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anti-SLC6A6 antibody :: Rabbit anti-Human SLC6A6 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7001227
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SLC6A6, Polyclonal Antibody

★Popular Item★
 Also Known As   

SLC6A6 Antibody

 Product Synonym Names    Sodium- and chloride-dependent taurine transporter; Solute carrier family 6 member 6; SLC6A6
 Product Gene Name   

anti-SLC6A6 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    186854
 3D Structure    ModBase 3D Structure for P31641
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    >95%,Protein G purified
 Form/Format    Liquid
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 Immunogen    Recombinant human Sodium- and chloride-dependent taurine transporter protein
 Conjugation    Non-conjugated
 Storage Buffer    Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-47453 / sc-47451 / sc-47450 / sc-135257
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-SLC6A6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SLC6A6 antibody

   Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake.
 Applications Tested/Suitable for anti-SLC6A6 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

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 Western Blot (WB) of anti-SLC6A6 antibody    Western blot
All lanes: SLC6A6 antibody at 0.5ug/ml
Lane 1: Human placenta tissue
Lane 2: Hela whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 70,23 kDa
Observed band size: 70 kDa

anti-SLC6A6 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-SLC6A6 antibody    Immunohistochemistry of paraffin-embedded human brain tissue using MBS7001227 at dilution of 1:100
anti-SLC6A6 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-SLC6A6 antibody    Immunohistochemistry of paraffin-embedded human placenta tissue using MBS7001227 at dilution of 1:100
anti-SLC6A6 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-SLC6A6 antibody    Immunofluorescent analysis of Hela cells using MBS7001227 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-SLC6A6 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for SLC6A6. It may not necessarily be applicable to this product.
 NCBI GI #    618857458
 NCBI GeneID    6533
 NCBI Accession #    NP_001127839.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001134367.3 [Other Products]
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 UniProt Primary Accession #    P31641 [Other Products]
 UniProt Secondary Accession #    Q9BRI2; Q9BXB0; B2RNU7 [Other Products]
 UniProt Related Accession #    P31641; AAB25509 [Other Products]
 Molecular Weight    22,744 Da
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 NCBI Official Full Name    sodium- and chloride-dependent taurine transporter isoform c
 NCBI Official Synonym Full Names    solute carrier family 6 (neurotransmitter transporter), member 6
 NCBI Official Symbol    SLC6A6 [Similar Products]
 NCBI Official Synonym Symbols   
TAUT
[Similar Products]
 NCBI Protein Information    sodium- and chloride-dependent taurine transporter
 UniProt Protein Name    Sodium- and chloride-dependent taurine transporter
 UniProt Synonym Protein Names   
Solute carrier family 6 member 6
 Protein Family    Sodium- and chloride-dependent taurine transporter
 UniProt Gene Name    SLC6A6 [Similar Products]
 UniProt Entry Name    SC6A6_HUMAN
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 NCBI Summary for SLC6A6    This gene encodes a multi-pass membrane protein that is a member of a family of sodium and chloride-ion dependent transporters. The encoded protein transports taurine and beta-alanine. There is a pseudogene for this gene on chromosome 21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
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 UniProt Comments for SLC6A6    TAUT: Required for the uptake of taurine. Transports both taurine and beta-alanine which requires sodium ions. Chloride ions are necessary for optimal uptake. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.

Protein type: Transporter; Transporter, SLC family; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 3p25.1

Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane

Molecular Function: neurotransmitter:sodium symporter activity; taurine:sodium symporter activity

Biological Process: amino acid metabolic process; amino acid transport; ion transport; neurotransmitter transport; taurine transport; transmembrane transport; transport
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 Research Articles on SLC6A6    1. This is the first study to present information on the transcriptional regulation of taurine transporter gene and the localization of the taurine transporter protein in chondrocytic cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SLC6A6 antibodyPathways associated with anti-SLC6A6 antibody
 Reference Product  PubMed Publications
 SLC1A1 antibody  >1 publications with SLC6A6 and SLC1A1
 SLC38A2 antibody  >1 publications with SLC6A6 and SLC38A2
 Products by Pathway  Pathway Diagram
 Amino Acid Transport Across The Plasma Membrane Pathway antibodies  Amino Acid Transport Across The Plasma Membrane Pathway Diagram
 Na+/Cl- Dependent Neurotransmitter Transporters Pathway antibodies  Na+/Cl- Dependent Neurotransmitter Transporters Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies  Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram
 Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway antibodies  Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway Diagram
Diseases associated with anti-SLC6A6 antibodyOrgans/Tissues associated with anti-SLC6A6 antibody
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >2 publications with SLC6A6 and Fibrosis
 Mental Disorders Antibodies  >1 publications with SLC6A6 and Mental Disorders
 Cardiovascular Diseases Antibodies  >1 publications with SLC6A6 and Cardiovascular Diseases
 Atrophy Antibodies  >1 publications with SLC6A6 and Atrophy
 Hypertension Antibodies  >1 publications with SLC6A6 and Hypertension
 Cognition Disorders Antibodies  >1 publications with SLC6A6 and Cognition Disorders
 Hypertrophy Antibodies  >1 publications with SLC6A6 and Hypertrophy
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3 publications with SLC6A6 and Blood
 Eye Antibodies  >3 publications with SLC6A6 and Eye
 Testis Antibodies  >2 publications with SLC6A6 and Testis
 Muscle Antibodies  >2 publications with SLC6A6 and Muscle
 Brain Antibodies  >2 publications with SLC6A6 and Brain
 Lymph Node Antibodies  >1 publications with SLC6A6 and Lymph Node
 Ganglia Antibodies  >1 publications with SLC6A6 and Ganglia
 Intestine Antibodies  >1 publications with SLC6A6 and Intestine
 Mammary Gland Antibodies  >1 publications with SLC6A6 and Mammary Gland
 Kidney Antibodies  >1 publications with SLC6A6 and Kidney
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