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anti-SNX18 antibody :: Goat SNX18/SNAG1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS420077
Western Blot (WB)
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SNX18/SNAG1, Polyclonal Antibody

 Also Known As   

Goat anti-SNX18/SNAG1 Antibody

 Product Synonym Names    SNX18; SNAG1; sorting nexin associated golgi protein 1; sorting nexin 18; FLJ11997; FLJ32560; FLJ61062; MGC150827; MGC150829; SH3PX2; SH3PXD3B; SH3 and PX domain-containing protein 3B; SNX18 antibody; SNAG1 antibody; sorting nexin associated golgi protein 1 antibody; sorting nexin 18 antibody; FLJ11997 antibody; FLJ32560 antibody; FLJ61062 antibody; MGC150827 antibody; MGC150829 antibody; SH3PX2 antibody; SH3PXD3B antibody; SH3 and PX domain-containing protein 3B antibody; SNX18 / SNAG1
 Product Gene Name   

anti-SNX18 antibody

[Similar Products]
 Product Synonym Gene Name    SNAG1 [Similar Products]
 Antibody/Peptide Pairs    SNX18 / SNAG1 peptide (MBS425801) is used for blocking the activity of SNX18/SNAG1 antibody (MBS420077)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    KVQRVPLMTV LSF
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human; Expected from sequence similarity: Human
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-KVQRVPLMTVLSF, from the C Terminus of the protein sequence according to NP_443102.2.
 Epitope    C Terminus
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-SNX18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-SNX18 antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-SNX18 antibody    Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Approx 80kDa double band observed in lysates of cell line A549 (calculated MW of 72.2kDa according to NP_443102.2). The observed bands are inferred to be post-translational modifications. Recommended concentration: 1-3ug/ml.
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 Western Blot (WB) of anti-SNX18 antibody    (1ug/ml) staining of A549 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-SNX18 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for SNX18. It may not necessarily be applicable to this product.
 NCBI GI #    157057543
 NCBI GeneID    112574
 NCBI Accession #    NP_443102.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_052870.2 [Other Products]
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 UniProt Secondary Accession #    Q05BB3; Q0VG02; B4E2B3; H7BXX3 [Other Products]
 UniProt Related Accession #    Q96RF0 [Other Products]
 Molecular Weight    64,752 Da
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 NCBI Official Full Name    sorting nexin-18 isoform b
 NCBI Official Synonym Full Names    sorting nexin 18
 NCBI Official Symbol    SNX18 [Similar Products]
 NCBI Official Synonym Symbols   
SNAG1; SH3PX2; SH3PXD3B
[Similar Products]
 NCBI Protein Information    sorting nexin-18
 UniProt Protein Name    Sorting nexin-18
 UniProt Synonym Protein Names   
SH3 and PX domain-containing protein 3B; Sorting nexin-associated Golgi protein 1
 Protein Family    Sorting nexin
 UniProt Gene Name    SNX18 [Similar Products]
 UniProt Synonym Gene Names    SH3PXD3B; SNAG1 [Similar Products]
 UniProt Entry Name    SNX18_HUMAN
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 NCBI Summary for SNX18    This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for SNX18    SNX18: May be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane. Belongs to the sorting nexin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 5q11.2

Cellular Component: clathrin-coated vesicle; cytoplasmic membrane-bound vesicle; cytoplasmic vesicle membrane; endosome; endosome membrane; extrinsic to internal side of plasma membrane; intracellular membrane-bound organelle; nucleoplasm

Molecular Function: phosphatidylinositol-4,5-bisphosphate binding; protein binding

Biological Process: cytokinesis after mitosis; endocytosis; endosome transport; intracellular protein transport; mitosis; positive regulation of GTPase activity; vesicle organization and biogenesis
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 Research Articles on SNX18    1. SNX18 promotes autophagosome formation by virtue of its ability to remodel membranes and provide membrane to forming autophagosomes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-SNX18 antibodyOrgans/Tissues associated with anti-SNX18 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1 publications with SNX18 and Nervous System Diseases
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1 publications with SNX18 and Kidney
 Intestine Antibodies  >1 publications with SNX18 and Intestine
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