NP_443176.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
57,098 Da
NCBI Official Full Name
sodium/myo-inositol cotransporter 2 isoform 1
NCBI Official Synonym Full Names
solute carrier family 5 (sodium/inositol cotransporter), member 11
NCBI Protein Information
sodium/myo-inositol cotransporter 2; SLC5A11; homolog of rabbit KST1; sodium/glucose cotransporter KST1; sodium/myo-inositol transporter 2; Na(+)/myo-inositol cotransporter 2; sodium-dependent glucose cotransporter; putative sodium-coupled cotransporter RKST1; solute carrier family 5 (sodium/glucose cotransporter), member 11
UniProt Protein Name
Sodium/myo-inositol cotransporter 2
UniProt Synonym Protein Names
Sodium-dependent glucose cotransporter; Sodium/glucose cotransporter KST1; Sodium/myo-inositol transporter 2; SMIT2; Solute carrier family 5 member 11
UniProt Synonym Gene Names
UniProt Entry Name
SC5AB_HUMAN
NCBI Summary for SLC5A11
Cotransporters, such as SLC5A11, represent a major class of proteins that make use of ion gradients to drive active transport for the cellular accumulation of nutrients, neurotransmitters, osmolytes, and ions Roll et al. (2002) [PubMed 12039040].[supplied by OMIM, Mar 2008]
UniProt Comments for SLC5A11
SLC5A11: Involved in the sodium-dependent cotransport of myo- inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D- xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Transporter; Membrane protein, multi-pass; Transporter, SLC family
Chromosomal Location of Human Ortholog: 16p12.1
Cellular Component: plasma membrane; integral to membrane
Molecular Function: symporter activity
Biological Process: apoptosis; sodium ion transport; carbohydrate transport; transmembrane transport
Research Articles on SLC5A11
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Products associated with anti-SLC5A11 antibody
Pathways associated with anti-SLC5A11 antibody
Diseases associated with anti-SLC5A11 antibody
Organs/Tissues associated with anti-SLC5A11 antibody
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