. Defects in SLC5A2 are the cause of renal glucosuria (GLYS1). GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.

Protein type: Transporter, SLC family; Transporter; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: plasma membrane; integral to membrane

Molecular Function: low-affinity glucose:sodium symporter activity

Biological Process: transport; carbohydrate metabolic process; sodium ion transport; glucose transport; transmembrane transport

Disease: Renal Glucosuria
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 Research Articles on SLC5A2    1. A single dose of canagliflozin, a sodium glucose co-transporter 2 inhibitor, 300 mg reduced both fasting and postprandial PG.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SLC5A2 antibodyPathways associated with anti-SLC5A2 antibody
 Reference Product  PubMed Publications
 SLC2A2 antibody  >2 publications with SLC5A2 and SLC2A2
 Products by Pathway  Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Glycogen Storage Diseases Pathway antibodies  Glycogen Storage Diseases Pathway Diagram
 Hexose Transport Pathway antibodies  Hexose Transport Pathway Diagram
 Inositol Transporters Pathway antibodies  Inositol Transporters Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Carbohydrates Pathway antibodies  Metabolism Of Carbohydrates Pathway Diagram
 Myoclonic Epilepsy Of Lafora Pathway antibodies  Myoclonic Epilepsy Of Lafora Pathway Diagram
 Na+-dependent Glucose Transporters Pathway antibodies  Na+-dependent Glucose Transporters Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
Diseases associated with anti-SLC5A2 antibodyOrgans/Tissues associated with anti-SLC5A2 antibody
 Disease Name  Pubmed Publications
 Glycosuria Antibodies  >50 publications with SLC5A2 and Glycosuria
 Glycosuria, Renal Antibodies  >41 publications with SLC5A2 and Glycosuria, Renal
 Kidney Diseases Antibodies  >34 publications with SLC5A2 and Kidney Diseases
 Weight Loss Antibodies  >14 publications with SLC5A2 and Weight Loss
 Inflammation Antibodies  >7 publications with SLC5A2 and Inflammation
 Cardiovascular Diseases Antibodies  >6 publications with SLC5A2 and Cardiovascular Diseases
 Hypertension Antibodies  >5 publications with SLC5A2 and Hypertension
 Death Antibodies  >5 publications with SLC5A2 and Death
 Polyuria Antibodies  >3 publications with SLC5A2 and Polyuria
 Hypertrophy Antibodies  >2 publications with SLC5A2 and Hypertrophy
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >93 publications with SLC5A2 and Kidney
 Pancreas Antibodies  >7 publications with SLC5A2 and Pancreas
 Intestine Antibodies  >5 publications with SLC5A2 and Intestine
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