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anti-SLC30A10 antibody :: Rabbit anti-Human, Mouse SLC30A10 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7044073
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SLC30A10, Polyclonal Antibody

★Popular Item★
 Also Known As   

SLC30A10 Antibody

 Product Synonym Names    Zinc transporter 10ZnT-10; Solute carrier family 30 member 10; SLC30A10; ZNT10; ZNT8
 Product Gene Name   

anti-SLC30A10 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    611146
 3D Structure    ModBase 3D Structure for Q6XR72
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    >95%, Protein G purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human Zinc transporter 10 protein
 Conjugate    Non-conjugated
 Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-160941 / sc-160942
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-SLC30A10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SLC30A10 antibody

   Plays a pivotal role in manganese transport. Manganese is an essential cation for the function of several enzymes, including some crucially important for the metabolism of neurotransmitters and other neuronal metabolic pathways.
 Applications Tested/Suitable for anti-SLC30A10 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

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 Western Blot (WB) of anti-SLC30A10 antibody    Western Blot
Positive WB detected in: Mouse brain tissue
All lanes: SLC30A10 antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 53,27,25 KDa
Observed band size: 53 KDa

anti-SLC30A10 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-SLC30A10 antibody    Immunohistochemistry of paraffin-embedded human spleen tissue using MBS7044073 at dilution of 1:100
anti-SLC30A10 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-SLC30A10 antibody    Immunofluorescent analysis of HepG-2 cells using MBS7044073 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-SLC30A10 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for SLC30A10. It may not necessarily be applicable to this product.
 NCBI GI #    52351208
 NCBI GeneID    55532
 NCBI Accession #    NP_061183.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_018713.2 [Other Products]
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 UniProt Primary Accession #    Q6XR72 [Other Products]
 UniProt Secondary Accession #    Q49AL9; Q9NPW0 [Other Products]
 UniProt Related Accession #    Q6XR72 [Other Products]
 Molecular Weight    24,009 Da
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 NCBI Official Full Name    zinc transporter 10
 NCBI Official Synonym Full Names    solute carrier family 30 member 10
 NCBI Official Symbol    SLC30A10 [Similar Products]
 NCBI Official Synonym Symbols   
ZNT8; ZRC1; HMDPC; ZNT10; ZnT-10; HMNDYT1
[Similar Products]
 NCBI Protein Information    zinc transporter 10
 UniProt Protein Name    Zinc transporter 10
 UniProt Synonym Protein Names   
Solute carrier family 30 member 10
 Protein Family    Zinc transporter
 UniProt Gene Name    SLC30A10 [Similar Products]
 UniProt Synonym Gene Names    ZNT10; ZNT8; ZnT-10 [Similar Products]
 UniProt Entry Name    ZNT10_HUMAN
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 NCBI Summary for SLC30A10    This gene is highly expressed in the liver and is inducible by manganese. Its protein product appears to be critical in maintaining manganese levels, and has higher specificity for manganese than zinc. Loss of function mutations appear to result in a pleomorphic phenotype, including dystonia and adult-onset parkinsonism. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012]
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 UniProt Comments for SLC30A10    SLC30A10: May be involved in zinc transport out of the cell, being a zinc-efflux transporter. Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q41

Cellular Component: plasma membrane

Molecular Function: zinc ion transmembrane transporter activity

Biological Process: manganese ion transport; response to zinc ion

Disease: Hypermanganesemia With Dystonia, Polycythemia, And Cirrhosis
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 Research Articles on SLC30A10    1. We describe early disease manifestations (including videos) in 5 previously unreported Indian children, carrying novel homozygous SLC30A10 mutation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-SLC30A10 antibodyOrgans/Tissues associated with anti-SLC30A10 antibody
 Disease Name  Pubmed Publications
 Dystonia Antibodies  >11 publications with SLC30A10 and Dystonia
 Parkinsonian Disorders Antibodies  >7 publications with SLC30A10 and Parkinsonian Disorders
 Liver Diseases Antibodies  >5 publications with SLC30A10 and Liver Diseases
 Parkinson Disease Antibodies  >5 publications with SLC30A10 and Parkinson Disease
 Liver Cirrhosis Antibodies  >5 publications with SLC30A10 and Liver Cirrhosis
 Hypermanganesemia with Dystonia Polycythemia and Cirrhosis Antibodies  >4 publications with SLC30A10 and Hypermanganesemia with Dystonia Polycythemia and Cirrhosis
 Neurotoxicity Syndromes Antibodies  >4 publications with SLC30A10 and Neurotoxicity Syndromes
 Neoplasms, Experimental Antibodies  >1 publications with SLC30A10 and Neoplasms, Experimental
 Inflammation Antibodies  >1 publications with SLC30A10 and Inflammation
 Fibrosis Antibodies  >1 publications with SLC30A10 and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >17 publications with SLC30A10 and Brain
 Liver Antibodies  >10 publications with SLC30A10 and Liver
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