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anti-SGSM2 antibody :: Rabbit SGSM2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS151080
Unit / Price
0.1 mg  /  $365 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SGSM2, Polyclonal Antibody

★Popular Item★
 Also Known As   

SGSM2 Antibody

 Product Synonym Names    SGSM2; RUTBC1; KIAA0397; RUTBC1; Small G protein signaling modulator 2; RUN and TBC1 domain-containing protein 1; small G protein signaling modulator 2
 Product Gene Name   

anti-SGSM2 antibody

[Similar Products]
 Antibody/Peptide Pairs    SGSM2 peptide (MBS152368) is used for blocking the activity of SGSM2 antibody (MBS151080)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    611418
 3D Structure    ModBase 3D Structure for O43147
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    Multiple isoforms of SGSM2 are known to exist. SGSM2 antibody is predicted to not cross react with other SGSM family proteins.
 Purity/Purification    SGSM2 Antibody is affinity chromatography purified via peptide column.
 Form/Format    Liquid
 Concentration    1 mg/mL (lot specific)
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 Conjugate    Unconjugated
 Immunogen    SGSM2 antibody was raised against an 18 amino acid synthetic peptide near the center of human SGSM2.
 Buffer    SGSM2 Antibody is supplied in PBS containing 0.02% sodium azide.
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 Preparation and Storage    SGSM2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
 Other Notes    Small volumes of anti-SGSM2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SGSM2 antibody

   SGSM2 Antibody: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM2 is a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins.
 Applications Tested/Suitable for anti-SGSM2 antibody   

ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

 Application Notes for anti-SGSM2 antibody    SGSM2 antibody can be used for detection of SGSM2 by Western blot at 1 mug/mL. For immunofluorescence start at 20 mug/mL.
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 Western Blot (WB) of anti-SGSM2 antibody    Western blot analysis of SGSM2 in human cerebellum tissue lysate with SGSM2 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide
anti-SGSM2 antibody Western Blot (WB) (WB) image
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 Immunofluorescence (IF) of anti-SGSM2 antibody    Immunofluorescence of SGSM2 in human brain tissue with SGSM2 antibody at 20 μg/mL.
anti-SGSM2 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for SGSM2. It may not necessarily be applicable to this product.
 NCBI GI #    148612795
 NCBI GeneID    9905
 NCBI Accession #    NP_055668 [Other Products]
 NCBI GenBank Nucleotide #    NM_014853.2 [Other Products]
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 UniProt Primary Accession #    O43147 [Other Products]
 UniProt Secondary Accession #    Q49AC2; Q6ZUY2; Q8IXU4; A5LGW2; B4DH69 [Other Products]
 UniProt Related Accession #    O43147 [Other Products]
 Molecular Weight    116 kDa
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 NCBI Official Full Name    small G protein signaling modulator 2 isoform 1
 NCBI Official Synonym Full Names    small G protein signaling modulator 2
 NCBI Official Symbol    SGSM2 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    small G protein signaling modulator 2; RUN and TBC1 domain containing 1; RUN and TBC1 domain-containing protein 1; small G protein signaling modulator 2 protein
 UniProt Protein Name    Small G protein signaling modulator 2
 UniProt Synonym Protein Names   
RUN and TBC1 domain-containing protein 1
 Protein Family    Small G protein signaling modulator
 UniProt Gene Name    SGSM2 [Similar Products]
 UniProt Synonym Gene Names    KIAA0397; RUTBC1 [Similar Products]
 UniProt Entry Name    SGSM2_HUMAN
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 UniProt Comments for SGSM2    SGSM2: Belongs to the RUTBC family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein regulator, misc.

Chromosomal Location of Human Ortholog: 17p13.3

Molecular Function: Rab GTPase binding
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 Research Articles on SGSM2    1. RUTBC1 is a Tre2/Bub2/Cdc16 domain-containing protein that binds to Rab9A-GTP both in vitro and in cultured cells, but is not a GTPase-activating protein for Rab9A.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SGSM2 antibodyDiseases associated with anti-SGSM2 antibody
 Reference Product  PubMed Publications
 SGSM3 antibody  >1 publications with SGSM2 and SGSM3
 Disease Name  Pubmed Publications
 Atherosclerosis Antibodies  >1 publications with SGSM2 and Atherosclerosis
 Insulin Resistance Antibodies  >1 publications with SGSM2 and Insulin Resistance
Organs/Tissues associated with anti-SGSM2 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3 publications with SGSM2 and Blood
 Heart Antibodies  >2 publications with SGSM2 and Heart
 Testis Antibodies  >1 publications with SGSM2 and Testis
 Brain Antibodies  >1 publications with SGSM2 and Brain
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