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anti-Slc19a1 antibody :: Goat SLC19A1/RFC1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS422803 anti-Slc19a1 antibody
Unit / Price
0.1 mg  /  $225 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SLC19A1/RFC1, Polyclonal Antibody

★Popular Item★
 Also Known As   

Goat anti-SLC19A1/RFC1 (mouse) Antibody

 Product Synonym Names    Slc19a1; solute carrier family 19 (folate transporter), member 1; AI323572; RFC; RFC-1; RFC1; IFC-1; OTTMUSP00000045639; OTTMUSP00000045641; folate transporter 1; intestinal folate carrier 1; intestinal folate carrier protein; reduced folate carrier 1; so; Slc19a1 antibody; solute carrier family 19 (folate transporter); member 1 antibody; AI323572 antibody; RFC antibody; RFC-1 antibody; RFC1 antibody; IFC-1 antibody; OTTMUSP00000045639 antibody; OTTMUSP00000045641 antibody; folate transporter 1 antibody; intestinal folate carrier 1 antibody; intestinal folate carrier protein antibody; reduced folate carrier 1 antibody; solute carrier family 19 member 1 antibody; SLC19A1 / RFC1 (mouse)
 Product Gene Name   

anti-Slc19a1 antibody

[Similar Products]
 Product Synonym Gene Name    RFC1 [Similar Products]
 Antibody/Peptide Pairs    SLC19A1 / RFC1 peptide (MBS427408) is used for blocking the activity of SLC19A1/RFC1 antibody (MBS422803)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    KQAYEEPRQD HELK
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Expected from sequence similarity: Mouse, Rat
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence KQAYEEPRQDHELK-C, from the N Terminus of the protein sequence according to NP_112473.1.
 Epitope    N Terminus
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-Slc19a1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-Slc19a1 antibody   

Peptide ELISA (EIA)

 Application Notes for anti-Slc19a1 antibody    Peptide ELISA: Antibody detection limit dilution 1: 128000.
Western Blot: Preliminary experiments gave bands at approx 65kDa and 26kDa in Mouse Skin lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 58.2kDa according to NP_112473.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).
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NCBI/Uniprot data below describe general gene information for Slc19a1. It may not necessarily be applicable to this product.
 NCBI GI #    13654260
 NCBI GeneID    20509
 NCBI Accession #    NP_112473.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_031196.3 [Other Products]
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 UniProt Secondary Accession #    Q62450; Q62451 [Other Products]
 UniProt Related Accession #    P41438 [Other Products]
 Molecular Weight    43,371 Da
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 NCBI Official Full Name    folate transporter 1
 NCBI Official Synonym Full Names    solute carrier family 19 (folate transporter), member 1
 NCBI Official Symbol    Slc19a1 [Similar Products]
 NCBI Official Synonym Symbols   
RFC; RFC1; RFC-1; AI323572
[Similar Products]
 NCBI Protein Information    folate transporter 1
 UniProt Protein Name    Folate transporter 1
 UniProt Synonym Protein Names   
Intestinal folate carrier 1; IFC-1; Reduced folate carrier 1; RFC-1; RFC1; Solute carrier family 19 member 1
 UniProt Gene Name    Slc19a1 [Similar Products]
 UniProt Synonym Gene Names    IFC-1; RFC-1; RFC1 [Similar Products]
 UniProt Entry Name    S19A1_MOUSE
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 UniProt Comments for Slc19a1    SLC19A1: a transporter protein. Transports reduced folate, antitumor agents and folate antagonists such as methotrexate. Apparently involved in methotrexate resistance in various cancers and neural tube defects.

Protein type: Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-pass; Transporter

Cellular Component: apical plasma membrane; basolateral plasma membrane; brush border membrane; integral to membrane; integral to plasma membrane; membrane; plasma membrane

Molecular Function: folic acid binding; folic acid transporter activity; methotrexate transporter activity; reduced folate carrier activity

Biological Process: folic acid transport; methotrexate transport; transmembrane transport; transport
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 Research Articles on Slc19a1    1. The mRNAs encoding Folr2 and the intestinal folate transporter Slc46a1 were not detected in 2-cel embryos and blastocysts.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Slc19a1 antibodyPathways associated with anti-Slc19a1 antibody
 Reference Product  PubMed Publications
 Mtr antibody  >42 publications with Slc19a1 and Mtr
 Mtrr antibody  >32 publications with Slc19a1 and Mtrr
 Slc46a1 antibody  >25 publications with Slc19a1 and Slc46a1
 Ggh antibody  >23 publications with Slc19a1 and Ggh
 Fpgs antibody  >23 publications with Slc19a1 and Fpgs
 Folr1 antibody  >21 publications with Slc19a1 and Folr1
 Tcn2 antibody  >12 publications with Slc19a1 and Tcn2
 Folr2 antibody  >10 publications with Slc19a1 and Folr2
 Ubc antibody  >1 publications with Slc19a1 and Ubc
 Products by Pathway  Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Folate And Pterines Pathway antibodies  Metabolism Of Folate And Pterines Pathway Diagram
 Metabolism Of Vitamins And Cofactors Pathway antibodies  Metabolism Of Vitamins And Cofactors Pathway Diagram
 Metabolism Of Water-soluble Vitamins And Cofactors Pathway antibodies  Metabolism Of Water-soluble Vitamins And Cofactors Pathway Diagram
 Vitamin Digestion And Absorption Pathway antibodies  Vitamin Digestion And Absorption Pathway Diagram
 Vitamin Digestion And Absorption Pathway antibodies  Vitamin Digestion And Absorption Pathway Diagram
Diseases associated with anti-Slc19a1 antibodyOrgans/Tissues associated with anti-Slc19a1 antibody
 Disease Name  Pubmed Publications
 Neoplasms, Experimental Antibodies  >64 publications with Slc19a1 and Neoplasms, Experimental
 Nervous System Diseases Antibodies  >62 publications with Slc19a1 and Nervous System Diseases
 Congenital Abnormalities Antibodies  >58 publications with Slc19a1 and Congenital Abnormalities
 Precursor Cell Lymphoblastic Leukemia-Lymphoma Antibodies  >42 publications with Slc19a1 and Precursor Cell Lymphoblastic Leukemia-Lymphoma
 Neural Tube Defects Antibodies  >38 publications with Slc19a1 and Neural Tube Defects
 Cardiovascular Diseases Antibodies  >32 publications with Slc19a1 and Cardiovascular Diseases
 Lung Neoplasms Antibodies  >28 publications with Slc19a1 and Lung Neoplasms
 Breast Neoplasms Antibodies  >24 publications with Slc19a1 and Breast Neoplasms
 Colorectal Neoplasms Antibodies  >22 publications with Slc19a1 and Colorectal Neoplasms
 Disease Models, Animal Antibodies  >19 publications with Slc19a1 and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >156 publications with Slc19a1 and Blood
 Intestine Antibodies  >52 publications with Slc19a1 and Intestine
 Kidney Antibodies  >42 publications with Slc19a1 and Kidney
 Lung Antibodies  >36 publications with Slc19a1 and Lung
 Brain Antibodies  >30 publications with Slc19a1 and Brain
 Ovary Antibodies  >23 publications with Slc19a1 and Ovary
 Heart Antibodies  >18 publications with Slc19a1 and Heart
 Bone Antibodies  >17 publications with Slc19a1 and Bone
 Embryonic Tissue Antibodies  >15 publications with Slc19a1 and Embryonic Tissue
 Bone Marrow Antibodies  >11 publications with Slc19a1 and Bone Marrow
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