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anti-SLC25A5 antibody :: Rabbit SLC25A5 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9609496
Unit / Price
0.1 mL  /  $255 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SLC25A5, Polyclonal Antibody

★Popular Item★
 Also Known As   

SLC25A5 Antibody

 Product Synonym Names    2F1; AAC2; Adenine nucleotide translocator 2; ADP; ADP ATP carrier protein 2; ADP/ATP translocase 2; ADT2_HUMAN; ANT 2; ANT2; ATP carrier protein 2; ATP carrier protein; fibroblast isoform; OTTHUMP00000024324; SLC25A5; Solute carrier family 25 (mitochondrial carrier adenine nucleotide translocator) member 5; Solute carrier family 25 member 5; T2; T3
 Product Gene Name   

anti-SLC25A5 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P05141
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    SLC25A5 antibody detects endogenous levels of total SLC25A5
 Purity/Purification    The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
 Form/Format    Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
 Concentration    1mg/ml (lot specific)
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 Immunogen    A synthesized peptide derived from human SLC25A5
 Subcellular Location    Mitochondrion Inner Membrane.
 Conjugation    Unconjugated
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 Preparation and Storage    Store at -20 degree C. Stable for 12 months from date of receipt.
 Other Notes    Small volumes of anti-SLC25A5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SLC25A5 antibody

   Function: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.
Subunit Structure: Homodimer. Component of the MMXD complex, which includes CIAO1, ERCC2, FAM96B, MMS19 and SLC25A5. Interacts with HIV-1 Vpr.
Similarity: The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. Odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue. Belongs to the mitochondrial carrier (TC 2.A.29) family.
 Applications Tested/Suitable for anti-SLC25A5 antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-SLC25A5 antibody    WB: 1:1000-3000
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 Western Blot (WB) of anti-SLC25A5 antibody    Western blot analysis of extracts from mouse brain, using SLC25A5 Antibody. Lane 1 was treated with the blocking peptide.
anti-SLC25A5 antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-SLC25A5 antibody    Western blot analysis SLC25A5 using COLO205 whole cell lysates
anti-SLC25A5 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for SLC25A5. It may not necessarily be applicable to this product.
 NCBI GI #    156071459
 NCBI GeneID    292
 NCBI Accession #    NP_001143.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001152.4 [Other Products]
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 UniProt Primary Accession #    P05141 [Other Products]
 UniProt Secondary Accession #    O43350; B2RCV1 [Other Products]
 UniProt Related Accession #    P05141 [Other Products]
 Molecular Weight    Observed: 33 kDa
Predicted: 33 kDa
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 NCBI Official Full Name    ADP/ATP translocase 2
 NCBI Official Synonym Full Names    solute carrier family 25 member 5
 NCBI Official Symbol    SLC25A5 [Similar Products]
 NCBI Official Synonym Symbols   
T2; T3; 2F1; AAC2; ANT2
[Similar Products]
 NCBI Protein Information    ADP/ATP translocase 2
 UniProt Protein Name    ADP/ATP translocase 2
 UniProt Synonym Protein Names   
ADP,ATP carrier protein 2; ADP,ATP carrier protein, fibroblast isoform; Adenine nucleotide translocator 2; ANT 2
 Protein Family    ADP/ATP translocase
 UniProt Gene Name    SLC25A5 [Similar Products]
 UniProt Synonym Gene Names    ANT2; ANT 2 [Similar Products]
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 NCBI Summary for SLC25A5    This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013]
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 UniProt Comments for SLC25A5    Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.
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 Research Articles on SLC25A5    1. Findings suggest that ANT2 overexpression contributes to EGFR-TKI resistance in non-small cell lung cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SLC25A5 antibodyPathways associated with anti-SLC25A5 antibody
 Reference Product  PubMed Publications
 VDAC3 antibody  >1 publications with SLC25A5 and VDAC3
 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Electron Transport Chain Pathway antibodies  Electron Transport Chain Pathway Diagram
 HIV Infection Pathway antibodies  HIV Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Host Interactions Of HIV Factors Pathway antibodies  Host Interactions Of HIV Factors Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
Diseases associated with anti-SLC25A5 antibodyOrgans/Tissues associated with anti-SLC25A5 antibody
 Disease Name  Pubmed Publications
 Neurobehavioral Manifestations Antibodies  >3 publications with SLC25A5 and Neurobehavioral Manifestations
 Anemia Antibodies  >1 publications with SLC25A5 and Anemia
 Liver Diseases Antibodies  >1 publications with SLC25A5 and Liver Diseases
 Hepatomegaly Antibodies  >1 publications with SLC25A5 and Hepatomegaly
 Carcinoma, Hepatocellular Antibodies  >1 publications with SLC25A5 and Carcinoma, Hepatocellular
 Infertility, Male Antibodies  >1 publications with SLC25A5 and Infertility, Male
 Liver Neoplasms Antibodies  >1 publications with SLC25A5 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >3 publications with SLC25A5 and Liver
 Skin Antibodies  >3 publications with SLC25A5 and Skin
 Brain Antibodies  >3 publications with SLC25A5 and Brain
 Embryonic Tissue Antibodies  >2 publications with SLC25A5 and Embryonic Tissue
 Heart Antibodies  >2 publications with SLC25A5 and Heart
 Ovary Antibodies  >1 publications with SLC25A5 and Ovary
 Testis Antibodies  >1 publications with SLC25A5 and Testis
 Stomach Antibodies  >1 publications with SLC25A5 and Stomach
 Eye Antibodies  >1 publications with SLC25A5 and Eye
 Kidney Antibodies  >1 publications with SLC25A5 and Kidney
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