AFC36890.1
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NCBI Official Full Name
SLC14A1, partial
NCBI Summary for SLC14A1
The protein encoded by this gene is a membrane transporter that mediates urea transport in erythrocytes. This gene forms the basis for the Kidd blood group system. [provided by RefSeq, Mar 2009]
UniProt Comments for SLC14A1
SLC14A1: Specialized low-affinity urea transporter. Mediates urea transport in erythrocytes. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Transporter; Transporter, SLC family; Membrane protein, integral
Chromosomal Location of Human Ortholog: 18q11-q12
Cellular Component: integral to plasma membrane; basolateral plasma membrane; plasma membrane
Molecular Function: urea channel activity; water transporter activity; urea transmembrane transporter activity
Biological Process: water transport; urea transport; transmembrane transport
Disease: Blood Group--kidd System
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