NP_071936.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
sin3 histone deacetylase corepressor complex component SDS3
NCBI Official Synonym Full Names
suppressor of defective silencing 3 homolog (S. cerevisiae)
NCBI Official Synonym Symbols
NCBI Protein Information
sin3 histone deacetylase corepressor complex component SDS3; sin3A-associated protein, 45kDa; 45 kDa Sin3-associated polypeptide; suppressor of defective silencing 3 protein homolog
UniProt Protein Name
Sin3 histone deacetylase corepressor complex component SDS3
UniProt Synonym Protein Names
45 kDa Sin3-associated polypeptide; Suppressor of defective silencing 3 protein homolog
UniProt Synonym Gene Names
UniProt Entry Name
SDS3_HUMAN
NCBI Summary for SUDS3
SDS3 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).[supplied by OMIM, Mar 2008]
UniProt Comments for SUDS3
SDS3: component of the Sin3/histone deacetylase corepressor complex. Essential for pericentric heterochromatin formation and chromosome segregation in mammalian cells.
Protein type: Helicase
Chromosomal Location of Human Ortholog: 12q24.23
Cellular Component: nucleoplasm; Sin3 complex; cytoplasm; nucleus
Molecular Function: protein binding; protein homodimerization activity; enzyme binding; histone deacetylase binding; histone deacetylase activity
Biological Process: establishment and/or maintenance of chromatin architecture; substantia nigra development; transcription, DNA-dependent; positive regulation of apoptosis; apoptosis; negative regulation of gene expression, epigenetic; gene expression; histone deacetylation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; regulation of gene expression, epigenetic
Research Articles on SUDS3
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Products associated with anti-SUDS3 antibody
Diseases associated with anti-SUDS3 antibody
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