NP_001128690.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 21 kDa Predicted: 18 kDa
NCBI Official Full Name
transcription initiation factor TFIID subunit 12
NCBI Official Synonym Full Names
TATA-box binding protein associated factor 12
NCBI Protein Information
transcription initiation factor TFIID subunit 12
UniProt Protein Name
Transcription initiation factor TFIID subunit 12
UniProt Synonym Protein Names
Transcription initiation factor TFIID 20/15 kDa subunits; TAFII-20/TAFII-15; TAFII20/TAFII15
UniProt Synonym Gene Names
NCBI Summary for TAF12
Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2008]
UniProt Comments for TAF12
TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of RNA polymerase transcription.
Research Articles on TAF12
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Products associated with anti-TAF12 antibody
Pathways associated with anti-TAF12 antibody
Diseases associated with anti-TAF12 antibody
Organs/Tissues associated with anti-TAF12 antibody
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