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anti-SLC6A20 antibody :: Rabbit SLC6A20 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9610242
Unit / Price
0.1 mL  /  $255 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SLC6A20, Polyclonal Antibody

★Popular Item★
 Also Known As   

SLC6A20 Antibody

 Product Gene Name   

anti-SLC6A20 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q9NP91
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    SLC6A20 antibody detects endogenous levels of total SLC6A20
 Purity/Purification    The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
 Form/Format    Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
 Concentration    1mg/ml (lot specific)
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 Immunogen    A synthesized peptide derived from human SLC6A20
 Subcellular Location    Plasma Membrane
 Tissue Specificity    Kidney and small intestine. Expressed in the S3 segment of the proximal tubule.
 Conjugation    Unconjugated
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 Preparation and Storage    Store at -20 degree C. Stable for 12 months from date of receipt.
 Other Notes    Small volumes of anti-SLC6A20 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SLC6A20 antibody

   Function: Mediates the calcium-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N-methylated amino acids. Involved in the transport of glycine.
Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A20 subfamily.
 Applications Tested/Suitable for anti-SLC6A20 antibody   

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

 Application Notes for anti-SLC6A20 antibody    WB: 1:1000-3000
IHC: 1:200
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 Western Blot (WB) of anti-SLC6A20 antibody    Western blot analysis SLC6A20 using K562 whole cell lysates
anti-SLC6A20 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-SLC6A20 antibody    MBS9610242 at 1/100 staining Human liver cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
anti-SLC6A20 antibody Immunohistochemistry (IHC) (IHC) image
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 Western Blot (WB) of anti-SLC6A20 antibody    Western blot analysis of extracts from rat liver, using SLC6A20 Antibody.
anti-SLC6A20 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for SLC6A20. It may not necessarily be applicable to this product.
 NCBI GI #    11181770
 NCBI GeneID    54716
 NCBI Accession #    NP_064593.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_020208.3 [Other Products]
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 UniProt Primary Accession #    Q9NP91 [Other Products]
 UniProt Secondary Accession #    O75590; Q8TF10; Q9NPQ2; Q9NQ77; A1A4F2 [Other Products]
 UniProt Related Accession #    Q9NP91 [Other Products]
 Molecular Weight    Observed: 66 kDa
Predicted: 66 kDa
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 NCBI Official Full Name    sodium- and chloride-dependent transporter XTRP3 isoform 1
 NCBI Official Synonym Full Names    solute carrier family 6 member 20
 NCBI Official Symbol    SLC6A20 [Similar Products]
 NCBI Official Synonym Symbols   
XT3; SIT1; Xtrp3
[Similar Products]
 NCBI Protein Information    sodium- and chloride-dependent transporter XTRP3
 UniProt Protein Name    Sodium- and chloride-dependent transporter XTRP3
 UniProt Synonym Protein Names   
Sodium/imino-acid transporter 1; Solute carrier family 6 member 20; Transporter rB21A homolog
 Protein Family    Sodium- and chloride-dependent transporter
 UniProt Gene Name    SLC6A20 [Similar Products]
 UniProt Synonym Gene Names    SIT1; XT3; XTRP3 [Similar Products]
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 NCBI Summary for SLC6A20    Transport of small hydrophilic substances across cell membranes is mediated by substrate-specific transporter proteins which have been classified into several families of related genes. The protein encoded by this gene is a member of the subgroup of transporter with unidentified substrates within the Na+ and Cl- coupled transporter family. This gene is expressed in kidney, and its alternative splicing generates 2 transcript variants. [provided by RefSeq, Jul 2008]
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 UniProt Comments for SLC6A20    Mediates the calcium-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N-methylated amino acids. Involved in the transport of glycine.
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 Research Articles on SLC6A20    1. Imputed meta-analysis revealed that 13 SLC6A20 SNPs were significantly associated with Hirschsprung disease. In further subgroup analysis, SLC6A20 polymorphisms appeared to have increased associations with Long-Segment Hirschsprung disease.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-SLC6A20 antibodyDiseases associated with anti-SLC6A20 antibody
 Products by Pathway  Pathway Diagram
 Amino Acid Transport Across The Plasma Membrane Pathway antibodies  Amino Acid Transport Across The Plasma Membrane Pathway Diagram
 Na+/Cl- Dependent Neurotransmitter Transporters Pathway antibodies  Na+/Cl- Dependent Neurotransmitter Transporters Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies  Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram
 Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway antibodies  Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway Diagram
 Disease Name  Pubmed Publications
 Iminoglycinuria Antibodies  >4 publications with SLC6A20 and Iminoglycinuria
 Myocardial Ischemia Antibodies  >1 publications with SLC6A20 and Myocardial Ischemia
 Adenoma Antibodies  >1 publications with SLC6A20 and Adenoma
 Urination Disorders Antibodies  >1 publications with SLC6A20 and Urination Disorders
 Drug Toxicity Antibodies  >1 publications with SLC6A20 and Drug Toxicity
 Kidney Diseases Antibodies  >1 publications with SLC6A20 and Kidney Diseases
 Neoplasms Antibodies  >1 publications with SLC6A20 and Neoplasms
 Mesothelioma Antibodies  >1 publications with SLC6A20 and Mesothelioma
 HYPERGLYCINURIA Antibodies  >1 publications with SLC6A20 and HYPERGLYCINURIA
Organs/Tissues associated with anti-SLC6A20 antibody
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >10 publications with SLC6A20 and Intestine
 Brain Antibodies  >6 publications with SLC6A20 and Brain
 Nerve Antibodies  >3 publications with SLC6A20 and Nerve
 Lung Antibodies  >2 publications with SLC6A20 and Lung
 Stomach Antibodies  >1 publications with SLC6A20 and Stomach
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