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anti-T1R3 antibody :: Rabbit T1R3 / TAS1R3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS244011
Unit / Price
0.05 mg  /  $495 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

T1R3 / TAS1R3, Polyclonal Antibody

 Also Known As   

Rabbit Polyclonal to Human T1R3 / TAS1R3

 Product Synonym Names    Anti-T1R3 / TAS1R3 Antibody (N-Terminus) IHC-plus; TAS1R3; Taste receptor type 1 member 3; TR3; Sweet taste receptor T1R3; T1R3; Human T1R3; TAS1R3
 Product Gene Name   

anti-T1R3 antibody

[Similar Products]
 Product Synonym Gene Name    TAS1R3 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605865
 3D Structure    ModBase 3D Structure for Q7RTX0
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Chimpanzee, Gorilla, Human
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 Specificity    Human TAS1R3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
 Purity/Purification    Immunoaffinity Purified
 Form/Format    PBS, 0.1% sodium azide.
 Concentration    1 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Synthetic 19 amino acid peptide from N-terminal extracellular domain of human TAS1R3. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Baboon (100%); Orangutan (89%).
 Immunogen Type    Synthetic peptide
 Immunogen    T1R3 / TAS1R3 antibody was raised against synthetic 19 amino acid peptide from N-terminal extracellular domain of human TAS1R3. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Baboon (100%); Orangutan (89%).
 Antigen Modification    N-Terminus
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 Preparation and Storage    Long term: -70 degree C; Short term: +4 degree C
 Other Notes    Small volumes of anti-T1R3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-T1R3 antibody

   TAS1R3 is a Taste Receptor. TAS1R3 combines with TAS1R1 to function as an L-amino-acid receptor, and is only activated by these sweet amino acids.
 Product Categories/Family for anti-T1R3 antibody    Family: GPCR
Subfamily: Taste
 Applications Tested/Suitable for anti-T1R3 antibody   

Immunohistochemistry (IHC - Paraffin), Western Blot (WB)

 Application Notes for anti-T1R3 antibody    IHC-P (10 - 20 ug/ml), WB
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 Immunohistochemistry (IHC) of anti-T1R3 antibody    Anti-T1R3 / TAS1R3 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-T1R3 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-T1R3 antibody    Anti-T1R3 / TAS1R3 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-T1R3 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-T1R3 antibody    Anti-TAS1R3 antibody IHC of human tongue, taste receptor. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
anti-T1R3 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for T1R3. It may not necessarily be applicable to this product.
 NCBI GI #    91206396
 NCBI GeneID    83756
 NCBI Accession #    NP_689414.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_152228.1 [Other Products]
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 UniProt Primary Accession #    Q7RTX0 [Other Products]
 UniProt Secondary Accession #    Q5TA49; Q8NGW9 [Other Products]
 UniProt Related Accession #    Q7RTX0 [Other Products]
 Molecular Weight    93,386 Da
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 NCBI Official Full Name    taste receptor type 1 member 3
 NCBI Official Synonym Full Names    taste receptor, type 1, member 3
 NCBI Official Symbol    TAS1R3 [Similar Products]
 NCBI Official Synonym Symbols   
T1R3
[Similar Products]
 NCBI Protein Information    taste receptor type 1 member 3; sweet taste receptor T1R3
 UniProt Protein Name    Taste receptor type 1 member 3
 UniProt Synonym Protein Names   
Sweet taste receptor T1R3
 UniProt Gene Name    TAS1R3 [Similar Products]
 UniProt Synonym Gene Names    T1R3; TR3 [Similar Products]
 UniProt Entry Name    TS1R3_HUMAN
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 NCBI Summary for T1R3    The TAS1R3 gene encodes the human homolog of mouse Sac, a major determinant of differences between sweet-sensitive and -insensitive mouse strains in their responsiveness to sucrose, saccharine, and other sweeteners (Max et al., 2001 [PubMed 11326277]).[supplied by OMIM, Jan 2010]
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 UniProt Comments for T1R3    TAS1R3: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.

Protein type: Receptor, GPCR; GPCR, family 3; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p36.33

Cellular Component: plasma membrane; integral to membrane

Molecular Function: protein heterodimerization activity; sweet taste receptor activity; taste receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; sensory perception of umami taste; sensory perception of sweet taste; detection of chemical stimulus involved in sensory perception of sweet taste
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 Research Articles on T1R3    1. A complex molecular mechanism involving changes in the properties of both the orthosteric and non-orthosteric sites of T1R1 underlies the determination of ligand specificity in mammalian T1R1/T1R3.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to Rabbit Polyclonal to Human T1R3 / TAS1R3
 Catalog #  Product Name  Catalog #  Product Name
 MBS244385  Rabbit Polyclonal to Human T1R3 / TAS1R3  MBS244011  Rabbit Polyclonal to Human T1R3 / TAS1R3
Products associated with anti-T1R3 antibodyPathways associated with anti-T1R3 antibody
 Reference Product  PubMed Publications
 TAS1R2 antibody  >22 publications with T1R3 and TAS1R2
 TAS1R1 antibody  >21 publications with T1R3 and TAS1R1
 GNAT3 antibody  >7 publications with T1R3 and GNAT3
 TAS2R38 antibody  >1 publications with T1R3 and TAS2R38
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 Taste Transduction Pathway antibodies  Taste Transduction Pathway Diagram
Diseases associated with anti-T1R3 antibodyOrgans/Tissues associated with anti-T1R3 antibody
 Disease Name  Pubmed Publications
 Hypoglycemia Antibodies  >1 publications with T1R3 and Hypoglycemia
 Kidney Diseases Antibodies  >1 publications with T1R3 and Kidney Diseases
 Dental Caries Antibodies  >1 publications with T1R3 and Dental Caries
 Carcinoma Antibodies  >1 publications with T1R3 and Carcinoma
 Infertility, Male Antibodies  >1 publications with T1R3 and Infertility, Male
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with T1R3 and Brain
 Liver Antibodies  >3 publications with T1R3 and Liver
 Testis Antibodies  >3 publications with T1R3 and Testis
 Pancreas Antibodies  >2 publications with T1R3 and Pancreas
 Intestine Antibodies  >2 publications with T1R3 and Intestine
 Muscle Antibodies  >2 publications with T1R3 and Muscle
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