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anti-SNX18 antibody :: Rabbit anti-Human, Mouse SNX18 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7046550
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SNX18, Polyclonal Antibody

★Popular Item★
 Also Known As   

SNX18 Antibody

 Product Synonym Names    Sorting nexin-18; SH3 and PX domain-containing protein 3B; Sorting nexin-associated Golgi protein 1; SNX18; SH3PXD3B; SNAG1
 Product Gene Name   

anti-SNX18 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q96RF0
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human Sorting nexin-18 protein (C-180AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-165518
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-SNX18 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SNX18 antibody

   Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane.
 Applications Tested/Suitable for anti-SNX18 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-SNX18 antibody    Western blot
All lanes: SNX18 antibody at 1.6ug/ml
Lane 1: A549 whole cell lysate
Lane 2: Hela whole cell lysate
Lane 3: Mouse kidney tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 69,70,65 kDa
Observed band size: 69 kDa

anti-SNX18 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-SNX18 antibody    Immunohistochemistry of paraffin-embedded human tonsil tissue MBS7046550 at dilution 1:100
anti-SNX18 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-SNX18 antibody    Immunohistochemistry of paraffin-embedded human small intestine MBS7046550 at dilution 1:100
anti-SNX18 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for SNX18. It may not necessarily be applicable to this product.
 NCBI GI #    157057545
 NCBI GeneID    112574
 NCBI Accession #    NP_001096045.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001102575.1 [Other Products]
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 UniProt Primary Accession #    Q96RF0 [Other Products]
 UniProt Secondary Accession #    Q05BB3; Q0VG02; B4E2B3; H7BXX3 [Other Products]
 Molecular Weight    64,752 Da
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 NCBI Official Full Name    sorting nexin-18 isoform a
 UniProt Protein Name    Sorting nexin-18
 UniProt Synonym Protein Names   
SH3 and PX domain-containing protein 3B; Sorting nexin-associated Golgi protein 1
 Protein Family    Sorting nexin
 UniProt Gene Name    SNX18 [Similar Products]
 UniProt Synonym Gene Names    SH3PXD3B; SNAG1 [Similar Products]
 UniProt Entry Name    SNX18_HUMAN
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 UniProt Comments for SNX18    SNX18: May be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane. Belongs to the sorting nexin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 5q11.2

Cellular Component: clathrin-coated vesicle; cytoplasmic membrane-bound vesicle; endosome; extrinsic to internal side of plasma membrane; intracellular membrane-bound organelle; nucleoplasm

Molecular Function: phosphatidylinositol-4,5-bisphosphate binding; protein binding

Biological Process: cytokinesis after mitosis; endocytosis; endosome transport; positive regulation of GTPase activity; vesicle organization and biogenesis
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-SNX18 antibodyOrgans/Tissues associated with anti-SNX18 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1 publications with SNX18 and Nervous System Diseases
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1 publications with SNX18 and Kidney
 Intestine Antibodies  >1 publications with SNX18 and Intestine
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