NP_689414.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
taste receptor type 1 member 3
NCBI Official Synonym Full Names
taste receptor, type 1, member 3
NCBI Official Synonym Symbols
NCBI Protein Information
taste receptor type 1 member 3
UniProt Protein Name
Taste receptor type 1 member 3
UniProt Synonym Protein Names
Sweet taste receptor T1R3
UniProt Synonym Gene Names
UniProt Entry Name
TS1R3_HUMAN
NCBI Summary for TAS1R3
The TAS1R3 gene encodes the human homolog of mouse Sac, a major determinant of differences between sweet-sensitive and -insensitive mouse strains in their responsiveness to sucrose, saccharine, and other sweeteners (Max et al., 2001 [PubMed 11326277]).[supplied by OMIM, Jan 2010]
UniProt Comments for TAS1R3
TAS1R3: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.
Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 3; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 1p36.33
Cellular Component: integral to membrane; plasma membrane
Molecular Function: protein heterodimerization activity; sweet taste receptor activity; taste receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; sensory perception of umami taste; sensory perception of sweet taste; detection of chemical stimulus involved in sensory perception of sweet taste
Product References and Citations for anti-TAS1R3 antibody
Assadi-Porter, F.M., et al. J. Mol. Biol. 398(4):584-599(2010) Assadi-Porter, F.M., et al. Biochim. Biophys. Acta 1798(2):82-86(2010) Chen, Q.Y., et al. Am. J. Clin. Nutr. 90 (3), 770S-779S (2009) : Chandrashekar, J., et al. Nature 444(7117):288-294(2006) Xu, H., et al. Proc. Natl. Acad. Sci. U.S.A. 101(39):14258-14263(2004)
Research Articles on TAS1R3
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Products associated with anti-TAS1R3 antibody
Pathways associated with anti-TAS1R3 antibody
Diseases associated with anti-TAS1R3 antibody
Organs/Tissues associated with anti-TAS1R3 antibody
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