View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List anti-SLC12A6 antibody :: Rabbit SLC12A6 Polyclonal Antibody Catalog # MBS4156005 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name SLC12A6, Polyclonal Antibody Full Product Name Anti-SLC12A6 Antibody Product Gene Name anti-SLC12A6 antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM 218000 Clonality Polyclonal Isotype IgG Host Rabbit Species Reactivity Human, Mouse, Rat Purity/Purification Affinity Purification Concentration 1mg/ml (lot specific) Immunogen Recombinant protein of human SLC12A6 Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Preparation and Storage Store at -20 degree C. Avoid freeze/thaw cycles. Other Notes Small volumes of anti-SLC12A6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-SLC12A6 antibody This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. Applications Tested/Suitable for anti-SLC12A6 antibody Western Blot (WB) Application Notes for anti-SLC12A6 antibody WB: 1:500-1:2000 TOP NCBI/Uniprot data below describe general gene information for SLC12A6. It may not necessarily be applicable to this product. NCBI GI # 152061007 NCBI GeneID 9990 NCBI Accession # AAI50585.1 [Other Products] UniProt Secondary Accession # Q2VI00; Q7Z2E7; Q7Z4G5; Q8TDD4; Q9UFR2; Q9Y642; Q9Y665; A0AV76[Other Products] UniProt Related Accession # Q9UHW9[Other Products] Molecular Weight 120,467 Da TOP NCBI Official Full Name SLC12A6 protein, partial NCBI Official Synonym Full Names solute carrier family 12 member 6 NCBI Official Symbol SLC12A6 [Similar Products] NCBI Official Synonym Symbols KCC3; ACCPN; KCC3A; KCC3B [Similar Products] NCBI Protein Information solute carrier family 12 member 6 UniProt Protein Name Solute carrier family 12 member 6 UniProt Synonym Protein Names Electroneutral potassium-chloride cotransporter 3; K-Cl cotransporter 3 Protein Family Solute carrier family UniProt Gene Name SLC12A6 [Similar Products] UniProt Synonym Gene Names KCC3 [Similar Products] TOP NCBI Summary for SLC12A6 This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq, Jul 2008] TOP UniProt Comments for SLC12A6 Mediates electroneutral potassium-chloride cotransport. May be activated by cell swelling. May contribute to cell volume homeostasis in single cells. Research Articles on SLC12A6 1. Neurodegenerative deficits in hereditary motor and sensory neuropathy associated with agenesis of the corpus callosum are primarily caused by an axonopathy superimposed upon abnormal development, affecting peripheral but also central nervous system axons, all ultimately because of a genetic defect in the axonal cotransporter KCC3. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-SLC12A6 antibody Reference Product PubMed Publications STK39 antibody >3 publications with SLC12A6 and STK39 SPG11 antibody >2 publications with SLC12A6 and SPG11 ZFYVE26 antibody >1 publications with SLC12A6 and ZFYVE26 Pathways associated with anti-SLC12A6 antibody Products by Pathway Pathway Diagram Cation-coupled Chloride Cotransporters Pathway antibodies Cation-coupled Chloride Cotransporters Pathway Diagram SLC-mediated Transmembrane Transport Pathway antibodies SLC-mediated Transmembrane Transport Pathway Diagram Transmembrane Transport Of Small Molecules Pathway antibodies Transmembrane Transport Of Small Molecules Pathway Diagram Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway antibodies Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway Diagram Diseases associated with anti-SLC12A6 antibody Disease Name Pubmed Publications Peripheral Nervous System Diseases Antibodies >20 publications with SLC12A6 and Peripheral Nervous System Diseases Congenital Abnormalities Antibodies >18 publications with SLC12A6 and Congenital Abnormalities Hypertension Antibodies >5 publications with SLC12A6 and Hypertension Atrophy Antibodies >5 publications with SLC12A6 and Atrophy Corpus callosum agenesis neuronopathy Antibodies >5 publications with SLC12A6 and Corpus callosum agenesis neuronopathy Nerve Degeneration Antibodies >4 publications with SLC12A6 and Nerve Degeneration Cognition Disorders Antibodies >3 publications with SLC12A6 and Cognition Disorders Abnormalities, Multiple Antibodies >2 publications with SLC12A6 and Abnormalities, Multiple Kidney Diseases Antibodies >2 publications with SLC12A6 and Kidney Diseases Adenocarcinoma Antibodies >1 publications with SLC12A6 and Adenocarcinoma Organs/Tissues associated with anti-SLC12A6 antibody Organ/Tissue Name Pubmed Publications Brain Antibodies >26 publications with SLC12A6 and Brain Blood Antibodies >14 publications with SLC12A6 and Blood Muscle Antibodies >10 publications with SLC12A6 and Muscle Kidney Antibodies >9 publications with SLC12A6 and Kidney Heart Antibodies >4 publications with SLC12A6 and Heart Vascular Antibodies >3 publications with SLC12A6 and Vascular Stomach Antibodies >3 publications with SLC12A6 and Stomach Liver Antibodies >2 publications with SLC12A6 and Liver Embryonic Tissue Antibodies >2 publications with SLC12A6 and Embryonic Tissue Lung Antibodies >2 publications with SLC12A6 and Lung TOP © 2006-24 MyBioSource.com. All rights reserved. Privacy Policy | Terms & Conditions Our Best Sellers SLC26A5 Antibody HSD17B1 Antibody N-terminal pro-brain natriuretic peptide (NT-proBNP) ELISA Kit LAT1 Blocking Peptide Lymphocyte Activation Gene 3 (LAG3) Antibody AP-3 complex subunit beta-2 (AP3B2) Recombinant Protein UHRF2 Antibody Actinin-alpha1-2-3-4 Antibody ELISA Antibodies Secondary Antibodies Antigens Biochemicals cDNA Clones Kits Peptides Rec Proteins Protein Family Request a Quote Please fill out the form below and our representative will get back to you shortly. Catalog # MBS000000 Your E-mail (required) Ship to Country (required) United StatesAfghanistanAlbaniaAlgeriaAmerican SamoaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBoliviaBosnia and HerzegowinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCook IslandsCosta RicaCote DIvoireCroatiaCubaCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEast TimorEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrance MetropolitanFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuamGuatemalaGuineaGuinea-bissauGuyanaHaitiHeard and Mc Donald IslandsHondurasHong KongHungaryIcelandIndiaIndonesiaIran (Islamic Republic of)IraqIrelandIsraelItalyJamaicaJapanJordanKazakhstanKenyaKiribatiKorea Democratic People Republic ofKorea Republic ofKuwaitKyrgyzstanLao People Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacauMacedonia The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMarshall IslandsMartiniqueMauritaniaMauritiusMayotteMexicoMicronesia Federated States ofMoldova Republic ofMonacoMongoliaMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNetherlands AntillesNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorthern Mariana IslandsNorwayOmanPakistanPalauPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalPuerto RicoQatarReunionRomaniaRussian FederationRwandaSaint Kitts and NevisSaint LuciaSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSeychellesSierra LeoneSingaporeSlovakia (Slovak Republic)SloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSpainSri LankaSt. HelenaSt. Pierre and MiquelonSudanSurinameSvalbard and Jan Mayen IslandsSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania United Republic ofThailandTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUnited States Minor Outlying IslandsUruguayUzbekistanVanuatuVatican City State (Holy See)VenezuelaViet NamVirgin Islands (British)Virgin Islands (U.S.)Wallis and Futuna IslandsWestern SaharaYemenYugoslaviaZaireZambiaZimbabwe Postal/Zip Code (required) Your Name Your Telephone Your Inquiries, Comments or Full Shipping Address (required) Contact Us Please fill out the form below and our representative will get back to you shortly. Inquiry for # MBS000000 Your Name Your Telephone Your E-mail (required) Your Inquiries or Comments