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anti-Sp17 antibody :: Rabbit anti-Human Sperm surface protein Sp17 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS719829 anti-Sp17 antibody
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Sperm surface protein Sp17, Polyclonal Antibody

 Also Known As   

Rabbit anti-human Sperm surface protein Sp17 polyclonal Antibody, FITC

 Product Synonym Names    Cancer/testis antigen 22; Sp17-1; Sperm autoantigenic protein 17
 Product Gene Name   

anti-Sp17 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    608621
 3D Structure    ModBase 3D Structure for Q15506
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    FITC
 Immunogen    Recombinant human Sperm surface protein Sp17 protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-66643 / sc-66640 / sc-135087
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-Sp17 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-Sp17 antibody

   Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates
 Applications Tested/Suitable for anti-Sp17 antibody   

ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for Sp17. It may not necessarily be applicable to this product.
 NCBI GI #    8394343
 NCBI GeneID    53340
 NCBI Accession #    NP_059121.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_017425.3 [Other Products]
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 UniProt Primary Accession #    Q15506 [Other Products]
 UniProt Secondary Accession #    Q9BXF7; B2R4F2 [Other Products]
 UniProt Related Accession #    Q15506 [Other Products]
 Molecular Weight    17,406 Da
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 NCBI Official Full Name    sperm surface protein Sp17
 NCBI Official Synonym Full Names    sperm autoantigenic protein 17
 NCBI Official Symbol    SPA17 [Similar Products]
 NCBI Official Synonym Symbols   
CT22; SP17; SP17-1
[Similar Products]
 NCBI Protein Information    sperm surface protein Sp17
 UniProt Protein Name    Sperm surface protein Sp17
 UniProt Synonym Protein Names   
Cancer/testis antigen 22; CT22; Sp17-1; Sperm autoantigenic protein 17; Sperm protein 17
 Protein Family    Sperm surface protein
 UniProt Gene Name    SPA17 [Similar Products]
 UniProt Synonym Gene Names    SP17; CT22; Sperm protein 17 [Similar Products]
 UniProt Entry Name    SP17_HUMAN
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 NCBI Summary for Sp17    This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.[provided by RefSeq, Jan 2009]
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 UniProt Comments for Sp17    SPA17: Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates.

Protein type: Cancer Testis Antigen (CTA)

Chromosomal Location of Human Ortholog: 11q24.2

Cellular Component: cytoplasm; external side of plasma membrane

Molecular Function: protein binding

Biological Process: binding of sperm to zona pellucida; single fertilization; spermatogenesis
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 Research Articles on Sp17    1. SP17/AKAP4/PTTG1 are expressed in both human NSCLC cell lines and primary tumors and can elicit an immunogenic response in lung cancer patients.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-Sp17 antibodyDiseases associated with anti-Sp17 antibody
 Reference Product  PubMed Publications
 ROPN1 antibody  >2 publications with Sp17 and ROPN1
 ZPBP antibody  >1 publications with Sp17 and ZPBP
 ROPN1L antibody  >1 publications with Sp17 and ROPN1L
 AKAP3 antibody  >1 publications with Sp17 and AKAP3
 Disease Name  Pubmed Publications
 Ovarian Neoplasms Antibodies  >15 publications with Sp17 and Ovarian Neoplasms
 Genital Diseases, Male Antibodies  >5 publications with Sp17 and Genital Diseases, Male
 Liver Neoplasms Antibodies  >4 publications with Sp17 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >3 publications with Sp17 and Carcinoma, Hepatocellular
 Neoplasm Metastasis Antibodies  >2 publications with Sp17 and Neoplasm Metastasis
 Infertility, Female Antibodies  >2 publications with Sp17 and Infertility, Female
 Liver Diseases Antibodies  >2 publications with Sp17 and Liver Diseases
 Testicular Diseases Antibodies  >2 publications with Sp17 and Testicular Diseases
 Infertility, Male Antibodies  >2 publications with Sp17 and Infertility, Male
 Nervous System Diseases Antibodies  >2 publications with Sp17 and Nervous System Diseases
Organs/Tissues associated with anti-Sp17 antibody
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >34 publications with Sp17 and Testis
 Lung Antibodies  >6 publications with Sp17 and Lung
 Liver Antibodies  >5 publications with Sp17 and Liver
 Embryonic Tissue Antibodies  >3 publications with Sp17 and Embryonic Tissue
 Ovary Antibodies  >3 publications with Sp17 and Ovary
 Trachea Antibodies  >2 publications with Sp17 and Trachea
 Prostate Antibodies  >2 publications with Sp17 and Prostate
 Kidney Antibodies  >2 publications with Sp17 and Kidney
 Lymph Node Antibodies  >2 publications with Sp17 and Lymph Node
 Ascites Antibodies  >2 publications with Sp17 and Ascites
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