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anti-SHBG antibody :: Rabbit Sex hormone-binding globulin Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1488811
Western Blot (WB)
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Sex hormone-binding globulin (SHBG), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human Sex hormone-binding globulin polyclonal Antibody

 Product Synonym Names    Sex steroid-binding protein Testis-specific androgen-binding protein Testosterone-estradiol-binding globulin Testosterone-estrogen-binding globulin SHBG
 Product Gene Name   

anti-SHBG antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    182205
 3D Structure    ModBase 3D Structure for P04278
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human. Other species are not tested. Please decide the specificity by homology.
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Sex hormone-binding globulin protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-32467 / sc-32468 / sc-32891 / sc-32890
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-SHBG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-SHBG antibody

   Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
 Applications Tested/Suitable for anti-SHBG antibody   

ELISA (EIA), Western Blot (WB)

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 Western Blot (WB) of anti-SHBG antibody    Western blot
All lanes: Sex hormone-binding globulin Antibody at 2ug/ml
Lane 1:Hela whole cell lysate
Lane 2:NIH3T3 whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 44,32,33,42 kDa
Observed band size: 44 kDa

anti-SHBG antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for SHBG. It may not necessarily be applicable to this product.
 NCBI GI #    7382460
 NCBI GeneID    6462
 NCBI Accession #    NP_001031.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001040.4 [Other Products]
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 UniProt Primary Accession #    P04278 [Other Products]
 UniProt Secondary Accession #    P14689; Q16616; Q3MIL0; Q6ISD2; B0FWH4; E9PGW1; F5H5Z8; I3L1N7 [Other Products]
 UniProt Related Accession #    P04278 [Other Products]
 Molecular Weight    41,712 Da [Similar Products]
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 NCBI Official Full Name    sex hormone-binding globulin isoform 1
 NCBI Official Synonym Full Names    sex hormone-binding globulin
 NCBI Official Symbol    SHBG [Similar Products]
 NCBI Official Synonym Symbols   
ABP; SBP; TEBG
[Similar Products]
 NCBI Protein Information    sex hormone-binding globulin
 UniProt Protein Name    Sex hormone-binding globulin
 UniProt Synonym Protein Names   
Sex steroid-binding protein; SBP; Testis-specific androgen-binding protein; ABP; Testosterone-estradiol-binding globulin; TeBG; Testosterone-estrogen-binding globulin
 Protein Family    Sex hormone-binding globulin
 UniProt Gene Name    SHBG [Similar Products]
 UniProt Synonym Gene Names    SHBG; SBP; ABP; TeBG [Similar Products]
 UniProt Entry Name    SHBG_HUMAN
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 NCBI Summary for SHBG    This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
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 UniProt Comments for SHBG    SHBG: Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: extracellular region

Molecular Function: androgen binding
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 Research Articles on SHBG    1. significant association between rs1799941 in SHBG gene and MetS in children
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-SHBG antibodyPathways associated with anti-SHBG antibody
 Reference Product  PubMed Publications
 CYP19A1 antibody  >152 publications with SHBG and CYP19A1
 IGFBP1 antibody  >102 publications with SHBG and IGFBP1
 IGF1 antibody  >21 publications with SHBG and IGF1
 INS antibody  >18 publications with SHBG and INS
 HNF4A antibody  >6 publications with SHBG and HNF4A
 GNRH1 antibody  >2 publications with SHBG and GNRH1
 SERPINA6 antibody  >2 publications with SHBG and SERPINA6
 LEP antibody  >1 publications with SHBG and LEP
 SULT2A1 antibody  >1 publications with SHBG and SULT2A1
 Products by Pathway  Pathway Diagram
 Nongenotropic Androgen Signaling Pathway antibodies  Nongenotropic Androgen Signaling Pathway Diagram
Diseases associated with anti-SHBG antibodyOrgans/Tissues associated with anti-SHBG antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >563 publications with SHBG and Breast Neoplasms
 Cardiovascular Diseases Antibodies  >521 publications with SHBG and Cardiovascular Diseases
 Congenital Abnormalities Antibodies  >372 publications with SHBG and Congenital Abnormalities
 Disorders of Sex Development Antibodies  >358 publications with SHBG and Disorders of Sex Development
 Prostatic Neoplasms Antibodies  >260 publications with SHBG and Prostatic Neoplasms
 Weight Loss Antibodies  >232 publications with SHBG and Weight Loss
 Diabetes Mellitus, Type 2 Antibodies  >226 publications with SHBG and Diabetes Mellitus, Type 2
 Metabolic Syndrome X Antibodies  >187 publications with SHBG and Metabolic Syndrome X
 Hyperplasia Antibodies  >184 publications with SHBG and Hyperplasia
 Infertility, Male Antibodies  >165 publications with SHBG and Infertility, Male
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >558 publications with SHBG and Liver
 Brain Antibodies  >351 publications with SHBG and Brain
 Testis Antibodies  >330 publications with SHBG and Testis
 Eye Antibodies  >15 publications with SHBG and Eye
 Intestine Antibodies  >13 publications with SHBG and Intestine
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