BAA02854
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ST2L protein
NCBI Official Synonym Full Names
interleukin 1 receptor-like 1
NCBI Official Synonym Symbols
T1; St2; DER4; Ly84; ST2L; Fit-1; T1/ST2; St2-rs1 [Similar Products]
NCBI Protein Information
interleukin-1 receptor-like 1; lymphocyte antigen 84
UniProt Protein Name
Interleukin-1 receptor-like 1
UniProt Synonym Protein Names
Lymphocyte antigen 84; Protein ST2; Protein T1
UniProt Synonym Gene Names
UniProt Entry Name
ILRL1_MOUSE
UniProt Comments for Il1rl1
IL1RL1: receptor for IL33. Its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of ERK1 and/or ERK2, p38-alpha, and JNK1. Apparently promotes the activation and differentiation of T-helper 2 cells. Belongs to the interleukin-1 receptor family. Highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. Three isoforms of the human protein are produced by alternative splicing. Isoform A is prevalently expressed in the lung, testis, placenta, stomach and colon. Isoform B is more abundant in the brain, kidney and the liver. Isoform C is not detected in brain, heart, liver, kidney and skeletal muscle.
Protein type: Membrane protein, integral; Receptor, cytokine
Cellular Component: proteinaceous extracellular matrix; extracellular space; cell surface; membrane; integral to membrane; plasma membrane; extracellular region; external side of plasma membrane
Molecular Function: interleukin-1 receptor activity
Biological Process: negative regulation of cell proliferation; negative regulation of T-helper 1 type immune response; negative regulation of interferon-gamma production; negative regulation of I-kappaB kinase/NF-kappaB cascade; signal transduction; positive regulation of interleukin-5 production; positive regulation of macrophage activation; positive regulation of inflammatory response
Research Articles on Il1rl1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with anti-Il1rl1 antibody
Organs/Tissues associated with anti-Il1rl1 antibody
|