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anti-TAAR1 antibody :: Rabbit TAAR1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS221509
Testing Data #1
Unit / Price
0.05 mg  /  $725 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TAAR1, Polyclonal Antibody

 Also Known As   

RABBIT ANTI TAAR1

 Product Gene Name   

anti-TAAR1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    609333
 3D Structure    ModBase 3D Structure for Q96RJ0
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Chimpanzee, Monkey, Orangutan (Expected from Sequence)
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 Form/Format    Purified
Purified IgG - liquid
 Concentration    IgG concentration 1.0mg/ml (lot specific)
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 Perservative Stabilisers    0.1% Sodium Azide (NaN3)
 Histology Positive Control Tissue    Brain, Amygdala
Buffer Solution
 Antiserum Preparation    Antisera to human TAAR1 were raised by repeated immunisations of rabbit with highly purified antigen. Purified IgG prepared by affinity chromatography.
 Target Species    Human
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 Preparation and Storage    Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
 Other Notes    Small volumes of anti-TAAR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-TAAR1 antibody

   Rabbit anti Human TAAR1 antibody recognizes an epitope within Trace amine associated receptor 1 (TAAR1), a G protein-coupled receptor activated by trace amines; endogenous amine compounds present in the mammalian nervous system in trace amounts. TAAR1 may also be activated by metabolites of biogenic amine neurotransmitters including amphetamine-related psychostimulants. TAAR1 is a potentially important target for methamphetamine addiction.
 Applications Tested/Suitable for anti-TAAR1 antibody   

Immunohistology Paraffin

 Application Notes for anti-TAAR1 antibody    Immunohistology - Paraffin: Minimum Dilution: 25; Maximum Dilution: 35ug/ml
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 Testing Data #1 of anti-TAAR1 antibody    Staining of formalin fixed, paraffin embedded human amygdala with Rabbit anti Human TAAR1 (MBS221509)
anti-TAAR1 antibody Testing Data #1 image
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NCBI/Uniprot data below describe general gene information for TAAR1. It may not necessarily be applicable to this product.
 NCBI GI #    21264324
 NCBI GeneID    134864
 NCBI Accession #    NP_612200.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_138327.1 [Other Products]
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 UniProt Primary Accession #    Q96RJ0 [Other Products]
 UniProt Secondary Accession #    Q2M1W5; Q3MIH8; Q5VUQ1 [Other Products]
 UniProt Related Accession #    Q96RJ0 [Other Products]
 Molecular Weight    39,092 Da
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 NCBI Official Full Name    trace amine-associated receptor 1
 NCBI Official Synonym Full Names    trace amine associated receptor 1
 NCBI Official Symbol    TAAR1 [Similar Products]
 NCBI Official Synonym Symbols   
TA1; TAR1; TRAR1
[Similar Products]
 NCBI Protein Information    trace amine-associated receptor 1; taR-1; trace amine receptor 1
 UniProt Protein Name    Trace amine-associated receptor 1
 Protein Family    Trace amine-associated receptor
 UniProt Gene Name    TAAR1 [Similar Products]
 UniProt Synonym Gene Names    TA1; TAR1; TRAR1; TaR-1; Trace amine receptor 1 [Similar Products]
 UniProt Entry Name    TAAR1_HUMAN
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 NCBI Summary for TAAR1    TAAR1 is a G protein-coupled receptor activated by trace amines. Trace amines are endogenous amine compounds that account for less than 1% of the biogenic amines in most brain regions (Bunzow et al., 2001 [PubMed 11723224]).[supplied by OMIM, Mar 2008]
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 UniProt Comments for TAAR1    TAAR1: Receptor for trace amines, including beta- phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonine. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. The signal transduced by this receptor is mediated by the G(s)-class of G-proteins which activate adenylate cyclase. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6q23.2

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; trace-amine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway
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 Research Articles on TAAR1    1. an increase in TAAR1 receptor expression is concomitant with lymphocyte immune activation, suggesting a possible role for TAAR1 in the generation or regulation of an immune response
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-TAAR1 antibodyPathways associated with anti-TAAR1 antibody
 Reference Product  PubMed Publications
 ADRB2 antibody  >3 publications with TAAR1 and ADRB2
 ADRB1 antibody  >1 publications with TAAR1 and ADRB1
 Products by Pathway  Pathway Diagram
 Amine Ligand-binding Receptors Pathway antibodies  Amine Ligand-binding Receptors Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies  Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
Diseases associated with anti-TAAR1 antibodyOrgans/Tissues associated with anti-TAAR1 antibody
 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >6 publications with TAAR1 and Mental Disorders
 Nervous System Diseases Antibodies  >4 publications with TAAR1 and Nervous System Diseases
 Movement Disorders Antibodies  >3 publications with TAAR1 and Movement Disorders
 Attention Deficit Disorder with Hyperactivity Antibodies  >3 publications with TAAR1 and Attention Deficit Disorder with Hyperactivity
 Catalepsy Antibodies  >2 publications with TAAR1 and Catalepsy
 Hypothermia Antibodies  >2 publications with TAAR1 and Hypothermia
 Heart Diseases Antibodies  >1 publications with TAAR1 and Heart Diseases
 Nerve Degeneration Antibodies  >1 publications with TAAR1 and Nerve Degeneration
 Arrhythmias, Cardiac Antibodies  >1 publications with TAAR1 and Arrhythmias, Cardiac
 Headache Antibodies  >1 publications with TAAR1 and Headache
 Organ/Tissue Name  Pubmed Publications
 Stomach Antibodies  >1 publications with TAAR1 and Stomach
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