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anti-SNCG antibody :: Rabbit SNCG Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS129065
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.1 mL  /  $305 +1 FREE 8GB USB
0.2 mL  /  $460 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SNCG, Polyclonal Antibody

★Popular Item★
 Also Known As   

SNCG Polyclonal Antibody

 Product Synonym Names    SR; BCSG1
 Product Gene Name   

anti-SNCG antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602998
 3D Structure    ModBase 3D Structure for O76070
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Affinity Purification
 Concentration    1mg/ml (lot specific)
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 Species    Human
 Immunogen    Recombinant Protein
 Immunogen    Recombinant protein of human SNCG
 Calculated Molecular Weight    13kDa
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 Preparation and Storage    Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Other Notes    Small volumes of anti-SNCG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SNCG antibody

   This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development.
 Product Categories/Family for anti-SNCG antibody    Polyclonal
 Applications Tested/Suitable for anti-SNCG antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

 Application Notes for anti-SNCG antibody    WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
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 Western Blot (WB) of anti-SNCG antibody    Western blot analysis of extracts of various cell lines, using SNCG antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 60s.
anti-SNCG antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-SNCG antibody    Immunohistochemistry of paraffin-embedded human thyroid cancer using SNCG antibody at dilution of 1:200 (40x lens).
anti-SNCG antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-SNCG antibody    Immunofluorescence analysis of U2OS cells using SNCG antibody. Blue: DAPI for nuclear staining.
anti-SNCG antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for SNCG. It may not necessarily be applicable to this product.
 NCBI GI #    90110074
 NCBI GeneID    6623
 NCBI Accession #    O76070.2 [Other Products]
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 UniProt Primary Accession #    O76070 [Other Products]
 UniProt Secondary Accession #    O15104; Q96P61 [Other Products]
 UniProt Related Accession #    O76070 [Other Products]
 Molecular Weight    127
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 NCBI Official Full Name    Gamma-synuclein
 NCBI Official Synonym Full Names    synuclein, gamma (breast cancer-specific protein 1)
 NCBI Official Symbol    SNCG [Similar Products]
 NCBI Official Synonym Symbols   
SR; BCSG1
[Similar Products]
 NCBI Protein Information    gamma-synuclein; persyn; synoretin; breast cancer-specific gene 1 protein
 UniProt Protein Name    Gamma-synuclein
 UniProt Synonym Protein Names   
Breast cancer-specific gene 1 protein; Persyn; Synoretin; SR
 Protein Family    Gamma-synuclein
 UniProt Gene Name    SNCG [Similar Products]
 UniProt Synonym Gene Names    BCSG1; PERSYN; PRSN; SR [Similar Products]
 UniProt Entry Name    SYUG_HUMAN
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 NCBI Summary for SNCG    This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development. [provided by RefSeq, Jan 2010]
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 UniProt Comments for SNCG    SNCG: a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. May be involved in modulating axonal architecture during development and in the adult. Plays a role in neurofilament network integrity. High levels have been identified in advanced breast carcinomas.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 10q23.2-q23.3

Cellular Component: cell soma; perinuclear region of cytoplasm; cytoplasm; plasma membrane; microtubule organizing center; spindle; nerve terminal

Molecular Function: beta-tubulin binding; alpha-tubulin binding

Biological Process: response to drug; synaptic transmission; adult locomotory behavior; protein secretion; regulation of neurotransmitter secretion; synapse organization and biogenesis; response to cocaine; regulation of dopamine secretion
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 Research Articles on SNCG    1. SNCG is actively secreted by cancer cells via an unconventional secretion pathway and contributes to aggressive phenotypes of cancer cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SNCG antibodyDiseases associated with anti-SNCG antibody
 Reference Product  PubMed Publications
 EXT2 antibody  >1 publications with SNCG and EXT2
 FABP4 antibody  >1 publications with SNCG and FABP4
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >36 publications with SNCG and Breast Neoplasms
 Carcinoma Antibodies  >27 publications with SNCG and Carcinoma
 Nervous System Diseases Antibodies  >15 publications with SNCG and Nervous System Diseases
 Adenocarcinoma Antibodies  >15 publications with SNCG and Adenocarcinoma
 Liver Neoplasms Antibodies  >8 publications with SNCG and Liver Neoplasms
 Movement Disorders Antibodies  >7 publications with SNCG and Movement Disorders
 Disease Models, Animal Antibodies  >5 publications with SNCG and Disease Models, Animal
 Liver Diseases Antibodies  >5 publications with SNCG and Liver Diseases
 Neoplasms, Experimental Antibodies  >4 publications with SNCG and Neoplasms, Experimental
 Lung Neoplasms Antibodies  >3 publications with SNCG and Lung Neoplasms
Organs/Tissues associated with anti-SNCG antibody
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >32 publications with SNCG and Nerve
 Brain Antibodies  >12 publications with SNCG and Brain
 Liver Antibodies  >11 publications with SNCG and Liver
 Eye Antibodies  >6 publications with SNCG and Eye
 Prostate Antibodies  >5 publications with SNCG and Prostate
 Lung Antibodies  >5 publications with SNCG and Lung
 Ovary Antibodies  >3 publications with SNCG and Ovary
 Bladder Antibodies  >3 publications with SNCG and Bladder
 Adipose Tissue Antibodies  >2 publications with SNCG and Adipose Tissue
 Muscle Antibodies  >2 publications with SNCG and Muscle
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