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anti-SNAP29 antibody :: Rabbit anti-Human SNAP29 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7046564
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SNAP29, Polyclonal Antibody

★Popular Item★
 Also Known As   

SNAP29 Antibody

 Product Synonym Names    Synaptosomal-associated protein 29Imported; Soluble 29 kDa NSF attachment protein; SNAP29
 Product Gene Name   

anti-SNAP29 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    604202
 3D Structure    ModBase 3D Structure for O95721
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human Synaptosomal-associated protein 29 protein (1-258AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-SNAP29 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SNAP29 antibody

   SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Plays also a role in ciliogenesis by regulating membrane fusions.
 Applications Tested/Suitable for anti-SNAP29 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-SNAP29 antibody    Western blot
All lanes: SNAP29 antibody at 1.79 ug/ml
Lane 1: 293T whole cell lysate
Lane 2: Jurkat whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 29 kDa
Observed band size: 29 kDa

anti-SNAP29 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-SNAP29 antibody    Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7046564 at dilution 1:100
anti-SNAP29 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-SNAP29 antibody    Immunohistochemistry of paraffin-embedded human gastric cancer using MBS7046564 at dilution 1:100
anti-SNAP29 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for SNAP29. It may not necessarily be applicable to this product.
 NCBI GI #    4759154
 NCBI GeneID    9342
 NCBI Accession #    NP_004773.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004782.3 [Other Products]
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 UniProt Primary Accession #    O95721 [Other Products]
 UniProt Related Accession #    O95721 [Other Products]
 Molecular Weight    28,970 Da
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 NCBI Official Full Name    synaptosomal-associated protein 29
 NCBI Official Synonym Full Names    synaptosome associated protein 29
 NCBI Official Symbol    SNAP29 [Similar Products]
 NCBI Official Synonym Symbols   
CEDNIK; SNAP-29
[Similar Products]
 NCBI Protein Information    synaptosomal-associated protein 29
 UniProt Protein Name    Synaptosomal-associated protein 29
 UniProt Synonym Protein Names   
Soluble 29 kDa NSF attachment protein
 Protein Family    SNAP25 homologous protein
 UniProt Gene Name    SNAP29 [Similar Products]
 UniProt Synonym Gene Names    SNAP-29 [Similar Products]
 UniProt Entry Name    SNP29_HUMAN
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 NCBI Summary for SNAP29    This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for SNAP29    SNAP29: Involved in multiple membrane trafficking steps. Defects in SNAP29 are the cause of CEDNIK syndrome (CEDNIK). CEDNIK is a neurocutaneous syndrome characterized by cerebral dysgenesis, neuropathy, ichthyosis and palmoplantar keratoderma. Belongs to the SNAP-25 family.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 22q11.21

Cellular Component: centrosome; cytoplasm; Golgi membrane; plasma membrane; SNARE complex

Molecular Function: protein binding; SNAP receptor activity; syntaxin binding

Biological Process: cilium biogenesis; exocytosis; synaptic vesicle fusion to presynaptic membrane; synaptic vesicle priming; vesicle targeting

Disease: Cerebral Dysgenesis, Neuropathy, Ichthyosis, And Palmoplantar Keratoderma Syndrome
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 Research Articles on SNAP29    1. support a role of Snap29 at key steps of membrane trafficking, and predict that signaling defects may contribute to the pathogenesis of cerebral dysgenesis
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-SNAP29 antibodyDiseases associated with anti-SNAP29 antibody
 Products by Pathway  Pathway Diagram
 Intra-Golgi And Retrograde Golgi-to-ER Traffic Pathway antibodies  Intra-Golgi And Retrograde Golgi-to-ER Traffic Pathway Diagram
 Intra-Golgi Traffic Pathway antibodies  Intra-Golgi Traffic Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 SNARE Interactions In Vesicular Transport Pathway antibodies  SNARE Interactions In Vesicular Transport Pathway Diagram
 SNARE Interactions In Vesicular Transport Pathway antibodies  SNARE Interactions In Vesicular Transport Pathway Diagram
 Vesicle-mediated Transport Pathway antibodies  Vesicle-mediated Transport Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >7 publications with SNAP29 and Nervous System Diseases
 Heart Diseases Antibodies  >4 publications with SNAP29 and Heart Diseases
 Cardiovascular Diseases Antibodies  >4 publications with SNAP29 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >3 publications with SNAP29 and Disease Models, Animal
 Brain Diseases Antibodies  >2 publications with SNAP29 and Brain Diseases
 Seizures Antibodies  >2 publications with SNAP29 and Seizures
 Learning Disorders Antibodies  >2 publications with SNAP29 and Learning Disorders
 Cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome Antibodies  >2 publications with SNAP29 and Cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome
 Depressive Disorder Antibodies  >1 publications with SNAP29 and Depressive Disorder
 Necrosis Antibodies  >1 publications with SNAP29 and Necrosis
Organs/Tissues associated with anti-SNAP29 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with SNAP29 and Brain
 Blood Antibodies  >4 publications with SNAP29 and Blood
 Eye Antibodies  >4 publications with SNAP29 and Eye
 Heart Antibodies  >3 publications with SNAP29 and Heart
 Skin Antibodies  >3 publications with SNAP29 and Skin
 Embryonic Tissue Antibodies  >3 publications with SNAP29 and Embryonic Tissue
 Kidney Antibodies  >3 publications with SNAP29 and Kidney
 Liver Antibodies  >2 publications with SNAP29 and Liver
 Ovary Antibodies  >1 publications with SNAP29 and Ovary
 Uncharacterized Tissue Antibodies  >1 publications with SNAP29 and Uncharacterized Tissue
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