NP_006508.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 60 kD Predicted: 60 kDa
NCBI Official Full Name
monocarboxylate transporter 8
NCBI Official Synonym Full Names
solute carrier family 16 member 2
NCBI Official Synonym Symbols
AHDS; MCT7; MCT8; XPCT; MCT 7; MCT 8; MRX22; DXS128; DXS128E [Similar Products]
NCBI Protein Information
monocarboxylate transporter 8
UniProt Protein Name
Monocarboxylate transporter 8
UniProt Synonym Protein Names
Monocarboxylate transporter 7; MCT 7; Solute carrier family 16 member 2; X-linked PEST-containing transporter
UniProt Synonym Gene Names
NCBI Summary for SLC16A2
This gene encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). This gene is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. This gene is subject to X-chromosome inactivation. Mutations in this gene are the cause of Allan-Herndon-Dudley syndrome. [provided by RefSeq, Mar 2012]
UniProt Comments for SLC16A2
Very active and specific thyroid hormone transporter. Stimulates cellular uptake of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine. Does not transport Leu, Phe, Trp or Tyr.
Research Articles on SLC16A2
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Diseases associated with anti-SLC16A2 antibody
Organs/Tissues associated with anti-SLC16A2 antibody
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