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anti-SPINT1/HAI-1 antibody :: Rabbit SPINT1/HAI-1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7604415 (SPECIAL PROMOTIONAL PRICING for a limited time)
Unit / Price
0.1 mg  /  $180 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SPINT1/HAI-1, Polyclonal Antibody

★Popular Item★
 Also Known As   

SPINT1/HAI-1 Rabbit Polyclonal

 Product Synonym Names    HAI, HAI 1, HAI1, MANSC2, SPINT1
 Product Gene Name   

anti-SPINT1/HAI-1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse; other species are not tested. Please decide the specificity by homology
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 Purity/Purification    >=95% as determined by SDS-PAGE
Immunogen Affinity Purified
 Form/Format    Liquid
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 Immunogen    Serine peptidase inhibitor, Kunitz type 1
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 Preparation and Storage    PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-SPINT1/HAI-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-SPINT1/HAI-1 antibody

   Inhibitor of HGF activator. Also acts as an inhibitor of matriptase (ST14).
 Applications Tested/Suitable for anti-SPINT1/HAI-1 antibody   

ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)

 Application Notes for anti-SPINT1/HAI-1 antibody    WB: 1:200-1:1000
IHC: 1:50-1:500
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 Western blot of anti-SPINT1/HAI-1 antibody    Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using MBS7604415 ( HAI-1 Antibody) at dilution of 1:200
anti-SPINT1/HAI-1 antibody Western blot image
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 SDS-PAGE of anti-SPINT1/HAI-1 antibody    human placenta tissue were subjected to SDS PAGE followed by western blot with MBS7604415 ( HAI-1 Antibody) at dilution of 1:300
anti-SPINT1/HAI-1 antibody SDS-PAGE image
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NCBI/Uniprot data below describe general gene information for SPINT1/HAI-1. It may not necessarily be applicable to this product.
 NCBI GI #    13543203
 NCBI GeneID    20732
 NCBI Accession #    AAH05769.1 [Other Products]
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 UniProt Secondary Accession #    Q99J04 [Other Products]
 UniProt Related Accession #    Q9R097 [Other Products]
 Molecular Weight    58kd
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 NCBI Official Full Name    Spint1 protein
 NCBI Official Synonym Full Names    serine protease inhibitor, Kunitz type 1
 NCBI Official Symbol    Spint1 [Similar Products]
 NCBI Official Synonym Symbols   
HAI-1
[Similar Products]
 NCBI Protein Information    kunitz-type protease inhibitor 1
 UniProt Protein Name    Kunitz-type protease inhibitor 1
 UniProt Synonym Protein Names   
Hepatocyte growth factor activator inhibitor type 1; HAI-1
 UniProt Gene Name    Spint1 [Similar Products]
 UniProt Synonym Gene Names    Hai1; HAI-1 [Similar Products]
 UniProt Entry Name    SPIT1_MOUSE
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 UniProt Comments for SPINT1/HAI-1    SPINT1: Inhibitor of HGF activator. Also acts as an inhibitor of matriptase (ST14). 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular region; extracellular space; plasma membrane

Molecular Function: protease inhibitor activity; serine-type endopeptidase inhibitor activity

Biological Process: embryonic placenta development; extracellular matrix organization and biogenesis; negative regulation of peptidase activity; neural tube closure; positive regulation of glial cell differentiation
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 Research Articles on SPINT1/HAI-1    1. HAI-1 may have a critical role in maintaining normal keratinocyte morphology through regulation of PAR-2-dependent p38 mitogen-activated protein kinase signaling.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-SPINT1/HAI-1 antibodyDiseases associated with anti-SPINT1/HAI-1 antibody
 Products by Pathway  Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >16 publications with SPINT1/HAI-1 and Adenocarcinoma
 Neoplasm Metastasis Antibodies  >14 publications with SPINT1/HAI-1 and Neoplasm Metastasis
 Hyperplasia Antibodies  >7 publications with SPINT1/HAI-1 and Hyperplasia
 Lung Neoplasms Antibodies  >7 publications with SPINT1/HAI-1 and Lung Neoplasms
 Inflammation Antibodies  >7 publications with SPINT1/HAI-1 and Inflammation
 Cell Transformation, Neoplastic Antibodies  >6 publications with SPINT1/HAI-1 and Cell Transformation, Neoplastic
 Liver Diseases Antibodies  >6 publications with SPINT1/HAI-1 and Liver Diseases
 Ovarian Neoplasms Antibodies  >6 publications with SPINT1/HAI-1 and Ovarian Neoplasms
 Embryo Loss Antibodies  >5 publications with SPINT1/HAI-1 and Embryo Loss
 Fibrosis Antibodies  >4 publications with SPINT1/HAI-1 and Fibrosis
Organs/Tissues associated with anti-SPINT1/HAI-1 antibody
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >12 publications with SPINT1/HAI-1 and Skin
 Liver Antibodies  >12 publications with SPINT1/HAI-1 and Liver
 Embryonic Tissue Antibodies  >12 publications with SPINT1/HAI-1 and Embryonic Tissue
 Lung Antibodies  >11 publications with SPINT1/HAI-1 and Lung
 Kidney Antibodies  >9 publications with SPINT1/HAI-1 and Kidney
 Mammary Gland Antibodies  >8 publications with SPINT1/HAI-1 and Mammary Gland
 Intestine Antibodies  >7 publications with SPINT1/HAI-1 and Intestine
 Stomach Antibodies  >6 publications with SPINT1/HAI-1 and Stomach
 Brain Antibodies  >4 publications with SPINT1/HAI-1 and Brain
 Ovary Antibodies  >2 publications with SPINT1/HAI-1 and Ovary
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