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anti-TNKS1BP1 antibody :: Goat TAB182 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS420201 anti-TNKS1BP1 antibody
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TAB182 (TNKS1BP1), Polyclonal Antibody

 Also Known As   

Goat anti-TAB182 Antibody

 Product Synonym Names    TNKS1BP1; tankyrase 1 binding protein 1, 182kDa; TAB182; KIAA1741; tankyrase 1-binding protein of 182 kDa; FLJ45975; tankyrase 1-binding protein 1; TNKS1BP1 antibody; tankyrase 1 binding protein 1; 182kDa antibody; TAB182 antibody; KIAA1741 antibody; tankyrase 1-binding protein of 182 kDa antibody; FLJ45975 antibody; tankyrase 1-binding protein 1 antibody
 Product Gene Name   

anti-TNKS1BP1 antibody

[Similar Products]
 Product Synonym Gene Name    TAB182 [Similar Products]
 Antibody/Peptide Pairs    TAB182 peptide (MBS425347) is used for blocking the activity of TAB182 antibody (MBS420201)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    KVSTLRESSA MAS
 OMIM    607104
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Expected from sequence similarity: Human
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence KVSTLRESSAMAS-C, from the N Terminus of the protein sequence according to NP_203754.2.
 Epitope    N Terminus
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-TNKS1BP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-TNKS1BP1 antibody   

Peptide ELISA (EIA)

 Application Notes for anti-TNKS1BP1 antibody    Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Preliminary experiments in Human Ovary and Lung lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).
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NCBI/Uniprot data below describe general gene information for TNKS1BP1. It may not necessarily be applicable to this product.
 NCBI GI #    110556636
 NCBI GeneID    85456
 NCBI Accession #    NP_203754.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_033396.2 [Other Products]
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 UniProt Secondary Accession #    Q6PJ35; Q6ZV74; A7E2F8 [Other Products]
 UniProt Related Accession #    Q9C0C2 [Other Products]
 Molecular Weight    82,677 Da
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 NCBI Official Full Name    182 kDa tankyrase-1-binding protein
 NCBI Official Synonym Full Names    tankyrase 1 binding protein 1
 NCBI Official Symbol    TNKS1BP1 [Similar Products]
 NCBI Official Synonym Symbols   
TAB182
[Similar Products]
 NCBI Protein Information    182 kDa tankyrase-1-binding protein
 UniProt Protein Name    182 kDa tankyrase-1-binding protein
 Protein Family    182 kDa tankyrase-1-binding protein
 UniProt Gene Name    TNKS1BP1 [Similar Products]
 UniProt Synonym Gene Names    KIAA1741; TAB182 [Similar Products]
 UniProt Entry Name    TB182_HUMAN
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 UniProt Comments for TNKS1BP1    TNKS1BP1: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Actin-binding; Cell cycle regulation

Chromosomal Location of Human Ortholog: 11q12.1

Cellular Component: CCR4-NOT complex; cytoplasm; cytoskeleton; cytosol; nuclear telomeric heterochromatin; nucleoplasm; nucleus; plasma membrane

Molecular Function: ankyrin binding; enzyme binding

Biological Process: DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; poly(A) tail shortening; telomere maintenance via telomerase
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 Research Articles on TNKS1BP1    1. TNKS1BP1 has a role in DNA double-strand break repair though DNA-PKcs autophosphorylation which is dependent on PARP-1
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-TNKS1BP1 antibodyPathways associated with anti-TNKS1BP1 antibody
 Reference Product  PubMed Publications
 TNKS antibody  >3 publications with TNKS1BP1 and TNKS
 Products by Pathway  Pathway Diagram
 Deadenylation Of MRNA Pathway antibodies  Deadenylation Of MRNA Pathway Diagram
 Deadenylation-dependent MRNA Decay Pathway antibodies  Deadenylation-dependent MRNA Decay Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 TP53 Regulates Transcription Of Cell Cycle Genes Pathway antibodies  TP53 Regulates Transcription Of Cell Cycle Genes Pathway Diagram
 TP53 Regulates Transcription Of Additional Cell Cycle Genes Whose Exact Role In The P53 Pathway Remain Uncertain antibodies  TP53 Regulates Transcription Of Additional Cell Cycle Genes Whose Exact Role In The P53 Pathway Remain Uncertain Diagram
 Transcriptional Regulation By TP53 Pathway antibodies  Transcriptional Regulation By TP53 Pathway Diagram
Diseases associated with anti-TNKS1BP1 antibodyOrgans/Tissues associated with anti-TNKS1BP1 antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >1 publications with TNKS1BP1 and Breast Neoplasms
 Carcinoma Antibodies  >1 publications with TNKS1BP1 and Carcinoma
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >1 publications with TNKS1BP1 and Muscle
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