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anti-SPIN1 antibody :: Rabbit anti-Human Spindlin 1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2032236 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.02 mg  /  $130 +1 FREE 8GB USB
0.05 mg  /  $175 +1 FREE 8GB USB
0.1 mg  /  $225 +1 FREE 8GB USB
0.2 mg  /  $340 +1 FREE 8GB USB
1 mg  /  $800 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Spindlin 1 (SPIN1), Polyclonal Antibody

★Popular Item★
 Also Known As   

Spindlin 1 (SPIN1) Polyclonal Antibody

 Product Gene Name   

anti-SPIN1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    AF106682 mRNA
 3D Structure    ModBase 3D Structure for Q9Y657
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    The antibody is a Rabbit polyclonal antibody raised against SPIN1. It has been selected for its ability to recognize SPIN1 in immunohistochemical staining and western blotting.
 Purity/Purification    Antigen-specific Affinity Chromatography.
 Form/Format    Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol
 Concentration    200ug/ml (lot specific)
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 Source    Polyclonal antibody preparation
 Traits    Liquid
 Immunogen    Recombinant SPIN1 (Met1~Ser262) expressed in E.coli
    
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2068674
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of anti-SPIN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-SPIN1 antibody   

WB; IHC; ICC; IP

 Application Notes for anti-SPIN1 antibody    Western blotting: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml

Optimal working dilutions must be determined by end user
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 Western Blot (WB) of anti-SPIN1 antibody    (Figure. Western Blot; Sample: Recombinant SPIN1, Human.)
anti-SPIN1 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-SPIN1 antibody    (Used in DAB staining on formalin fixed paraffin- embedded Kidney tissue)
anti-SPIN1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for SPIN1. It may not necessarily be applicable to this product.
 NCBI GI #    112293285
 NCBI GeneID    10927
 NCBI Accession #    NP_006708.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_006717.2 [Other Products]
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 UniProt Primary Accession #    Q9Y657 [Other Products]
 UniProt Secondary Accession #    Q7KZJ8; Q9GZT2; Q9H0N7; A8K0X6; B3KRQ4 [Other Products]
 UniProt Related Accession #    Q9Y657 [Other Products]
 Molecular Weight    29,601 Da
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 NCBI Official Full Name    spindlin-1
 NCBI Official Synonym Full Names    spindlin 1
 NCBI Official Symbol    SPIN1 [Similar Products]
 NCBI Official Synonym Symbols   
SPIN; TDRD24
[Similar Products]
 NCBI Protein Information    spindlin-1
 UniProt Protein Name    Spindlin-1
 UniProt Synonym Protein Names   
Ovarian cancer-related protein; Spindlin1
 Protein Family    Spindlin
 UniProt Gene Name    SPIN1 [Similar Products]
 UniProt Synonym Gene Names    OCR; SPIN [Similar Products]
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 UniProt Comments for SPIN1    SPIN1: May play a role in cell-cycle regulation during the transition from gamete to embryo. Belongs to the SPIN/STSY family.

Protein type: DNA-binding; Nucleolus

Chromosomal Location of Human Ortholog: 9q22.1

Cellular Component: cytosol; nuclear membrane; nucleolus; nucleoplasm; nucleus; spindle

Molecular Function: methylated histone residue binding; protein binding

Biological Process: covalent chromatin modification; gamete generation; meiotic cell cycle; multicellular organism development; positive regulation of Wnt receptor signaling pathway; rRNA transcription; Wnt signaling pathway
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 Research Articles on SPIN1    1. These data indicate that miR-489 could reverse the chemoresistance of breast cancer via the PI3K-Akt pathway by targeting SPIN1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Organs/Tissues associated with anti-SPIN1 antibody
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >1 publications with SPIN1 and Muscle
 Testis Antibodies  >1 publications with SPIN1 and Testis
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