NP_114129.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
transcription initiation factor TFIID subunit 3
NCBI Official Synonym Full Names
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
NCBI Protein Information
transcription initiation factor TFIID subunit 3
UniProt Protein Name
Transcription initiation factor TFIID subunit 3
UniProt Synonym Protein Names
140 kDa TATA box-binding protein-associated factor; TBP-associated factor 3; Transcription initiation factor TFIID 140 kDa subunit; TAF(II)140; TAF140; TAFII-140; TAFII140
UniProt Synonym Gene Names
UniProt Entry Name
TAF3_HUMAN
NCBI Summary for TAF3
The highly conserved RNA polymerase II transcription factor TFIID (see TAF1; MIM 313650) comprises the TATA box-binding protein (TBP; MIM 600075) and a set of TBP-associated factors (TAFs), including TAF3. TAFs contribute to promoter recognition and selectivity and act as antiapoptotic factors (Gangloff et al., 2001 [PubMed 11438666]).[supplied by OMIM, May 2009]
UniProt Comments for TAF3
TAF140: Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process. Belongs to the TAF3 family.
Protein type: Transcription initiation complex
Chromosomal Location of Human Ortholog: 10p15.1
Cellular Component: nucleoplasm; transcription factor TFIID complex; nucleus
Molecular Function: protein binding; zinc ion binding; p53 binding
Biological Process: transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; viral reproduction; negative regulation of transcription factor activity; RNA elongation from RNA polymerase II promoter; gene expression; negative regulation of transcription from RNA polymerase II promoter; maintenance of protein localization in nucleus
Product References and Citations for anti-TAF3 antibody
Trynka, G., et al. Gut 58(8):1078-1083(2009) Luke, M.M., et al. Stroke 40(2):363-368(2009) Shiffman, D., et al. Arterioscler. Thromb. Vasc. Biol. 28(1):173-179(2008)
Research Articles on TAF3
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-TAF3 antibody
Pathways associated with anti-TAF3 antibody
Products by Pathway |
Pathway Diagram |
, Pathway antibodies |
, Pathway Diagram |
, Pathway antibodies |
, Pathway Diagram |
, Pathway antibodies |
, Pathway Diagram |
, Pathway antibodies |
, Pathway Diagram |
, Pathway antibodies |
, Pathway Diagram |
, Pathway antibodies |
, Pathway Diagram |
, Pathway antibodies |
, Pathway Diagram |
, Pathway antibodies |
, Pathway Diagram |
, Pathway antibodies |
, Pathway Diagram |
, Pathway antibodies |
, Pathway Diagram |
Diseases associated with anti-TAF3 antibody
Organs/Tissues associated with anti-TAF3 antibody
|