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anti-SLC6A12 antibody :: Rabbit anti-Human SLC6A12 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7046142
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SLC6A12, Polyclonal Antibody

★Popular Item★
 Also Known As   

SLC6A12 Antibody

 Product Synonym Names    Sodium- and chloride-dependent betaine transporter; BGT-1; Na(+)/Cl(-) betaine/GABA transporter; Solute carrier family 6 member 12; SLC6A12
 Product Gene Name   

anti-SLC6A12 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    603080
 3D Structure    ModBase 3D Structure for P48065
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human Sodium- and chloride-dependent betaine transporter protein (C-100AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-241909
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-SLC6A12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SLC6A12 antibody

   Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.
 Applications Tested/Suitable for anti-SLC6A12 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-SLC6A12 antibody    Western blot
All lanes: SLC6A12 antibody at 4.47 ug/ml
Lane 1: 293T whole cell lysate
Lane 2: PC-3 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 69 kDa
Observed band size: 69 kDa

anti-SLC6A12 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-SLC6A12 antibody    Immunohistochemistry of paraffin-embedded human liver tissue using MBS7046142 at dilution of 1:100
anti-SLC6A12 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for SLC6A12. It may not necessarily be applicable to this product.
 NCBI GI #    171184406
 NCBI GeneID    6539
 NCBI Accession #    NP_001116319.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001122847.2 [Other Products]
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 UniProt Primary Accession #    P48065 [Other Products]
 UniProt Secondary Accession #    A0AV52; B2R992; D3DUN8 [Other Products]
 UniProt Related Accession #    P48065 [Other Products]
 Molecular Weight    69,368 Da
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 NCBI Official Full Name    sodium- and chloride-dependent betaine transporter
 NCBI Official Synonym Full Names    solute carrier family 6 member 12
 NCBI Official Symbol    SLC6A12 [Similar Products]
 NCBI Official Synonym Symbols   
BGT1; GAT2; BGT-1
[Similar Products]
 NCBI Protein Information    sodium- and chloride-dependent betaine transporter
 UniProt Protein Name    Sodium- and chloride-dependent betaine transporter
 UniProt Synonym Protein Names   
BGT-1; Na(+)/Cl(-) betaine/GABA transporter; Solute carrier family 6 member 12
 UniProt Gene Name    SLC6A12 [Similar Products]
 UniProt Entry Name    S6A12_HUMAN
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 UniProt Comments for SLC6A12    SLC6A12: Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily.

Protein type: Membrane protein, integral; Transporter; Membrane protein, multi-pass; Transporter, SLC family

Chromosomal Location of Human Ortholog: 12p13

Cellular Component: integral to membrane; integral to plasma membrane; neuron projection; plasma membrane

Molecular Function: amino acid transmembrane transporter activity; gamma-aminobutyric acid:sodium symporter activity; protein binding

Biological Process: amino acid transport; gamma-aminobutyric acid transport; neurotransmitter transport; synaptic transmission; transport
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 Research Articles on SLC6A12    1. T40 may be important for the trafficking and insertion of BGT1 in the plasma membrane
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SLC6A12 antibodyPathways associated with anti-SLC6A12 antibody
 Reference Product  PubMed Publications
 SLC5A3 antibody  >3 publications with SLC6A12 and SLC5A3
 SLC1A1 antibody  >2 publications with SLC6A12 and SLC1A1
 NFAT5 antibody  >2 publications with SLC6A12 and NFAT5
 SLC1A3 antibody  >1 publications with SLC6A12 and SLC1A3
 Products by Pathway  Pathway Diagram
 Amino Acid Transport Across The Plasma Membrane Pathway antibodies  Amino Acid Transport Across The Plasma Membrane Pathway Diagram
 Creatine Metabolism Pathway antibodies  Creatine Metabolism Pathway Diagram
 GABA Synthesis, Release, Reuptake And Degradation Pathway antibodies  GABA Synthesis, Release, Reuptake And Degradation Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Metabolism Of Polyamines Pathway antibodies  Metabolism Of Polyamines Pathway Diagram
 Na+/Cl- Dependent Neurotransmitter Transporters Pathway antibodies  Na+/Cl- Dependent Neurotransmitter Transporters Pathway Diagram
 Neuronal System Pathway antibodies  Neuronal System Pathway Diagram
 Neurotransmitter Release Cycle Pathway antibodies  Neurotransmitter Release Cycle Pathway Diagram
 Reuptake Of GABA Pathway antibodies  Reuptake Of GABA Pathway Diagram
Diseases associated with anti-SLC6A12 antibodyOrgans/Tissues associated with anti-SLC6A12 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >8 publications with SLC6A12 and Nervous System Diseases
 Seizures Antibodies  >5 publications with SLC6A12 and Seizures
 Disease Models, Animal Antibodies  >3 publications with SLC6A12 and Disease Models, Animal
 Neurobehavioral Manifestations Antibodies  >2 publications with SLC6A12 and Neurobehavioral Manifestations
 Cell Transformation, Neoplastic Antibodies  >1 publications with SLC6A12 and Cell Transformation, Neoplastic
 Drug-Related Side Effects and Adverse Reactions Antibodies  >1 publications with SLC6A12 and Drug-Related Side Effects and Adverse Reactions
 Learning Disorders Antibodies  >1 publications with SLC6A12 and Learning Disorders
 Liver Diseases Antibodies  >1 publications with SLC6A12 and Liver Diseases
 Heart Diseases Antibodies  >1 publications with SLC6A12 and Heart Diseases
 Kidney Diseases Antibodies  >1 publications with SLC6A12 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >17 publications with SLC6A12 and Brain
 Kidney Antibodies  >15 publications with SLC6A12 and Kidney
 Liver Antibodies  >8 publications with SLC6A12 and Liver
 Eye Antibodies  >2 publications with SLC6A12 and Eye
 Intestine Antibodies  >1 publications with SLC6A12 and Intestine
 Lung Antibodies  >1 publications with SLC6A12 and Lung
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