NP_055241.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
13,349 Da
NCBI Official Full Name
sorting nexin-5 isoform a
NCBI Official Synonym Full Names
sorting nexin 5
NCBI Protein Information
sorting nexin-5
UniProt Protein Name
Sorting nexin-5
UniProt Entry Name
SNX5_HUMAN
NCBI Summary for SNX5
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein functions in endosomal sorting, the phosphoinositide-signaling pathway, and macropinocytosis. This gene may play a role in the tumorigenesis of papillary thyroid carcinoma. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]
UniProt Comments for SNX5
SNX5: May be involved in several stages of intracellular trafficking. Plays a role in macropinocytosis. Plays a role in the internalization of EGFR after EGF stimulation. Belongs to the sorting nexin family.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 20p11
Cellular Component: cytoplasmic vesicle membrane; cytosol; early endosome membrane; extrinsic to internal side of plasma membrane; phagocytic cup; retromer complex; ruffle
Molecular Function: phosphoinositide binding; protein binding; protein heterodimerization activity
Biological Process: intracellular protein transport; pinocytosis; regulation of macroautophagy; retrograde transport, endosome to Golgi; vesicle organization and biogenesis
Research Articles on SNX5
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Products associated with anti-SNX5 antibody
Pathways associated with anti-SNX5 antibody
Diseases associated with anti-SNX5 antibody
Organs/Tissues associated with anti-SNX5 antibody
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