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anti-SKOR2 antibody :: Rabbit anti-Human SKOR2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9204741
Western Blot (WB)
Unit / Price
0.08 mL  /  $155 +1 FREE 8GB USB
0.4 mL  /  $340 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SKOR2, Polyclonal Antibody

★Popular Item★
 Also Known As   

SKOR2 Antibody (C-term)

 Product Synonym Names    SKI family transcriptional corepressor 2; Functional Smad-suppressing element on chromosome 18; Fussel-18; LBX1 corepressor 1-like protein; Ladybird homeobox corepressor 1-like protein; SKOR2; CORL2; FUSSEL18
 Product Gene Name   

anti-SKOR2 antibody

[Similar Products]
 Antibody/Peptide Pairs    SKOR2 peptide (MBS9229632) is used for blocking the activity of SKOR2 antibody (MBS9204741)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q2VWA4
 Clonality    Polyclonal
 Isotype    Rabbit Ig
 Clone Number    RB51023
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    This SKOR2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 741-775 amino acids from the C-terminal region of human SKOR2.
 Purity/Purification    Purified Rabbit Polyclonal Antibody (Pab)
 Form/Format    Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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 Cellular Location    Nucleus.Cytoplasm
 Tissue Location    Expressed in cerebellum, spinal cord and testis. Isoform 2 is present in cerebellum (at protein level)
    
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 Preparation and Storage    Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
 Other Notes    Small volumes of anti-SKOR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-SKOR2 antibody

   Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system.
 Product Categories/Family for anti-SKOR2 antibody    Neuroscience; Signal Transduction
 Applications Tested/Suitable for anti-SKOR2 antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-SKOR2 antibody    WB~~1:1000
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 Western Blot (WB) of anti-SKOR2 antibody    Western blot analysis of lysates from human cerebellum, human testis, mouse cerebellum tissue lysate (from left to right), using SKOR2 Antibody (C-term). MBS9204741 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
anti-SKOR2 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for SKOR2. It may not necessarily be applicable to this product.
 NCBI GI #    83699422
 NCBI GeneID    652991
 NCBI Accession #    NP_001032891.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001037802.1 [Other Products]
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 UniProt Primary Accession #    Q2VWA4 [Other Products]
 UniProt Related Accession #    Q2VWA4 [Other Products]
 Molecular Weight    104235
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 NCBI Official Full Name    SKI family transcriptional corepressor 2 isoform 2
 NCBI Official Synonym Full Names    SKI family transcriptional corepressor 2
 NCBI Official Symbol    SKOR2 [Similar Products]
 NCBI Official Synonym Symbols   
CORL2; CH18515; FUSSEL18
[Similar Products]
 NCBI Protein Information    SKI family transcriptional corepressor 2
 UniProt Protein Name    SKI family transcriptional corepressor 2
 UniProt Synonym Protein Names   
Functional Smad-suppressing element on chromosome 18; Fussel-18; LBX1 corepressor 1-like protein; Ladybird homeobox corepressor 1-like protein
 Protein Family    SKI family transcriptional corepressor
 UniProt Gene Name    SKOR2 [Similar Products]
 UniProt Synonym Gene Names    CORL2; FUSSEL18; Fussel-18 [Similar Products]
 UniProt Entry Name    SKOR2_HUMAN
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 UniProt Comments for SKOR2    FUSSEL18: Exhibits transcriptional repressor activity. Acts as a TGF-beta antagonist in the nervous system. Belongs to the SKI family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription regulation

Chromosomal Location of Human Ortholog: 18q21.1

Cellular Component: cytoplasm; nucleus

Molecular Function: SMAD binding; transcription corepressor activity

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transforming growth factor beta receptor signaling pathway
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Product References and Citations for anti-SKOR2 antibody

   Arndt S.,et al.Lab. Invest. 85:1330-1341(2005).
Nusbaum C.,et al.Nature 437:551-555(2005).
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 Research Articles on SKOR2    1. Experiments performed using mice, but the observations maybe relevant to other organisms as well.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SKOR2 antibodyOrgans/Tissues associated with anti-SKOR2 antibody
 Reference Product  PubMed Publications
 TBX2 antibody  >1 publications with SKOR2 and TBX2
 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >2 publications with SKOR2 and Mixed
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