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anti-SLC25A4 antibody :: Rabbit anti-Human, mouse SLC25A4 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7006610
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SLC25A4, Polyclonal Antibody

★Popular Item★
 Also Known As   

SLC25A4 Antibody

 Product Synonym Names    ADP/ATP translocase 1; SLC25A4; ANT1; ADP; ATP carrier protein 1; ADP; ATP carrier protein; heart/skeletal muscle isoform T1; Adenine nucleotide translocator 1; ANT 1; Solute carrier family 25 member 4
 Product Gene Name   

anti-SLC25A4 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    103220
 3D Structure    ModBase 3D Structure for P12235
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, mouse
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 Purity/Purification    Affinity Purified
 Form/Format    Liquid
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 Immunogen    Recombinant human ADP/ATP translocase 1 protein
 Conjugation    Non-conjugated
 Storage Buffer    Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-9299 / sc-9300 / sc-11433
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-SLC25A4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SLC25A4 antibody

   Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane.
 Applications Tested/Suitable for anti-SLC25A4 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-SLC25A4 antibody    Recommended dilution: WB:1:500-2000, IHC:1:20-1:200
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 Immunohistochemistry (IHC) of anti-SLC25A4 antibody    Immunohistochemistry of paraffin-embedded human small intestine tissue using MBS7006610 at dilution of 1:100
anti-SLC25A4 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-SLC25A4 antibody    Immunohistochemistry of paraffin-embedded human breast cancer using MBS7006610 at dilution of 1:100
anti-SLC25A4 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-SLC25A4 antibody    Immunofluorescence staining of PC3 cells with MBS7006610 at 1:266,counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 degree C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
anti-SLC25A4 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for SLC25A4. It may not necessarily be applicable to this product.
 NCBI GI #    55749577
 NCBI GeneID    291
 NCBI Accession #    NP_001142.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001151.3 [Other Products]
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 UniProt Primary Accession #    P12235 [Other Products]
 UniProt Secondary Accession #    D3DP59 [Other Products]
 UniProt Related Accession #    P12235 [Other Products]
 Molecular Weight    33,064 Da
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 NCBI Official Full Name    ADP/ATP translocase 1
 NCBI Official Synonym Full Names    solute carrier family 25 member 4
 NCBI Official Symbol    SLC25A4 [Similar Products]
 NCBI Official Synonym Symbols   
T1; ANT; AAC1; ANT1; PEO2; PEO3; ANT 1; PEOA2; MTDPS12
[Similar Products]
 NCBI Protein Information    ADP/ATP translocase 1
 UniProt Protein Name    ADP/ATP translocase 1
 UniProt Synonym Protein Names   
ADP,ATP carrier protein 1; ADP,ATP carrier protein, heart/skeletal muscle isoform T1; Adenine nucleotide translocator 1; ANT 1; Solute carrier family 25 member 4
 Protein Family    ADP/ATP translocase
 UniProt Gene Name    SLC25A4 [Similar Products]
 UniProt Synonym Gene Names    ANT1; ANT 1 [Similar Products]
 UniProt Entry Name    ADT1_HUMAN
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 NCBI Summary for SLC25A4    This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Mutations in this gene have been shown to result in autosomal dominant progressive external opthalmoplegia and familial hypertrophic cardiomyopathy. [provided by RefSeq, Jun 2013]
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 UniProt Comments for SLC25A4    SLC25A4: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. Defects in SLC25A4 are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions autosomal dominant type 2 (PEOA2). Progressive external ophthalmoplegia is characterized by progressive weakness of ocular muscles and levator muscle of the upper eyelid. In a minority of cases, it is associated with skeletal myopathy, which predominantly involves axial or proximal muscles and which causes abnormal fatigability and even permanent muscle weakness. Ragged- red fibers and atrophy are found on muscle biopsy. A large proportion of chronic ophthalmoplegias are associated with other symptoms, leading to a multisystemic pattern of this disease. Additional symptoms are variable, and may include cataracts, hearing loss, sensory axonal neuropathy, ataxia, depression, hypogonadism, and parkinsonism. Belongs to the mitochondrial carrier family.

Protein type: Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-pass; Mitochondrial; Transporter

Chromosomal Location of Human Ortholog: 4q35

Cellular Component: integral to plasma membrane; mitochondrial inner membrane; mitochondrion; myelin sheath; nucleus

Molecular Function: adenine transmembrane transporter activity; protein binding; structural constituent of ribosome

Biological Process: adenine transport; apoptotic mitochondrial changes; energy reserve metabolic process; generation of precursor metabolites and energy; mitochondrial genome maintenance; regulation of insulin secretion; translation; transmembrane transport; transport; viral reproduction

Disease: Mitochondrial Dna Depletion Syndrome 12 (cardiomyopathic Type); Progressive External Ophthalmoplegia With Mitochondrial Dna Deletions, Autosomal Dominant, 2
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 Research Articles on SLC25A4    1. Identification of ZNF555 as a putative transcriptional factor that impacts ANT1 promoter activity in facioscapulohumeral dystrophy myoblasts.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SLC25A4 antibodyPathways associated with anti-SLC25A4 antibody
 Reference Product  PubMed Publications
 POLG antibody  >4 publications with SLC25A4 and POLG
 VDAC1 antibody  >1 publications with SLC25A4 and VDAC1
 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Electron Transport Chain Pathway antibodies  Electron Transport Chain Pathway Diagram
 HIV Infection Pathway antibodies  HIV Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Host Interactions Of HIV Factors Pathway antibodies  Host Interactions Of HIV Factors Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
Diseases associated with anti-SLC25A4 antibodyOrgans/Tissues associated with anti-SLC25A4 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >7 publications with SLC25A4 and Nervous System Diseases
 Brain Diseases Antibodies  >2 publications with SLC25A4 and Brain Diseases
 Heart Diseases Antibodies  >2 publications with SLC25A4 and Heart Diseases
 Cardiovascular Diseases Antibodies  >2 publications with SLC25A4 and Cardiovascular Diseases
 Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 1 Antibodies  >2 publications with SLC25A4 and Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant, 1
 Anemia Antibodies  >1 publications with SLC25A4 and Anemia
 Infertility, Male Antibodies  >1 publications with SLC25A4 and Infertility, Male
 Hypertrophy Antibodies  >1 publications with SLC25A4 and Hypertrophy
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with SLC25A4 and Prenatal Exposure Delayed Effects
 Fibrosis Antibodies  >1 publications with SLC25A4 and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >17 publications with SLC25A4 and Muscle
 Heart Antibodies  >5 publications with SLC25A4 and Heart
 Embryonic Tissue Antibodies  >3 publications with SLC25A4 and Embryonic Tissue
 Brain Antibodies  >3 publications with SLC25A4 and Brain
 Skin Antibodies  >2 publications with SLC25A4 and Skin
 Blood Antibodies  >2 publications with SLC25A4 and Blood
 Stomach Antibodies  >1 publications with SLC25A4 and Stomach
 Nerve Antibodies  >1 publications with SLC25A4 and Nerve
 Kidney Antibodies  >1 publications with SLC25A4 and Kidney
 Prostate Antibodies  >1 publications with SLC25A4 and Prostate
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