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anti-SLC7A5 antibody :: Rabbit SLC7A5 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS177019
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 Product Name   

SLC7A5, Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-SLC7A5 antibody

 Product Synonym Names    Large neutral amino acids transporter small subunit 1; solute carrier family 7(amino acid transporter light chain, L system), member 5; 4F2 LC antibody; 4F2 light chain antibody; 4F2LC antibody; CD98 antibody; CD98 light chain antibody; CD98LC antibody; D16S469E antibody; DC49 antibody; E16 antibody; hLAT1 antibody; Integral membrane protein E16 antibody; L type amino acid transporter antibody; L type amino acid transporter 1 antibody; L-type amino acid transporter 1 antibody; Large neutral amino acids transporter 1 antibody; Large neutral amino acids transporter antibody; Large neutral amino acids transporter small subunit 1 antibody; LAT1 antibody; LAT1_HUMAN antibody; Membrane protein E16 antibody; MPE16 antibody; Slc7a5 antibody; Sodium independent neutral amino acid transporter antibody; Sodium independent neutral amino acid transporter LAT1 antibody; Solute carrier family 7(cationic amino acid transporter y+ system) member 5 antibody; Solute carrier family 7 member 5 antibody; TA1 antibody; Tumor associated protein 1 antibody; y+ system cationic amino acid transporter antibody
 Product Gene Name   

anti-SLC7A5 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600182
 3D Structure    ModBase 3D Structure for Q01650
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Reacts with: Human, Rat
Predicted to work with: Mouse
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 Specificity    No cross reactivity with other proteins.
 Purity/Purification    Immunogen affinity purified.
 Form/Format    Lyophilized
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 Immunogen    A synthetic peptide corresponding to a sequence at the C-terminus of human SLC7A5 (489-507aa IFSTTVLCQKLMQVVPQET), different from the related rat and mouse sequences by one amino acid.
 Contents    Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
 Reconstitution    Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
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 Preparation and Storage    At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-SLC7A5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-SLC7A5 antibody

   Description: Rabbit IgG polyclonal antibody for Large neutral amino acids transporter small subunit 1(SLC7A5) detection. Tested with WB, IHC-P, IHC-F, ICC in Human, Mouse, Rat.
Background: Solute carrier family 7 member 5, also known as Large neutral amino acids transporter small subunit 1 or SLC7A5 is a protein that in humans is encodes by the SLC7A5 gene. This gene is mapped to 16q24.2. This gene acts as an amino acid exchanger. It involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine(T3) and thyroxine(T4) across the cell membrane in tissues such as placenta. This gene plays a role in neuronal cell proliferation(neurogenesis) in brain. It involved in the uptake of methylmercury(MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity.
 Applications Tested/Suitable for anti-SLC7A5 antibody   

Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Formalin, Immunocytochemistry ICC

 Application Notes for anti-SLC7A5 antibody    Western Blot:
Concentration: 0.1-0.5ug/ml
Tested Species: Hu
Predicted Species: Ms, Rat

Immunohistochemistry (Paraffin-embedded section): Concentration: 0.5-1ug/ml
Tested Species: Hu, Rat
Predicted Species: Ms
Antigen Retrieval: By Heat

Imunohistochemistry (Frozen Section)
Concentration: 0.5-1ug/ml
Tested Species: Rat
Predicted Species: Hu, Ms

Immunocytochemistry:
Concentration:0.5-1ug/ml
Tested Species: Hu
Predicted Species: Ms, Rat

Tested Species: In-house tested species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarities.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
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 Testing Data of anti-SLC7A5 antibody    anti-SLC7A5 antibody Testing Data image
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 Testing Data #2 of anti-SLC7A5 antibody    anti-SLC7A5 antibody Testing Data #2 image
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 Testing Data #3 of anti-SLC7A5 antibody    anti-SLC7A5 antibody Testing Data #3 image
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 Testing Data #4 of anti-SLC7A5 antibody    anti-SLC7A5 antibody Testing Data #4 image
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NCBI/Uniprot data below describe general gene information for SLC7A5. It may not necessarily be applicable to this product.
 NCBI GI #    12643412
 NCBI GeneID    8140
 NCBI Accession #    Q01650.2 [Other Products]
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 UniProt Primary Accession #    Q01650 [Other Products]
 UniProt Secondary Accession #    Q8IV97; Q9UBN8; Q9UP15; Q9UQC0 [Other Products]
 UniProt Related Accession #    Q01650 [Other Products]
 Molecular Weight    55,010 Da
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 NCBI Official Full Name    Large neutral amino acids transporter small subunit 1
 NCBI Official Synonym Full Names    solute carrier family 7 (amino acid transporter light chain, L system), member 5
 NCBI Official Symbol    SLC7A5 [Similar Products]
 NCBI Official Synonym Symbols   
E16; CD98; LAT1; 4F2LC; MPE16; hLAT1; D16S469E
[Similar Products]
 NCBI Protein Information    large neutral amino acids transporter small subunit 1; 4F2 LC; 4F2 light chain; CD98 light chain; integral membrane protein E16; L-type amino acid transporter 1; solute carrier family 7 member 5; large neutral amino acids transporter 1; y+ system cationic amino acid transporter; sodium-independent neutral amino acid transporter LAT1; solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
 UniProt Protein Name    Large neutral amino acids transporter small subunit 1
 UniProt Synonym Protein Names   
4F2 light chain; 4F2 LC; 4F2LC; CD98 light chain; Integral membrane protein E16; L-type amino acid transporter 1; hLAT1; Solute carrier family 7 member 5; y+ system cationic amino acid transporter
 Protein Family    Large neutral amino acids transporter
 UniProt Gene Name    SLC7A5 [Similar Products]
 UniProt Synonym Gene Names    CD98LC; LAT1; MPE16; 4F2 LC; 4F2LC; hLAT1 [Similar Products]
 UniProt Entry Name    LAT1_HUMAN
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SLC7A5 antibodyPathways associated with anti-SLC7A5 antibody
 Reference Product  PubMed Publications
 SLC3A2 antibody  >14 publications with SLC7A5 and SLC3A2
 SLC1A5 antibody  >12 publications with SLC7A5 and SLC1A5
 SLC3A1 antibody  >1 publications with SLC7A5 and SLC3A1
 Products by Pathway  Pathway Diagram
 Amino Acid Transport Across The Plasma Membrane Pathway antibodies  Amino Acid Transport Across The Plasma Membrane Pathway Diagram
 Basigin Interactions Pathway antibodies  Basigin Interactions Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway antibodies  Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway Diagram
Diseases associated with anti-SLC7A5 antibodyOrgans/Tissues associated with anti-SLC7A5 antibody
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >26 publications with SLC7A5 and Adenocarcinoma
 Nervous System Diseases Antibodies  >21 publications with SLC7A5 and Nervous System Diseases
 Brain Diseases Antibodies  >20 publications with SLC7A5 and Brain Diseases
 Lung Diseases Antibodies  >20 publications with SLC7A5 and Lung Diseases
 Carcinoma, Squamous Cell Antibodies  >18 publications with SLC7A5 and Carcinoma, Squamous Cell
 Neoplasm Metastasis Antibodies  >15 publications with SLC7A5 and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >14 publications with SLC7A5 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >10 publications with SLC7A5 and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >8 publications with SLC7A5 and Liver Neoplasms
 Ovarian Neoplasms Antibodies  >7 publications with SLC7A5 and Ovarian Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >66 publications with SLC7A5 and Blood
 Brain Antibodies  >53 publications with SLC7A5 and Brain
 Kidney Antibodies  >26 publications with SLC7A5 and Kidney
 Lung Antibodies  >25 publications with SLC7A5 and Lung
 Liver Antibodies  >15 publications with SLC7A5 and Liver
 Muscle Antibodies  >15 publications with SLC7A5 and Muscle
 Eye Antibodies  >12 publications with SLC7A5 and Eye
 Lymph Antibodies  >12 publications with SLC7A5 and Lymph
 Lymph Node Antibodies  >11 publications with SLC7A5 and Lymph Node
 Intestine Antibodies  >9 publications with SLC7A5 and Intestine
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