NP_001123631.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
storkhead-box protein 1 isoform b
NCBI Official Synonym Full Names
storkhead box 1
NCBI Protein Information
storkhead-box protein 1
UniProt Protein Name
Storkhead-box protein 1
UniProt Synonym Protein Names
Winged-helix domain-containing protein
UniProt Synonym Gene Names
UniProt Entry Name
STOX1_HUMAN
NCBI Summary for STOX1
The protein encoded by this gene may function as a DNA binding protein. Mutations in this gene are associated with pre-eclampsia/eclampsia 4 (PEE4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
UniProt Comments for STOX1
STOX1: Defects in STOX1 are the cause of pre-eclampsia/eclampsia 4 (PEE4); also known as gestational proteinuric hypertension. Preeclampsia is a pregnancy-associated disease with maternal symptoms but placental origin. Unlike most other human disorders, it impacts 2 individuals, the mother and her child, both of whom can be severely affected. The pathological mechanism of PEE4 involves the loss of function of STOX1 in the placenta. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Nucleolus
Chromosomal Location of Human Ortholog: 10q22.1
Cellular Component: cell cortex; centrosome; cytoplasm; nucleolus; nucleoplasm; nucleus
Molecular Function: protein binding
Biological Process: cell division; inner ear development; mitosis; positive regulation of cell proliferation; positive regulation of epithelial cell proliferation; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein kinase B signaling cascade; regulation of gene expression; regulation of mitochondrial membrane potential; transcription, DNA-dependent
Disease: Preeclampsia/eclampsia 4
Research Articles on STOX1
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Products associated with anti-STOX1 antibody
Diseases associated with anti-STOX1 antibody
Organs/Tissues associated with anti-STOX1 antibody
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