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anti-SLC16A7 antibody :: Rabbit anti-Human, Rat SLC16A7 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7049136
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SLC16A7, Polyclonal Antibody

★Popular Item★
 Also Known As   

SLC16A7 Antibody

 Product Synonym Names    Monocarboxylate transporter 2; MCT 2; Solute carrier family 16 member 7; SLC16A7; MCT2
 Product Gene Name   

anti-SLC16A7 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    AF049608 mRNA
 3D Structure    ModBase 3D Structure for O60669
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Rat
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 Purity/Purification    >95%, Protein G purified
 Form/Format    Liquid
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 Immunogen    Recombinant Human Monocarboxylate transporter 2 protein (197-279AA)
 Preservative    0.03% Proclin 300
 Constituents    50% Glycerol, 0.01M PBS, pH 7.4
 Conjugation    Non-conjugated
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-50322
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-SLC16A7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SLC16A7 antibody

   Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Functions as high-affinity pyruvate transporter.
 Applications Tested/Suitable for anti-SLC16A7 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

 Application Notes for anti-SLC16A7 antibody    WB: 1: 500-1: 5000
IHC: 1: 20-1: 200
IF: 1: 50-1: 200
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 Western Blot (WB) of anti-SLC16A7 antibody    Western Blot
Positive WB detected in: A549 whole cell lysate,HepG2 whole cell lysate,HEK293 whole cell lysate,Rat liver tissue
All lanes: SLC16A7 antibody at 2.5ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 53 KDa
Observed band size: 53 KDa

anti-SLC16A7 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-SLC16A7 antibody    Immunohistochemistry of paraffin-embedded human heart tissue using MBS7049136 at dilution of 1:100
anti-SLC16A7 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-SLC16A7 antibody    Immunohistochemistry of paraffin-embedded human testis tissue using MBS7049136 at dilution of 1:100
anti-SLC16A7 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-SLC16A7 antibody    Immunofluorescent analysis of HepG2 cells using MBS7049136 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-SLC16A7 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for SLC16A7. It may not necessarily be applicable to this product.
 NCBI GI #    397739033
 NCBI GeneID    9194
 NCBI Accession #    NP_001257551.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001270622.1 [Other Products]
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 UniProt Primary Accession #    O60669 [Other Products]
 UniProt Secondary Accession #    Q8NEM3; Q9UPB3 [Other Products]
 UniProt Related Accession #    O60669 [Other Products]
 Molecular Weight    52,200 Da
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 NCBI Official Full Name    monocarboxylate transporter 2
 NCBI Official Synonym Full Names    solute carrier family 16 member 7
 NCBI Official Symbol    SLC16A7 [Similar Products]
 NCBI Official Synonym Symbols   
MCT2
[Similar Products]
 NCBI Protein Information    monocarboxylate transporter 2
 UniProt Protein Name    Monocarboxylate transporter 2
 UniProt Synonym Protein Names   
Solute carrier family 16 member 7
 Protein Family    Monocarboxylate transporter
 UniProt Gene Name    SLC16A7 [Similar Products]
 UniProt Synonym Gene Names    MCT2; MCT 2 [Similar Products]
 UniProt Entry Name    MOT2_HUMAN
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 NCBI Summary for SLC16A7    This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
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 UniProt Comments for SLC16A7    SLC16A7: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a high affinity pyruvate transporter. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: lactate transmembrane transporter activity; monocarboxylic acid transmembrane transporter activity; pyruvate secondary active transmembrane transporter activity; pyruvate transmembrane transporter activity
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 Research Articles on SLC16A7    1. SLC16A7 (MCT2) epigenetic regulation results in protein over-expression, affecting signalling and cellular phenotypes in prostate cancer
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-SLC16A7 antibodyDiseases associated with anti-SLC16A7 antibody
 Products by Pathway  Pathway Diagram
 Proton-coupled Monocarboxylate Transport Pathway antibodies  Proton-coupled Monocarboxylate Transport Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies  Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >15 publications with SLC16A7 and Brain Diseases
 Disease Models, Animal Antibodies  >12 publications with SLC16A7 and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >7 publications with SLC16A7 and Cardiovascular Diseases
 Necrosis Antibodies  >5 publications with SLC16A7 and Necrosis
 Genital Diseases, Male Antibodies  >5 publications with SLC16A7 and Genital Diseases, Male
 Lung Diseases Antibodies  >3 publications with SLC16A7 and Lung Diseases
 Liver Diseases Antibodies  >3 publications with SLC16A7 and Liver Diseases
 Lung Neoplasms Antibodies  >3 publications with SLC16A7 and Lung Neoplasms
 Obesity Antibodies  >3 publications with SLC16A7 and Obesity
 Liver Neoplasms Antibodies  >2 publications with SLC16A7 and Liver Neoplasms
Organs/Tissues associated with anti-SLC16A7 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >61 publications with SLC16A7 and Brain
 Blood Antibodies  >36 publications with SLC16A7 and Blood
 Kidney Antibodies  >10 publications with SLC16A7 and Kidney
 Testis Antibodies  >6 publications with SLC16A7 and Testis
 Connective Tissue Antibodies  >1 publications with SLC16A7 and Connective Tissue
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