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anti-SH3GL2 antibody :: Rabbit anti-Human SH3GL2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7044564
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SH3GL2, Polyclonal Antibody

★Popular Item★
 Also Known As   

SH3GL2 Antibody

 Product Synonym Names    Endophilin-A1; EEN-B1; Endophilin-1; SH3 domain protein 2A; SH3 domain-containing GRB2-like protein 2; SH3GL2; CNSA2; SH3D2A
 Product Gene Name   

anti-SH3GL2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    604465
 3D Structure    ModBase 3D Structure for Q99962
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human Endophilin-A1 protein (N-270AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-10875 / sc-10874 / sc-8907
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-SH3GL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SH3GL2 antibody

   Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature.
 Applications Tested/Suitable for anti-SH3GL2 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-SH3GL2 antibody    Western blot
All lanes: SH3GL2 antibody at 0.91ug/ml
Lane 1:Hela whole cell lysate
Lane 2:293T whole cell lysate
Lane 3:HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 40kDa
Observed band size: 40kDa

anti-SH3GL2 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-SH3GL2 antibody    Immunohistochemistry of paraffin-embedded human brain tissue using MBS7044564 at dilution 1:100
anti-SH3GL2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for SH3GL2. It may not necessarily be applicable to this product.
 NCBI GI #    4506931
 NCBI GeneID    6456
 NCBI Accession #    NP_003017.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003026.3 [Other Products]
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 UniProt Primary Accession #    Q99962 [Other Products]
 UniProt Secondary Accession #    Q9NQK5; B2R618 [Other Products]
 UniProt Related Accession #    Q99962 [Other Products]
 Molecular Weight    39,962 Da
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 NCBI Official Full Name    endophilin-A1
 NCBI Official Synonym Full Names    SH3 domain containing GRB2 like 2, endophilin A1
 NCBI Official Symbol    SH3GL2 [Similar Products]
 NCBI Official Synonym Symbols   
CNSA2; SH3P4; EEN-B1; SH3D2A
[Similar Products]
 NCBI Protein Information    endophilin-A1
 UniProt Protein Name    Endophilin-A1
 UniProt Synonym Protein Names   
EEN-B1; Endophilin-1; SH3 domain protein 2A; SH3 domain-containing GRB2-like protein 2
 Protein Family    Endophilin
 UniProt Gene Name    SH3GL2 [Similar Products]
 UniProt Synonym Gene Names    CNSA2; SH3D2A [Similar Products]
 UniProt Entry Name    SH3G2_HUMAN
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 UniProt Comments for SH3GL2    endophilin 1: Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Belongs to the endophilin family.

Protein type: Membrane protein, peripheral; Adaptor/scaffold; Vesicle

Chromosomal Location of Human Ortholog: 9p22

Cellular Component: cytosol; Golgi membrane; plasma membrane

Molecular Function: identical protein binding; protein binding

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; central nervous system development; microtubule-based movement; negative regulation of epidermal growth factor receptor signaling pathway; signal transduction
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 Research Articles on SH3GL2    1. Endophilin-1 positively regulated blood-brain barrier permeability via the EGFR-JNK signaling pathway in hCMEC/D3 cells, which would provide an experimental basis for further research on endophilin-1 mediated the opening of blood-brain barrier .
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SH3GL2 antibodyPathways associated with anti-SH3GL2 antibody
 Reference Product  PubMed Publications
 EGFR antibody  >10 publications with SH3GL2 and EGFR
 CBL antibody  >8 publications with SH3GL2 and CBL
 SH3KBP1 antibody  >7 publications with SH3GL2 and SH3KBP1
 PDCD6IP antibody  >4 publications with SH3GL2 and PDCD6IP
 SYNJ1 antibody  >2 publications with SH3GL2 and SYNJ1
 AMPH antibody  >1 publications with SH3GL2 and AMPH
 DNM1 antibody  >1 publications with SH3GL2 and DNM1
 DNM2 antibody  >1 publications with SH3GL2 and DNM2
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Clathrin Derived Vesicle Budding Pathway antibodies  Clathrin Derived Vesicle Budding Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 EGFR Downregulation Pathway antibodies  EGFR Downregulation Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Golgi Associated Vesicle Biogenesis Pathway antibodies  Golgi Associated Vesicle Biogenesis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
Diseases associated with anti-SH3GL2 antibodyOrgans/Tissues associated with anti-SH3GL2 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >7 publications with SH3GL2 and Nervous System Diseases
 Death Antibodies  >3 publications with SH3GL2 and Death
 Cell Transformation, Neoplastic Antibodies  >2 publications with SH3GL2 and Cell Transformation, Neoplastic
 Disease Models, Animal Antibodies  >2 publications with SH3GL2 and Disease Models, Animal
 Immune System Diseases Antibodies  >2 publications with SH3GL2 and Immune System Diseases
 Adenocarcinoma Antibodies  >2 publications with SH3GL2 and Adenocarcinoma
 Hyperplasia Antibodies  >1 publications with SH3GL2 and Hyperplasia
 Neurobehavioral Manifestations Antibodies  >1 publications with SH3GL2 and Neurobehavioral Manifestations
 Kidney Diseases Antibodies  >1 publications with SH3GL2 and Kidney Diseases
 Nerve Degeneration Antibodies  >1 publications with SH3GL2 and Nerve Degeneration
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >23 publications with SH3GL2 and Brain
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