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anti-SRC antibody :: Rabbit SRC Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2530127
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SRC, Polyclonal Antibody

★Popular Item★
 Also Known As   

SRC Polyclonal Antibody

 Product Synonym Names    ASV; SRC1; c-SRC; p60-Src
 Product Gene Name   

anti-SRC antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen affinity purification
 Concentration    0.5mg/mL (lot specific)
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 Immunogen    Recombinant protein of human SRC
 Calculated Molecular Weight: 60kDa   
 Buffer    PBS with 0.05% sodium azide, 50% glycerol, pH7.3
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 Preparation and Storage    Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-SRC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SRC antibody

   This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
 Product Categories/Family for anti-SRC antibody    Cancer; Epigenetics
 Applications Tested/Suitable for anti-SRC antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-SRC antibody    WB: 1:200-1:1000
IHC: 1:15-1:50
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 Western Blot (WB) of anti-SRC antibody    Western Blot analysis of PC3 cell using SRC Polyclonal Antibody at dilution of 1:100
anti-SRC antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-SRC antibody    Immunohistochemistry of paraffin-embedded Human liver cancer using SRC Polyclonal Antibody at dilution of 1:10
anti-SRC antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-SRC antibody    Immunohistochemistry of paraffin-embedded Human esophagus cancer using SRC Polyclonal Antibody at dilution of 1:10
anti-SRC antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for SRC. It may not necessarily be applicable to this product.
 NCBI GI #    62635494
 NCBI GeneID    20779
 NCBI Accession #    AAX90616.1 [Other Products]
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 UniProt Secondary Accession #    Q2M4I4 [Other Products]
 UniProt Related Accession #    P05480 [Other Products]
 Molecular Weight    60,645 Da
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 NCBI Official Full Name    Src
 NCBI Official Synonym Full Names    Rous sarcoma oncogene
 NCBI Official Symbol    Src [Similar Products]
 NCBI Official Synonym Symbols   
AW259666; pp60c-src
[Similar Products]
 NCBI Protein Information    neuronal proto-oncogene tyrosine-protein kinase Src; p60-Src; proto-oncogene c-Src
 UniProt Protein Name    Neuronal proto-oncogene tyrosine-protein kinase Src
 UniProt Synonym Protein Names   
Proto-oncogene c-Src; pp60c-src; p60-Src
 Protein Family    Src-like-adapter
 UniProt Gene Name    Src [Similar Products]
 UniProt Synonym Gene Names    p60-Src [Similar Products]
 UniProt Entry Name    SRC_MOUSE
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 UniProt Comments for SRC    Src: proto-oncogenic cytoplasmic tyrosine kinase of the SRC family. Highly expressed in certain fully differentiated cells such as neurons, platelets and macrophages. Phosphorylation of an activation loop tyrosine activates the enzyme; phosphorylation of a tyrosine in the C-terminus by Csk inhibits the enzyme. Two alternatively spliced isoforms have been described.

Protein type: Protein kinase, tyrosine (non-receptor); Protein kinase, TK; EC 2.7.10.2; Oncoprotein; Kinase, protein; TK group; Src family

Cellular Component: extrinsic to internal side of plasma membrane; cytoskeleton; mitochondrion; membrane; perinuclear region of cytoplasm; cytoplasm; mitochondrial inner membrane; plasma membrane; actin filament; caveola; intracellular; nucleus

Molecular Function: transferase activity; protein domain specific binding; protein binding; ephrin receptor binding; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; non-membrane spanning protein tyrosine kinase activity; kinase activity; ATP binding; hormone receptor binding; protein kinase activity

Biological Process: epidermal growth factor receptor signaling pathway; oogenesis; regulation of estrogen receptor signaling pathway; cell migration; progesterone receptor signaling pathway; peptidyl-tyrosine phosphorylation; immune system process; regulation of cell cycle; platelet-derived growth factor receptor signaling pathway; uterus development; cell cycle; protein amino acid phosphorylation; regulation of cell proliferation; regulation of protein binding; forebrain development; innate immune response; cell adhesion; phosphorylation; bone resorption
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 Research Articles on SRC    1. Data indicate that Src kinase modulates the transit time of NEDD9 (neural precursor cell expressed developmentally down-regulated gene 9) at focal adhesion sites.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SRC antibodyPathways associated with anti-SRC antibody
 Reference Product  PubMed Publications
 Egf antibody  >1236 publications with SRC and Egf
 Stat3 antibody  >808 publications with SRC and Stat3
 Ptk2 antibody  >618 publications with SRC and Ptk2
 Cbl antibody  >494 publications with SRC and Cbl
 Rac1 antibody  >413 publications with SRC and Rac1
 Pxn antibody  >175 publications with SRC and Pxn
 Bcar1 antibody  >167 publications with SRC and Bcar1
 Ptpn1 antibody  >70 publications with SRC and Ptpn1
 Nras antibody  >11 publications with SRC and Nras
 Products by Pathway  Pathway Diagram
 ADP Signalling Through P2Y Purinoceptor 1 Pathway antibodies  ADP Signalling Through P2Y Purinoceptor 1 Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram
 CD28 Co-stimulation Pathway antibodies  CD28 Co-stimulation Pathway Diagram
Diseases associated with anti-SRC antibodyOrgans/Tissues associated with anti-SRC antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >1088 publications with SRC and Breast Neoplasms
 Inflammation Antibodies  >833 publications with SRC and Inflammation
 Disease Models, Animal Antibodies  >813 publications with SRC and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >771 publications with SRC and Cardiovascular Diseases
 Neoplasms, Experimental Antibodies  >771 publications with SRC and Neoplasms, Experimental
 Nervous System Diseases Antibodies  >685 publications with SRC and Nervous System Diseases
 Neoplasm Metastasis Antibodies  >647 publications with SRC and Neoplasm Metastasis
 Necrosis Antibodies  >612 publications with SRC and Necrosis
 Neoplasm Invasiveness Antibodies  >563 publications with SRC and Neoplasm Invasiveness
 Brain Diseases Antibodies  >498 publications with SRC and Brain Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2058 publications with SRC and Brain
 Bone Antibodies  >1342 publications with SRC and Bone
 Kidney Antibodies  >1148 publications with SRC and Kidney
 Lung Antibodies  >1067 publications with SRC and Lung
 Bone Marrow Antibodies  >704 publications with SRC and Bone Marrow
 Embryonic Tissue Antibodies  >534 publications with SRC and Embryonic Tissue
 Skin Antibodies  >404 publications with SRC and Skin
 Eye Antibodies  >342 publications with SRC and Eye
 Intestine Antibodies  >295 publications with SRC and Intestine
 Ovary Antibodies  >237 publications with SRC and Ovary
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