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anti-TAF5 antibody :: Rabbit anti-Human TAF5 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7045320
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TAF5, Polyclonal Antibody

★Popular Item★
 Also Known As   

TAF5 Antibody

 Product Synonym Names    Transcription initiation factor TFIID subunit 5; Transcription initiation factor TFIID 100 kDa subunit; TAF(II)100; TAFII-100; TAFII100; TAF5; TAF2D
 Product Gene Name   

anti-TAF5 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    601787
 3D Structure    ModBase 3D Structure for Q15542
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human Transcription initiation factor TFIID subunit 5 protein (C-145AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-109058 / sc-98823
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-TAF5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-TAF5 antibody

   TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of RNA polymerase transcription. TAF5/TAFII100 interacts strongly with the histone H4-related TAF6/TAFII80 and the histone H3-related TAF9/TAFII31, as well as a stable complex comprised of both TAF5/TAFII80 and TAF6/TAFII31. Apparently weaker interactions of TAF5/TAFII100 with TBP, TAF1/TAFII250, TAF11/TAFII28, and TAF12/TAFII20, but not TAF7/TAFII55, also have been observed.
 Applications Tested/Suitable for anti-TAF5 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-TAF5 antibody    Western blot
All lanes: TAF5 antibody at 1.74 ug/ml
Lane 1: Jurkat whole cell lysate
Lane 2: MCF7 whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 87,81 kDa
Observed band size: 87 kDa,40 kDa,51 kDa

anti-TAF5 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-TAF5 antibody    Immunohistochemistry of paraffin-embedded human liver cancer using MBS7045320 at dilution 1:100
anti-TAF5 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for TAF5. It may not necessarily be applicable to this product.
 NCBI GI #    21071067
 NCBI GeneID    6877
 NCBI Accession #    NP_008882.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_006951.4 [Other Products]
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 UniProt Primary Accession #    Q15542 [Other Products]
 UniProt Secondary Accession #    Q53EM4; Q5SYD5; Q86UZ7; Q9Y4K5; A8K5B4; B2RMR0; B7ZKJ6 [Other Products]
 UniProt Related Accession #    Q15542 [Other Products]
 Molecular Weight    80,508 Da
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 NCBI Official Full Name    transcription initiation factor TFIID subunit 5 isoform 1
 NCBI Official Synonym Full Names    TATA-box binding protein associated factor 5
 NCBI Official Symbol    TAF5 [Similar Products]
 NCBI Official Synonym Symbols   
TAF2D; TAFII100; TAFII-100; TAF(II)100
[Similar Products]
 NCBI Protein Information    transcription initiation factor TFIID subunit 5
 UniProt Protein Name    Transcription initiation factor TFIID subunit 5
 UniProt Synonym Protein Names   
Transcription initiation factor TFIID 100 kDa subunit; TAF(II)100; TAFII-100; TAFII100
 Protein Family    Transcription initiation factor
 UniProt Gene Name    TAF5 [Similar Products]
 UniProt Synonym Gene Names    TAF2D; TAF(II)100; TAFII-100; TAFII100 [Similar Products]
 UniProt Entry Name    TAF5_HUMAN
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 NCBI Summary for TAF5    Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes an integral subunit of TFIID associated with all transcriptionally competent forms of that complex. This subunit interacts strongly with two TFIID subunits that show similarity to histones H3 and H4, and it may participate in forming a nucleosome-like core in the TFIID complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
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 UniProt Comments for TAF5    TAF5: TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of RNA polymerase transcription. TAF5/TAFII100 interacts strongly with the histone H4-related TAF6/TAFII80 and the histone H3-related TAF9/TAFII31, as well as a stable complex comprised of both TAF5/TAFII80 and TAF6/TAFII31. Apparently weaker interactions of TAF5/TAFII100 with TBP, TAF1/TAFII250, TAF11/TAFII28, and TAF12/TAFII20, but not TAF7/TAFII55, also have been observed. Belongs to the WD repeat TAF5 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 10q24-q25.2

Cellular Component: actin cytoskeleton; intracellular membrane-bound organelle; nucleolus; nucleoplasm; nucleus; transcription factor TFIID complex

Molecular Function: histone acetyltransferase activity; protein binding; protein dimerization activity; transcription factor activity

Biological Process: chromatin modification; RNA elongation from RNA polymerase II promoter; snRNA transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation; transcription initiation from RNA polymerase II promoter
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 Research Articles on TAF5    1. results show that nonproductive binding of OGG1 to 8-oxoG in promoter sequences could be an epigenetic mechanism to modulate gene expression for a prompt innate immune response.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-TAF5 antibodyDiseases associated with anti-TAF5 antibody
 Products by Pathway  Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Eukaryotic Transcription Initiation Pathway antibodies  Eukaryotic Transcription Initiation Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 HIV Infection Pathway antibodies  HIV Infection Pathway Diagram
 HIV Life Cycle Pathway antibodies  HIV Life Cycle Pathway Diagram
 HIV Transcription Initiation Pathway antibodies  HIV Transcription Initiation Pathway Diagram
 Herpes Simplex Infection Pathway antibodies  Herpes Simplex Infection Pathway Diagram
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >1 publications with TAF5 and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >1 publications with TAF5 and Neoplasm Metastasis
 Infertility, Female Antibodies  >1 publications with TAF5 and Infertility, Female
 Adenocarcinoma Antibodies  >1 publications with TAF5 and Adenocarcinoma
 Cell Transformation, Neoplastic Antibodies  >1 publications with TAF5 and Cell Transformation, Neoplastic
 Inflammation Antibodies  >1 publications with TAF5 and Inflammation
Organs/Tissues associated with anti-TAF5 antibody
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >3 publications with TAF5 and Embryonic Tissue
 Lymph Node Antibodies  >1 publications with TAF5 and Lymph Node
 Testis Antibodies  >1 publications with TAF5 and Testis
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