Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow TAC1 rightarrow Polyclonal TAC1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • defensin, alpha 7 (DEFA7) ELISA Kit
 • Beta-galactosidase (Glb1) Recombinant Protein
 • Interleukin-12p40 (IL-12p40) Antibody
 • D-Dimer (D2D) ELISA Kit
 • Toxin CfTX-1 (Toxin 1) Recombinant Protein
 • MEMO1 Antibody
 • Soluble Vascular Endothelial Growth Factor Receptor 2 (VEGFR... ELISA Kit
 • Rab25 Antibody
 • Marek's disease virus IgG (MDV-Ab-IgG) ELISA Kit
 • Histidine NADH Dehydrogenase Fe-S Protein 4 (NDUFS4) Recombinant Protein
 • Caspase 3 (CASP3) ELISA Kit
 • basic helix-loop-helix family, member e41 (BHLHE41) ELISA Kit
 • Murinoglobulin-1 (MUG1) Recombinant Protein
 • 2',5'-Oligoadenylate Synthetase 2 (OAS2) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-TAC1 antibody :: Rabbit anti-Human TAC1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS6009007 anti-TAC1 antibody
Unit / Price
0.2 mL  /  $550 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TAC1, Polyclonal Antibody

 Also Known As   

TAC1, CT (TAC1, NKA, NKNA, TAC2, Protachykinin-1, PPT, Substance P, Neurokinin A, Neuromedin L, Substance K, Neuropeptide K, Neuropeptide gamma, C-terminal-flanking peptide)

 Product Synonym Names    Anti -TAC1, CT (TAC1, NKA, NKNA, TAC2, Protachykinin-1, PPT, Substance P, Neurokinin A, Neuromedin L, Substance K, Neuropeptide K, Neuropeptide gamma, C-terminal-flanking peptide)
 Product Gene Name   

anti-TAC1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Chromosome Location    Chromosome: 7; NC_000007.13 (97361271..97369784). Location: 7q21-q22
 OMIM    162320
 3D Structure    ModBase 3D Structure for P20366
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
Section Bar
 Specificity    Human
 Purity/Purification    Affinity Purified
Purified by Protein A affinity chromatography.
 Form/Format    Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Section Bar
 Immunogen    TAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-137 amino acids from the C-terminal region of human TAC1.
Section Bar
 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
 Other Notes    Small volumes of anti-TAC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Product Categories/Family for anti-TAC1 antibody    Antibodies; Abs to Neuroscience
 Applications Tested/Suitable for anti-TAC1 antibody   

ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)

 Application Notes for anti-TAC1 antibody    Suitable for use in Western Blot, Flow Cytometry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Flow Cytometry: 1:10-50
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for TAC1. It may not necessarily be applicable to this product.
 NCBI GI #    49456421
 NCBI GeneID    6863
 NCBI Accession #    CAG46531.1 [Other Products]
Section Bar
 UniProt Primary Accession #    P20366 [Other Products]
 UniProt Secondary Accession #    O60600; O60601; Q00072; Q53GH4; Q549V0; Q549V1; Q549V2; Q6FHM1 [Other Products]
 UniProt Related Accession #    P20366 [Other Products]
 Molecular Weight    15,003 Da [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    TAC1
 NCBI Official Synonym Full Names    tachykinin, precursor 1
 NCBI Official Symbol    TAC1 [Similar Products]
 NCBI Official Synonym Symbols   
NK2; NPK; NKNA; TAC2; Hs.2563
[Similar Products]
 NCBI Protein Information    protachykinin-1; PPT; substance K; substance P; neurokinin 1; neurokinin 2; neurokinin A; neuromedin L; tachykinin 2; neuropeptide K; neurokinin alpha; preprotachykinin; neuropeptide gamma; tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)
 UniProt Protein Name    Protachykinin-1
 UniProt Synonym Protein Names   
PPTCleaved into the following 5 chains:Substance PNeurokinin A; NKA; Alternative name(s):; Neuromedin L; Substance K
 Protein Family    Transcriptional regulator
 UniProt Gene Name    TAC1 [Similar Products]
 UniProt Synonym Gene Names    NKA; NKNA; TAC2; NKA; NPK [Similar Products]
 UniProt Entry Name    TKN1_HUMAN
Section Bar
 NCBI Summary for TAC1    This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for TAC1    TAC1: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Belongs to the tachykinin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7q21-q22

Cellular Component: extracellular space; cell soma; axon; extracellular region; plasma membrane

Molecular Function: protein binding; substance P receptor binding

Biological Process: tachykinin signaling pathway; negative regulation of heart rate; insemination; response to hormone stimulus; response to morphine; response to lipopolysaccharide; response to pain; sensory perception of pain; positive regulation of saliva secretion; synaptic transmission; elevation of cytosolic calcium ion concentration; cell-cell signaling; positive regulation of lymphocyte proliferation; positive regulation of acute inflammatory response; neuropeptide signaling pathway; regulation of blood pressure; positive regulation of stress fiber formation; positive regulation of action potential; inflammatory response; associative learning; detection of abiotic stimulus; positive regulation of synaptic transmission, cholinergic; positive regulation of synaptic transmission, GABAergic; positive regulation of ossification; long-term memory
Table BarTOPTable Bar
 Research Articles on TAC1    1. Our results suggest that Substance P plays an important role in the development of pancreatic cancer metastasis and PNI, and blocking the SP/NK-1R signaling system is a novel strategy for the treatment of pancreatic cancer.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-TAC1 antibodyPathways associated with anti-TAC1 antibody
 Reference Product  PubMed Publications
 TACR1 antibody  >23 publications with TAC1 and TACR1
 TAC3 antibody  >8 publications with TAC1 and TAC3
 TACR2 antibody  >6 publications with TAC1 and TACR2
 TACR3 antibody  >5 publications with TAC1 and TACR3
 NTS antibody  >3 publications with TAC1 and NTS
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 SIDS Susceptibility Pathways antibodies  SIDS Susceptibility Pathways Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 Tachykinin Receptors Bind Tachykinins Pathway antibodies  Tachykinin Receptors Bind Tachykinins Pathway Diagram
Diseases associated with anti-TAC1 antibodyOrgans/Tissues associated with anti-TAC1 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >17 publications with TAC1 and Inflammation
 Nervous System Diseases Antibodies  >16 publications with TAC1 and Nervous System Diseases
 Pain Antibodies  >13 publications with TAC1 and Pain
 Disease Models, Animal Antibodies  >10 publications with TAC1 and Disease Models, Animal
 Hyperalgesia Antibodies  >7 publications with TAC1 and Hyperalgesia
 Neurogenic Inflammation Antibodies  >5 publications with TAC1 and Neurogenic Inflammation
 Bipolar Disorder Antibodies  >5 publications with TAC1 and Bipolar Disorder
 Schizophrenia Antibodies  >4 publications with TAC1 and Schizophrenia
 Necrosis Antibodies  >3 publications with TAC1 and Necrosis
 Edema Antibodies  >2 publications with TAC1 and Edema
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >31 publications with TAC1 and Brain
 Nerve Antibodies  >15 publications with TAC1 and Nerve
 Embryonic Tissue Antibodies  >2 publications with TAC1 and Embryonic Tissue
 Eye Antibodies  >2 publications with TAC1 and Eye
 Uncharacterized Tissue Antibodies  >1 publications with TAC1 and Uncharacterized Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions